{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T22:47:55Z","timestamp":1789080475979,"version":"build-2803163510"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Surgical mitral valve repair is the gold standard treatment of severe primary mitral regurgitation (MR). In the light of rapidly evolving percutaneous technologies, current surgical outcome data are essential to support heart-team-based decision-making.<\/jats:p><jats:p>\n          Methods\u2003This retrospective, high-volume, single-center study analyzed in 1779 patients with primary MR early morbidity and mortality, postoperative valve function, and long-term survival after mitral valve (MV) repair. Surgeries were performed between 2009 and 2022. Surgical approaches included full sternotomy (FS) and right-sided minithoracotomy (minimally invasive cardiac [MIC] surgery).<\/jats:p><jats:p>\n          Results\u2003Of the surgeries (mean age: 59.9 [standard deviation:11.4] years; 71.5% males), 85.6% (n\u2009=\u20091,527) were minithoracotomies. Concomitant procedures were performed in 849 patients (47.7%), including tricuspid valve and\/or atrial septal defect repair, cryoablation, and atrial appendage closure. The majority of patients did not need erythrocyte concentrates. Mediastinitis and rethoracotomy for bleeding rates were 0.1 and 4.3%, respectively. Reoperation before discharge for failed repair was necessary in 12 patients (0.7%). Freedom from more than moderate MR was\u2009&gt;\u200999%. Thirty-day mortality was 0.2% and did not differ significantly between groups (p\u2009=\u20090.37). Median follow-up was 48.2 months with a completeness of 95.9%. Long-term survival was similar between groups (p\u2009=\u20090.21). In the FS and MIC groups, 1-, 5-, and 10-year survival rates were 98.8 and 98.8%, 92.9 and 94.4%, and 87.4 and 83.1%, respectively.<\/jats:p><jats:p>\n          Conclusion\u2003MV surgery, both minimally invasive and via sternotomy, is associated with high repair rates, excellent perioperative outcomes, and long-term survival. Data underscore the effectiveness of surgical repair in managing MR, even in the era of advancing interventional techniques.<\/jats:p>","DOI":"10.1055\/a-2266-7677","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T00:49:52Z","timestamp":1707785392000},"page":"624-630","source":"Crossref","is-referenced-by-count":4,"title":["Early and Late Results after Surgical Mitral Valve Repair: A High-Volume Center Experience"],"prefix":"10.1055","volume":"72","author":[{"given":"Julia","family":"G\u00f6tte","sequence":"additional","affiliation":[{"name":"Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6085-6554","authenticated-orcid":false,"given":"Armin","family":"Zittermann","sequence":"additional","affiliation":[{"name":"Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus-Andre","family":"Deutsch","sequence":"additional","affiliation":[{"name":"Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene","family":"Schramm","sequence":"additional","affiliation":[{"name":"Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Bleiziffer","sequence":"additional","affiliation":[{"name":"Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Renner","sequence":"additional","affiliation":[{"name":"Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan F.","family":"Gummert","sequence":"additional","affiliation":[{"name":"Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"issue":"13","key":"ref1","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0195-668X(03)00201-X","article-title":"A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on Valvular Heart Disease","volume":"24","author":"B Iung","year":"2003","journal-title":"Eur Heart J"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S0002-9149(00)01362-X","article-title":"Prevalence and correlates of mitral regurgitation in a population-based sample (the Strong Heart Study)","volume":"87","author":"E C Jones","year":"2001","journal-title":"Am J Cardiol"},{"issue":"36","key":"ref3","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"38","author":"H Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"issue":"19","key":"ref4","first-page":"2421","article-title":"2017 ACC expert consensus decision pathway on the management of mitral regurgitation: a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways","volume":"70","author":"P T O'Gara","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"ref5","first-page":"1022","article-title":"2020 ACC\/AHA guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"91","author":"C M Otto","year":"1995","journal-title":"Circulation"},{"issue":"20","key":"ref6","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1016\/j.jcin.2020.06.053","article-title":"Transcatheter edge-to-edge mitral valve repair with the MitraClip G4 system","volume":"13","author":"T Chakravarty","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"issue":"05","key":"ref9","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1055\/s-0043-1769597","article-title":"German Heart Surgery Report 2022: the Annual Updated Registry of the German Society for Thoracic and Cardiovascular Surgery","volume":"71","author":"A Beckmann","year":"2023","journal-title":"Thorac Cardiovasc Surg"},{"issue":"07","key":"ref10","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jacc.2022.11.017","article-title":"Risk of surgical mitral valve repair for primary mitral regurgitation","volume":"81","author":"V Badhwar","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.xjon.2022.11.004","article-title":"Contemporary outcomes of mitral valve repair for degenerative disease in the era of increased penetrance of percutaneous mitral valve technology","volume":"13","author":"B G Abt","year":"2022","journal-title":"JTCVS Open"},{"issue":"08","key":"ref12","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jacc.2019.06.052","article-title":"Long-term results of mitral valve repair for regurgitation due to leaflet prolapse","volume":"74","author":"T E David","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"05","key":"ref13","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.athoracsur.2021.08.083","article-title":"Robotic mitral valve repair: a decade of experience with echocardiographic follow-up","volume":"114","author":"A Arghami","year":"2022","journal-title":"Ann Thorac Surg"},{"issue":"01","key":"ref14","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/icvts\/ivu337","article-title":"Early and mid-term clinical outcome in younger and elderly patients undergoing mitral valve repair with or without tricuspid valve repair","volume":"20","author":"A Renner","year":"2015","journal-title":"Interact Cardiovasc Thorac Surg"},{"issue":"03","key":"ref15","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jacl.2018.03.079","article-title":"Vitamin D supplementation and lipoprotein metabolism: a randomized controlled trial","volume":"12","author":"V Schwetz","year":"2018","journal-title":"J Clin Lipidol"},{"issue":"14","key":"ref16","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1161\/CIRCULATIONAHA.112.000699","article-title":"Late outcomes of mitral valve repair for mitral regurgitation due to degenerative disease","volume":"127","author":"T E David","year":"2013","journal-title":"Circulation"},{"issue":"02","key":"ref17","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1055\/s-0040-1716324","article-title":"Long-term clinical outcome in elderly patients undergoing mitral valve repair","volume":"70","author":"J G\u00f6tte","year":"2022","journal-title":"Thorac Cardiovasc Surg"},{"issue":"02","key":"ref18","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.athoracsur.2022.05.057","article-title":"Outcomes of mitral valve repair among high- and low-volume surgeons within a high-volume institution","volume":"115","author":"P Newell","year":"2023","journal-title":"Ann Thorac Surg"},{"issue":"10","key":"ref19","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/jamacardio.2020.2221","article-title":"Volume-outcome association of mitral valve surgery in the United States","volume":"5","author":"V Badhwar","year":"2020","journal-title":"JAMA Cardiol"},{"key":"ref20","first-page":"S0735","article-title":"Relation of mitral valve surgery volume to repair rate, durability, and survival","author":"J Chikwe","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"20","key":"ref21","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1001\/jama.2023.7089","article-title":"Transcatheter mitral valve repair for degenerative mitral regurgitation","volume":"329","author":"R R Makkar","year":"2023","journal-title":"JAMA"},{"issue":"25","key":"ref22","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1016\/j.jacc.2015.10.018","article-title":"Randomized comparison of percutaneous repair and surgery for mitral regurgitation: 5-year results of EVEREST II","volume":"66","author":"T Feldman","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"04","key":"ref23","doi-asserted-by":"crossref","first-page":"e027504","DOI":"10.1161\/JAHA.122.027504","article-title":"Percutaneous MitraClip device or surgical mitral valve repair in patients with primary mitral regurgitation who are candidates for surgery: design and rationale of the REPAIR MR trial","volume":"12","author":"P M McCarthy","year":"2023","journal-title":"J Am Heart Assoc"},{"issue":"01","key":"ref24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2021.04.062","article-title":"Mitral surgery after transcatheter edge-to-edge repair: Society of Thoracic Surgeons database analysis","volume":"78","author":"J Chikwe","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"03","key":"ref25","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.athoracsur.2018.03.086","article-title":"Isolated mitral valve surgery: the Society of Thoracic Surgeons adult cardiac surgery database analysis","volume":"106","author":"J S Gammie","year":"2018","journal-title":"Ann Thorac Surg"},{"issue":"03","key":"ref26","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.jtcvs.2017.01.047","article-title":"Outcomes after mitral valve repair: a single-center 16-year experience","volume":"154","author":"J M Tatum","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"01","key":"ref27","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.athoracsur.2021.07.060","article-title":"Durable robotic mitral repair of degenerative primary regurgitation with long-term follow-up","volume":"114","author":"A Roach","year":"2022","journal-title":"Ann Thorac Surg"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2266-7677.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T23:43:08Z","timestamp":1732664588000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2266-7677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,12]]},"references-count":25,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2024,11,26]]},"published-print":{"date-parts":[[2024,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2266-7677","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"value":"0171-6425","type":"print"},{"value":"1439-1902","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,2,12]]},"published":{"date-parts":[[2024,2,12]]}}}