{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T19:16:08Z","timestamp":1776539768243,"version":"3.51.2"},"reference-count":44,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T00:00:00Z","timestamp":1713830400000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Entwickelt sich ein Glaukomschaden trotz eines v\u00f6llig normalen Augendruckes oder schreitet der Schaden trotz gut eingestellten Augendruckes weiter voran, dann finden wir meist andere Risikofaktoren. Eine wichtige Gruppe sind die vaskul\u00e4ren Faktoren. Dabei sollten wir uns nicht nur auf die klassischen Risikofaktoren der Arteriosklerose, wie die arterielle Hypertonie oder die Dyslipid\u00e4mie fokussieren, sondern auch auf Fehlregulationen der Durchblutung, insbesondere auf die prim\u00e4re vaskul\u00e4re Dysregulation (PVD). Ein tiefer Blutdruck, jetzt oder in der Jugend, ein niedriger Body-Mass-Index oder oft kalte H\u00e4nde und F\u00fc\u00dfe geben wichtige Hinweise. Sehr oft ist eine PVD gekoppelt mit einer Reihe von anderen Symptomen und Zeichen, dann sprechen wir von einem Flammer-Syndrom (FS). Bei Hinweisen auf ein FS machen wir eine gezielte Anamnese, eine 24-h-Blutdruckmessung, eine Messung des retinalen Venendruckes, eine dynamische retinale Gef\u00e4\u00dfanalyse oder eine Nagelfalz-Kapillarmikroskopie.\n          Das empfiehlt sich insbesondere dann, wenn der Patient noch relativ jung ist oder der Schaden rasch fortschreitet. Erh\u00e4rtet sich der Verdacht, dann versuchen wir, die Blutdruckabf\u00e4lle zu vermindern, den retinalen Venendruck zu senken, die Regulation der Durchblutung zu verbessern und den oxidativen Stress in den Mitochondrien zu reduzieren.<\/jats:p>","DOI":"10.1055\/a-2275-2323","type":"journal-article","created":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T22:51:25Z","timestamp":1713912685000},"page":"355-360","source":"Crossref","is-referenced-by-count":1,"title":["Glaukompatient mit Verdacht auf Flammer-Syndrom: diagnostische Schritte und therapeutische Konsequenzen"],"prefix":"10.1055","volume":"241","author":[{"given":"Katarzyna","family":"Konieczka","sequence":"additional","affiliation":[{"name":"Praxis Dr. med. K. Konieczka, speziell Glaukom, Mittlere Strasse 28, 4056 Basel"},{"name":"Augenklinik, Universit\u00e4tsspital Basel, Mittlere Strasse 91, 4056 (Vorsitzender: Prof. Dr. med. N. 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