{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:42:57Z","timestamp":1788536577648,"version":"build-2803163510"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"name":"Chase Koch Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n            Objective\u2003The objective of this study is to assess whether, among a cohort of placenta accreta spectrum (PAS) patients, antenatal suspicion of PAS was less likely in in vitro fertilization (IVF) compared with non-IVF patients. In addition, we aimed to assess whether IVF patients exhibited similar risk factors for PAS compared with non-IVF patients.<\/jats:p><jats:p>\n            Study Design\u2003This is an international multicenter retrospective study of patients with pathologically confirmed PAS (accreta, increta, percreta) between 1998 and 2021. PAS patients were identified through a central international PAS database. Antenatal and pathological criteria are specific to each institution. Pregnancies that resulted from IVF were compared with non-IVF pregnancies. Comparisons were made using a chi-square or Fisher's exact test for categorical variables and Wilcoxon rank-sum test for continuous variables.<\/jats:p><jats:p>\n            Results\u2003Of the 692 pregnancies included, 44 were in the IVF group and 648 were in the non-IVF group. The IVF group was less likely to have had a prior cesarean delivery (70.5 vs. 91%, p\u2009&lt;\u20090.01) but a similar prevalence of placenta previa (63.6 vs. 68.1%, p\u2009=\u20090.12) compared with the non-IVF group. The IVF group was also less likely to have either a prior cesarean delivery or placenta previa than the non-IVF group (79.5 vs. 95.4%, p\u2009&lt;\u20090.01). Antenatal detection of PAS was less common in the IVF group compared with the non-IVF group (40.9 vs. 60.5%, p\u2009&lt;\u20090.01, respectively), even when adjusted for maternal age, prior cesarean delivery, prior uterine surgery, placenta previa and site (risk ratio: 0.70, 95% confidence interval: 0.62\u20130.81). The IVF group had less severe pathological disease compared with the non-IVF group (p\u2009=\u20090.02).<\/jats:p><jats:p>\n            Conclusion\u2003Pregnant people with PAS who underwent IVF are less likely to have an antenatal suspicion compared with non-IVF patients. This finding may be explained by the lower incidence of prior cesarean deliveries and\/or placenta previa as well as less severe forms of PAS.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2257-3864","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:04:51Z","timestamp":1706659491000},"page":"120-125","source":"Crossref","is-referenced-by-count":4,"title":["Risk Profiling In Vitro Fertilization Pregnancies that Develop Placenta Accreta Spectrum"],"prefix":"10.1055","volume":"42","author":[{"given":"Anna M.","family":"Modest","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett D.","family":"Einerson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albaro J.","family":"Nieto","sequence":"additional","affiliation":[{"name":"Departamento de Ginecolog\u00eda y Obstetricia, Unidad de Alta Complejidad Obst\u00e9trica, Fundaci\u00f3n Cl\u00ednica Valle del Lili, Cali, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineet K.","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Miller Children's & Women's Hospital\/Long Beach, Long Beach, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza A.","family":"Shamshirsaz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas"},{"name":"Maternal Fetal Care Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6062-6772","authenticated-orcid":false,"given":"Scott A.","family":"Shainker","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Pan American Society for Placenta Accreta Spectrum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"384.e1","DOI":"10.1016\/j.ajog.2015.05.002","article-title":"Morbidity associated with cesarean delivery in the United States: is placenta accreta an increasingly important contributor?","volume":"213","author":"A A Creanga","year":"2015","journal-title":"Am J 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