{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T05:30:34Z","timestamp":1730871034512,"version":"3.28.0"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The rationale of the study was to analyze the impact of age on quality of life (QoL) in patients who had undergone cardiac surgery with consecutive extracorporeal life support (ECLS) treatment.<\/jats:p><jats:p>\n          Methods\u2003The study population consisted of 200 patients, operated upon between August 2006 and December 2018. The patient cohort was divided into two groups following an arbitrary cutoff age of 70 years. Comparative outcome analysis was calculated utilizing the European Quality of Life-5-Dimensions-5-Level Version (EQ-5D-5L).<\/jats:p><jats:p>\n          Results\u2003A total of 113 patients were 70 years or less old (group young), whereas 87 patients were older than 70 years (group old). In 45.7% of cases, the ECLS system was established during cardiogenic shock and external cardiac massage. The overall survival-to-discharge was 31.5% (n\u2009=\u200963), with a significantly better survival in the younger patient group (young\u2009=\u200938.9%; old\u2009=\u200921.8%, p\u2009=\u20090.01). Forty-two patients (66%) responded to the QoL survey after a median follow-up of 4.3 years. Older patients reported more problems with mobility (y\u2009=\u200952%; o\u2009=\u200988%, p\u2009=\u20090.02) and self-care (y\u2009=\u200924%; o\u2009=\u200976%, p\u2009=\u20090.01). However, the patients' self-rated health status utilizing the Visual Analogue Scale revealed no differences (y\u2009=\u200970% [50\u201380%]; o\u2009=\u200970% [60\u201380%], p\u2009=\u20090.38). Likewise, the comparison with an age-adjusted German reference population revealed similar QoL indices. There were no statistically significant differences in the EQ-5D-5L index values related to sex, number of comorbidities, and emergency procedures.<\/jats:p><jats:p>\n          Conclusion\u2003Despite the limited sample size due to the high mortality rate especially in elderly, the present study suggests that QoL of elderly patients surviving ECLS treatment is almost comparable to younger patients.<\/jats:p>","DOI":"10.1055\/a-2272-6343","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T23:55:28Z","timestamp":1708473328000},"page":"530-538","source":"Crossref","is-referenced-by-count":0,"title":["Age-Related Quality of Life in Cardiac Surgical Patients with Extracorporeal Life Support"],"prefix":"10.1055","volume":"72","author":[{"given":"Jes\u00fas A.","family":"Terrazas","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea C.","family":"Stadlbauer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Bitzinger","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudius","family":"Diez","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christof","family":"Schmid","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Camboni","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,5,10]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1055\/s-0043-1769597","article-title":"German Heart Surgery Report 2022: The Annual Updated Registry of the German Society for Thoracic and Cardiovascular Surgery","volume":"71","author":"A Beckmann","year":"2023","journal-title":"Thorac Cardiovasc Surg"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1161\/CIRCULATIONAHA.106.666289","article-title":"A decade of short-term outcomes in post cardiac surgery ventricular assist device implantation: data from the Society of Thoracic Surgeons' National Cardiac Database","volume":"116","author":"A F Hernandez","year":"2007","journal-title":"Circulation"},{"issue":"02","key":"ref3","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/S0003-4975(01)03330-6","article-title":"Extracorporeal membrane oxygenation support for adult postcardiotomy cardiogenic shock","volume":"73","author":"W-J Ko","year":"2002","journal-title":"Ann Thorac Surg"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/S0003-4975(00)02504-2","article-title":"An extracorporeal membrane oxygenation-based approach to cardiogenic shock in an older population","volume":"71","author":"C Smith","year":"2001","journal-title":"Ann Thorac Surg"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jtcvs.2007.08.007","article-title":"Venoarterial extracorporeal membrane oxygenation for treatment of cardiogenic shock: clinical experiences in 45 adult patients","volume":"135","author":"F Bakhtiary","year":"2008","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"04","key":"ref6","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ejcts.2006.07.016","article-title":"Creatine kinase isoenzyme MB relative index as predictor of mortality on extracorporeal membrane oxygenation support for postcardiotomy cardiogenic shock in adult patients","volume":"30","author":"R Zhang","year":"2006","journal-title":"Eur J Cardiothorac Surg"},{"issue":"03","key":"ref7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/icvts\/ivx155","article-title":"Clinical outcomes in patients after extracorporeal membrane oxygenation support for post-cardiotomy cardiogenic shock: a single-centre experience of 92 cases","volume":"25","author":"J Guihaire","year":"2017","journal-title":"Interact Cardiovasc Thorac Surg"},{"issue":"04","key":"ref8","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1177\/0267659118815291","article-title":"Long-term quality of life in patients treated with extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock","volume":"34","author":"I Norkiene","year":"2019","journal-title":"Perfusion"},{"issue":"05","key":"ref9","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1097\/CCM.0b013e31816f7cf7","article-title":"Outcomes and long-term quality-of-life of patients supported by extracorporeal membrane oxygenation for refractory cardiogenic shock","volume":"36","author":"A Combes","year":"2008","journal-title":"Crit Care Med"},{"issue":"06","key":"ref10","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1007\/s11136-021-03007-9","article-title":"Feasibility of the EQ-5D in the elderly population: a systematic review of the literature","volume":"31","author":"O Marten","year":"2022","journal-title":"Qual Life Res"},{"issue":"03","key":"ref11","doi-asserted-by":"crossref","first-page":"S148","DOI":"10.1097\/00005650-198903001-00012","article-title":"Quality of life, health status, and clinical research","volume":"27","author":"M Bergner","year":"1989","journal-title":"Med Care"},{"issue":"03","key":"ref12","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/0885-3924(94)90129-5","article-title":"Quality of life: concepts and definition","volume":"9","author":"D F Cella","year":"1994","journal-title":"J Pain Symptom Manage"},{"issue":"06","key":"ref13","first-page":"957","article-title":"Definition and measurement of quality of life in oncology nursing research: review and theoretical implications","volume":"22","author":"M E Mast","year":"1995","journal-title":"Oncol Nurs Forum"},{"issue":"08","key":"ref14","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1001\/jama.1994.03520080061045","article-title":"A critical appraisal of the quality of quality-of-life measurements","volume":"272","author":"T M Gill","year":"1994","journal-title":"JAMA"},{"issue":"01","key":"ref15","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1186\/s12889-019-7623-2","article-title":"Quality of life assessment in patients with heart failure: validity of the German version of the generic EQ-5D-5L\u2122","volume":"19","author":"S Boczor","year":"2019","journal-title":"BMC Public Health"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.resuscitation.2015.05.021","article-title":"Clinical course and long-term outcome following venoarterial extracorporeal life support-facilitated interhospital transfer of patients with circulatory failure","volume":"93","author":"S Schopka","year":"2015","journal-title":"Resuscitation"},{"issue":"04","key":"ref17","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jval.2016.01.003","article-title":"Dutch tariff for the five-level version of EQ-5D","volume":"19","author":"M M Versteegh","year":"2016","journal-title":"Value Health"},{"issue":"06","key":"ref19","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s40273-018-0615-8","article-title":"German value set for the EQ-5D-5L","volume":"36","author":"K Ludwig","year":"2018","journal-title":"PharmacoEconomics"},{"issue":"01","key":"ref20","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12955-021-01719-7","article-title":"EQ-5D-5L reference values for the German general elderly population","volume":"19","author":"O Marten","year":"2021","journal-title":"Health Qual Life Outcomes"},{"issue":"06","key":"ref21","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s10198-019-01054-1","article-title":"Health-related quality of life measured with the EQ-5D-5L: estimation of normative index values based on a representative German population sample and value set","volume":"20","author":"T Grochtdreis","year":"2019","journal-title":"Eur J Health Econ"},{"issue":"03","key":"ref22","doi-asserted-by":"crossref","first-page":"343","DOI":"10.3390\/ijerph13030343","article-title":"EQ-5D-5L in the general German population: comparison and evaluation of three yearly cross-section surveys","volume":"13","author":"M B Huber","year":"2016","journal-title":"Int J Environ Res Public Health"},{"issue":"14","key":"ref23","doi-asserted-by":"crossref","first-page":"e029609","DOI":"10.1161\/JAHA.123.029609","article-title":"Patient and management variables associated with survival after postcardiotomy extracorporeal membrane oxygenation in adults: the PELS-1 multicenter cohort study","volume":"12","author":"S Mariani","year":"2023","journal-title":"J Am Heart Assoc"},{"issue":"01","key":"ref24","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s13019-017-0618-0","article-title":"Extra-corporeal membrane oxygenation for refractory cardiogenic shock after adult cardiac surgery: a systematic review and meta-analysis","volume":"12","author":"M Khorsandi","year":"2017","journal-title":"J Cardiothorac Surg"},{"issue":"01","key":"ref25","doi-asserted-by":"crossref","first-page":"116","DOI":"10.21037\/acs.2018.12.04","article-title":"Long-term survival and major outcomes in post-cardiotomy extracorporeal membrane oxygenation for adult patients in cardiogenic shock","volume":"8","author":"P Meani","year":"2019","journal-title":"Ann Cardiothorac Surg"},{"issue":"02","key":"ref26","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jtcvs.2009.10.043","article-title":"Early and late outcomes of 517 consecutive adult patients treated with uardiotomy cardiogenic shock","volume":"139","author":"A J Rastan","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"04","key":"ref27","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.athoracsur.2019.04.063","article-title":"Postcardiotomy venoarterial extracorporeal membrane oxygenation in patients aged 70 years or older","volume":"108","author":"F Biancari","year":"2019","journal-title":"Ann Thorac Surg"},{"issue":"05","key":"ref28","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1093\/ejcts\/ezac035","article-title":"Fate of patients weaned from post-cardiotomy extracorporeal life support","volume":"61","author":"A K Schaefer","year":"2022","journal-title":"Eur J Cardiothorac Surg"},{"issue":"02","key":"ref29","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.jtcvs.2017.02.055","article-title":"Long-term outcomes of extracorporeal membrane oxygenation support for postcardiotomy shock","volume":"154","author":"S-W Chen","year":"2017","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2272-6343.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T17:13:50Z","timestamp":1730826830000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2272-6343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,20]]},"references-count":28,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2024,10,8]]},"published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2272-6343","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"type":"print","value":"0171-6425"},{"type":"electronic","value":"1439-1902"}],"subject":[],"published-other":{"date-parts":[[2024,2,20]]},"published":{"date-parts":[[2024,2,20]]}}}