{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T05:30:12Z","timestamp":1730871012399,"version":"3.28.0"},"reference-count":43,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Ziel dieser Arbeit war es, die Technik einer laparoskopischen Gastrektomie bei Magenkarzinom darzustellen sowie in einem Review die aktuelle internationale Studienlage zu diesem Thema zusammenzufassen.<\/jats:p><jats:p>Im 1. Teil wird eine laparoskopische Standardgastrektomie bei Karzinom beschrieben und dokumentiert. Im 2. Teil werden nach einer EMBASE- und PubMed-Suche aus prim\u00e4r 3042 Treffern durch systematisches Eingrenzen insgesamt 123 qualit\u00e4tsrelevante randomisierte (RCT) und nicht randomisierte (non-RCT) Studien zur laparoskopischen Gastrektomie identifiziert. Danach werden die Studienergebnisse konklusiv f\u00fcr die Zielkriterien Durchf\u00fchrbarkeit, Outcome, onkologische Qualit\u00e4t sowie Morbidit\u00e4t und Mortalit\u00e4t zusammengefasst.<\/jats:p><jats:p>Sowohl die laparoskopisch subtotale Resektion bei distalen Magenkarzinomen wie auch die laparoskopische Gastrektomie sind inzwischen sicher und komplikationsarm durchf\u00fchrbar. In einem aktuellen Literaturreview \u00fcber insgesamt 15 RCT mit 5576 Patienten (laparoskopisch 2793 vs. offen 2756) ergaben sich keine signifikanten Unterschiede in Bezug auf Durchf\u00fchrbarkeit, intraoperatives Outcome und onkologische Qualit\u00e4t (R0-Status und Lymphknotenausbeute). Die chirurgische Morbidit\u00e4t und Mortalit\u00e4t waren vergleichbar. Patienten nach laparoskopischer Operation zeigten eine signifikant schnellere fr\u00fchpostoperative Erholung mit einer geringeren Gesamtmorbidit\u00e4t. Im Gegensatz dazu war die Operationszeit im Vergleich zur offenen Technik um durchschnittlich 45\u00a0min signifikant verl\u00e4ngert. Die Vorteile der laparoskopischen Technik bildeten sich in Studien zum Magenfr\u00fchkarzinom und bei fortgeschrittenen Karzinomen (&gt;T2) gleicherma\u00dfen ab.<\/jats:p><jats:p>Die laparoskopische Gastrektomie bei Magenkarzinom ist sicher durchf\u00fchrbar und zeigt eine bessere fr\u00fchpostoperative Erholung. Komplikationsraten, Morbidit\u00e4t und Mortalit\u00e4t sowie onkologische Langzeitergebnisse sind mit der offenen Chirurgie vergleichbar.<\/jats:p>","DOI":"10.1055\/a-2258-0298","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:32:44Z","timestamp":1709166764000},"page":"169-177","source":"Crossref","is-referenced-by-count":1,"title":["Technik und Studienlage der laparoskopischen Gastrektomie bei Magenkarzinom"],"prefix":"10.1055","volume":"149","author":[{"given":"Kaja","family":"Ludwig","sequence":"additional","affiliation":[{"name":"Chirurgie, Klinikum S\u00fcdstadt Rostock, Klinik f\u00fcr Allgemein-, Viszeral-, Thorax- und Gef\u00e4\u00dfchirurgie, Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Scharlau","sequence":"additional","affiliation":[{"name":"Chirurgie, Klinikum S\u00fcdstadt Rostock, Klinik f\u00fcr Allgemein-, Viszeral-, Thorax- und Gef\u00e4\u00dfchirurgie, Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylke","family":"Schneider-Koriath","sequence":"additional","affiliation":[{"name":"Chirurgie, Klinikum S\u00fcdstadt Rostock, Klinik f\u00fcr Allgemein-, Viszeral-, Thorax- und Gef\u00e4\u00dfchirurgie, Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"F Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1055\/a-1018-2516","article-title":"S3-Leitlinie Magenkarzinom \u2013 Diagnostik und Therapie der Adenokarzinome des Magens und \u00f6sophagogastralen \u00dcbergangs. Langversion 2.0 \u2013 August 2019. AWMF-Registernummer: 032\/009OL","volume":"57","author":"M Moehler","year":"2019","journal-title":"Z Gastroenterol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"CD011389","DOI":"10.1002\/14651858.CD011389.pub2","article-title":"Laparoscopic versus open gastrectomy for gastric cancer","volume":"3","author":"LMJ Best","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"S306","DOI":"10.1067\/msy.2002.120115","article-title":"A randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: an interim report","volume":"131(1 Suppl)","author":"S Kitano","year":"2002","journal-title":"Surgery"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1007\/s00464-004-8207-4","article-title":"Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer","volume":"19","author":"H Hayashi","year":"2005","journal-title":"Surg Endosc"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1007\/s00464-004-8808-y","article-title":"A prospective randomized study comparing open vs laparoscopy-assisted distal gastrectomy in early gastric cancer: early results","volume":"19","author":"JH Lee","year":"2005","journal-title":"Surg Endosc"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1007\/s00464-012-2658-9","article-title":"Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial","volume":"27","author":"S Sakuramoto","year":"2013","journal-title":"Surg Endosc"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1007\/s00268-013-2121-7","article-title":"Laparoscopy-assisted distal gastrectomy versus open distal gastrectomy. A prospective randomized single-blind study","volume":"37","author":"S Takiguchi","year":"2013","journal-title":"World J Surg"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1007\/s00595-015-1221-4","article-title":"Laparoscopic versus open distal gastrectomy for early gastric cancer in Japan: long-term clinical outcomes of a randomized clinical trial","volume":"46","author":"K Yamashita","year":"2016","journal-title":"Surg Today"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1097\/SLA.0000000000001346","article-title":"Decreased morbidity of laparoscopic distal gastrectomy compared with open distal gastrectomy for stage I gastric cancer: short-term outcomes from a multicenter randomized controlled trial (KLASS-01)","volume":"263","author":"W Kim","year":"2016","journal-title":"Ann Surg"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/s10120-016-0646-9","article-title":"Short-term surgical outcomes from a phase III study of laparoscopy-assisted versus open distal gastrectomy with nodal dissection for clinical stage IA\/IB gastric cancer: Japan Clinical Oncology Group Study JCOG0912","volume":"20","author":"H Katai","year":"2017","journal-title":"Gastric Cancer"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1097\/01.sla.0000151892.35922.f2","article-title":"Laparoscopic versus open subtotal gastrectomy for distal gastric cancer: five-year results of a randomized prospective trial","volume":"241","author":"CGS Huscher","year":"2005","journal-title":"Ann Surg"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.1200\/JCO.2015.63.7215","article-title":"Morbidity and Mortality of Laparoscopic Versus Open D2 Distal Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial","volume":"34","author":"Y Hu","year":"2016","journal-title":"J Clin Oncol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1097\/SLA.0000000000002168","article-title":"Laparoscopy-assisted versus open D2 distal gastrectomy for advanced gastric cancer: results from a randomized phase II multicenter clinical trial (COACT 1001)","volume":"267","author":"YK Park","year":"2018","journal-title":"Ann Surg"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1001\/jamasurg.2019.3473","article-title":"Assessment of laparoscopic distal gastrectomy after neoadjuvant chemotherapy for locally advanced gastric cancer. A randomized clinical trial","volume":"154","author":"Z Li","year":"2019","journal-title":"JAMA Surg"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s00464-018-6391-x","article-title":"Short-term surgical outcomes of laparoscopy-assisted versus open D2 distal gastrectomy for locally advanced gastric cancer in North China: a multicenter randomized controlled trial","volume":"33","author":"Z Wang","year":"2019","journal-title":"Surg Endosc"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"3304","DOI":"10.1200\/JCO.20.01210","article-title":"Long-term outcomes of laparoscopic distal gastrectomy for locally advanced gastric cancer: the KLASS-02-RCT randomized clinical trial","volume":"38","author":"WJ Hyung","year":"2020","journal-title":"J Clin Oncol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1245\/s10434-019-07688-y","article-title":"Short-term outcomes of laparoscopic and open total gastrectomy for gastric cancer: a nationwide retrospective cohort analysis","volume":"27","author":"T Sakamoto","year":"2020","journal-title":"Ann Surg Oncol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1097\/SLA.0000000000002391","article-title":"Postoperative outcomes of minimally invasive gastrectomy versus open gastrectomy during the early introduction of minimally invasive gastrectomy in the Netherlands: a population-based cohort study","volume":"266","author":"HJF Brenkman","year":"2017","journal-title":"Ann Surg"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"2218","DOI":"10.1245\/s10434-009-0508-3","article-title":"Totally laparoscopic gastric resection with extended lymphadenectomy for gastric adenocarcinoma","volume":"16","author":"EA Guzman","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"4267","DOI":"10.1007\/s00464-013-3037-x","article-title":"Long-term outcomes of laparoscopy-assisted distal gastrectomy for early gastric cancer: result of a randomized controlled trial (COACT 0301)","volume":"27","author":"YW Kim","year":"2013","journal-title":"Surg Endosc"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"245","DOI":"10.4174\/jkss.2011.80.4.245","article-title":"The effects of laparoscopic assisted total gastrectomy on surgical outcomes in the treatment of gastric cancer","volume":"80","author":"MG Kim","year":"2011","journal-title":"J Korean Surg Soc"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1097\/01.sle.0000191589.84485.4a","article-title":"Laparoscopy-assisted total gastrectomy for early gastric cancer: comparison with conventional open total gastrectomy","volume":"15","author":"S Usui","year":"2005","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"9656","DOI":"10.3748\/wjg.v21.i32.9656","article-title":"Systematic review of anastomotic complications of esophagojejunostomy after laparoscopic total gastrectomy","volume":"21","author":"M Inokuchi","year":"2015","journal-title":"World J Gastroenterol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1007\/s00464-007-9549-5","article-title":"Determinants of complications and adequacy of surgical resection in laparoscopic versus open total gastrectomy for adenocarcinoma","volume":"22","author":"B Topal","year":"2008","journal-title":"Surg Endosc"},{"key":"ref27","first-page":"243","article-title":"Laparoscopic versus open gastrectomy for adenocarcinoma: a prospective comparative analysis","volume":"65","author":"E Chouillard","year":"2010","journal-title":"Minerva Chir"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s10120-016-0687-0","article-title":"Long-term outcomes of laparoscopy-assisted distal gastrectomy with suprapancreatic nodal dissection for clinical stage I gastric cancer: a multicenter phase II trial (JCOG0703)","volume":"21","author":"N Hiki","year":"2018","journal-title":"Gastric Cancer"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"123","DOI":"10.4174\/jkss.2013.84.2.123","article-title":"Prospective randomized controlled trial (phase III) to comparing laparoscopic distal gastrectomy with open distal gastrectomy for gastric adenocarcinoma (KLASS 01)","volume":"84","author":"HH Kim","year":"2013","journal-title":"J Korean Surg Soc"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1997","DOI":"10.1007\/s00464-008-0015-9","article-title":"Laparoscopically assisted total gastrectomy with lymph node dissection for upper and middle gastric cancer","volume":"22","author":"E Mochiki","year":"2008","journal-title":"Surg Endosc"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1500","DOI":"10.1002\/bjs.9902","article-title":"Comparison of outcomes after laparoscopy-assisted and open total gastrectomy for early gastric cancer","volume":"102","author":"JH Lee","year":"2015","journal-title":"BJS"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"2734","DOI":"10.1007\/s00268-015-3160-z","article-title":"A multi-institutional, prospective, phase II feasibility study of laparoscopy-assisted distal gastrectomy with D2 lymph node dissection for locally advanced gastric cancer (JLSSG0901)","volume":"39","author":"N Inaki","year":"2015","journal-title":"World J Surg"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1001\/jama.2019.5359","article-title":"Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer: the CLASS-01 randomized clinical trial","volume":"321","author":"J Yu","year":"2019","journal-title":"JAMA"},{"key":"ref34","first-page":"146","article-title":"Laparoscopy-assisted Billroth I gastrectomy","volume":"4","author":"S Kitano","year":"1994","journal-title":"Surg Laparosc Endosc"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1007\/s00464-017-5730-7","article-title":"Long- and short-term outcomes of laparoscopic gastrectomy versus open gastrectomy in patients with clinically and pathological locally advanced gastric cancer: a propensity-score matching analysis","volume":"32","author":"M Inokuchi","year":"2018","journal-title":"Surg Endosc"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1055\/a-0586-9275","article-title":"Laparoskopische vs. konventionell-offene D2-Gastrektomie bei Magenkarzinom: eine Matched-Pair-Analyse","volume":"143","author":"K Ludwig","year":"2018","journal-title":"Zentralbl Chir"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1089\/lap.2012.0310","article-title":"Totally laparoscopic versus open gastrectomy for gastric cancer: a matched cohort study","volume":"23","author":"F Cianchi","year":"2013","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1002\/jso.21554","article-title":"Assessment of open versus laparoscopy-assisted gastrectomy in lymph node-positive early gastric cancer: a retrospective cohort analysis","volume":"102","author":"JY An","year":"2010","journal-title":"J Surg Oncol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1016\/S0140-6736(17)33326-3","article-title":"Global surveillance of trends in cancer survival 2000\u201314 (CONCORD-3): analysis of individual records for 37\u2008513\u2008025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries","volume":"391","author":"C Allemani","year":"2018","journal-title":"Lancet"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1097\/SLA.0b013e3181d3d29b","article-title":"Comparison of gastric cancer survival following R0 resection in the United States and Korea using an internationally validated nomogram","volume":"251","author":"VE Strong","year":"2010","journal-title":"Ann Surg"},{"key":"ref41","first-page":"319","article-title":"Completely laparoscopic versus open total gastrectomy in stage I-III\/C gastric cancer: safety, efficacy and five-year oncologic outcome","volume":"67","author":"LM Siani","year":"2012","journal-title":"Minerva Chir"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.amjsurg.2013.09.028","article-title":"Comparison of long-term results between laparoscopy-assisted gastrectomy and open gastrectomy with D2 lymphadenectomy for advanced gastric cancer","volume":"208","author":"C Fang","year":"2014","journal-title":"Am J Surg"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1007\/s00464-012-2442-x","article-title":"Laparoscopic versus open D2 gastrectomy for advanced gastric cancer: a retrospective cohort study","volume":"27","author":"T Shinohara","year":"2013","journal-title":"Surg Endosc"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1097\/SLA.0000000000002768","article-title":"Long-term outcomes of laparoscopic versus open surgery for clinical stage II\/III gastric cancer: a multicenter cohort study in Japan (LOC-A Study)","volume":"269","author":"T Kinoshita","year":"2019","journal-title":"Ann Surg"}],"container-title":["Zentralblatt f\u00fcr Chirurgie - Zeitschrift f\u00fcr Allgemeine, Viszeral-, Thorax- und Gef\u00e4\u00dfchirurgie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2258-0298.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T16:45:10Z","timestamp":1730825110000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2258-0298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,28]]},"references-count":43,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2024,4,2]]},"published-print":{"date-parts":[[2024,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2258-0298","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0044-409X","1438-9592"],"issn-type":[{"type":"print","value":"0044-409X"},{"type":"electronic","value":"1438-9592"}],"subject":[],"published":{"date-parts":[[2024,2,28]]}}}