{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T15:07:49Z","timestamp":1770908869499,"version":"3.50.1"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"12","funder":[{"name":"National Institute of Child Health and Human Development","award":["K23 HD097254"],"award-info":[{"award-number":["K23 HD097254"]}]},{"name":"National Institute of Health Research Training Program","award":["NIH 5T32HL007849-22"],"award-info":[{"award-number":["NIH 5T32HL007849-22"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:p>\n            Objective\u2003Gastroschisis is the most common congenital abdominal wall defect, with an increasing incidence. It results in extrusion of abdominal contents with associated delayed intestinal motility. Abnormal heart rate characteristics (HRCs) such as decreased variability occur due to the inflammatory response to sepsis in preterm infants. This study aimed to test the hypothesis that infants with gastroschisis have decreased heart rate variability (HRV) after birth and that this physiomarker may predict outcomes.<\/jats:p><jats:p>\n            Study Design\u2003We analyzed heart rate data from and clinical variables for all infants admitted with gastroschisis from 2009 to 2020.<\/jats:p><jats:p>\n            Results\u2003Forty-seven infants were admitted during the study period and had available data. Complex gastroschisis infants had reduced HRV after birth. For those with sepsis and necrotizing enterocolitis, abnormal HRCs occurred early in the course of illness.<\/jats:p><jats:p>\n            Conclusion\u2003Decreased HRV was associated with complex gastroschisis. Infants in this group experienced complications that prolonged time to full enteral feeding and time on total parenteral nutrition.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2244-0148","type":"journal-article","created":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T00:44:47Z","timestamp":1705106687000},"page":"1660-1664","source":"Crossref","is-referenced-by-count":3,"title":["Heart Rate Variability as a Prognostic Tool for Gastroschisis Infants in the Neonatal Intensive Critical Unit"],"prefix":"10.1055","volume":"41","author":[{"given":"Chioma","family":"Moneme","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Virginia, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherry L.","family":"Kausch","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The University of Virginia, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Briana M.","family":"Belmonte","sequence":"additional","affiliation":[{"name":"School of Medicine, The University of Virginia, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8589-2439","authenticated-orcid":false,"given":"Mark A.","family":"Fleming II","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Virginia, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel E.","family":"Levin","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Virginia, Charlottesville, Virginia"},{"name":"Department of Pediatric Surgery, The University of Virginia, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9580-4121","authenticated-orcid":false,"given":"Brynne A.","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The University of Virginia, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.15585\/mmwr.mm6802a2","article-title":"Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates - United States, 2006\u20132015","volume":"68","author":"T D Short","year":"2019","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"23","DOI":"10.15585\/mmwr.mm6502a2","article-title":"Increasing prevalence of gastroschisis\u201314 states, 1995\u20132012","volume":"65","author":"A MIJ Jones","year":"2016","journal-title":"MMWR Morb Mortal Wkly 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gastroschisis","volume":"260","author":"S R Komic","year":"2021","journal-title":"J Surg Res"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1007\/s00431-021-03964-w","article-title":"The association of perinatal and clinical factors with outcomes in infants with gastroschisis-a retrospective multicenter study in Finland","volume":"180","author":"A Tauriainen","year":"2021","journal-title":"Eur J Pediatr"},{"issue":"10","key":"ref8","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.jpedsurg.2014.08.001","article-title":"Complex gastroschisis is a different entity to simple gastroschisis affecting morbidity and mortality-a systematic review and meta-analysis","volume":"49","author":"R Bergholz","year":"2014","journal-title":"J Pediatr Surg"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1055\/s-0029-1241729","article-title":"Outcomes in neonates with gastroschisis in U.S. children's 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