{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T13:10:03Z","timestamp":1730812203443,"version":"3.28.0"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Gegenstand und Ziel Die Studie stellt den individuellen Verlauf der\n                    Konzentrationen von \u00d6stradiol-17\u00df und Progesteron im Blut von Stuten \u00fcber einen\n                    Zyklus dar, um auf physiologische individuelle Unterschiede zwischen einzelnen\n                    Tieren hinzuweisen und Interpretationshilfen von Hormonwerten zu geben.<\/jats:p><jats:p>\n          Material und Methoden An 7 Stuten wurde \u00fcber den Zyklusverlauf die\n                    Konzentrationen an Progesteron und \u00d6stradiol-17\u00df bestimmt. Eine Stute wurde\n                    aufgrund eines vom physiologischen Zyklus abweichenden Verlaufs aus der\n                    Beurteilung ausgeschlossen. Zus\u00e4tzlich wurden die Ovarien t\u00e4glich sonografisch\n                    untersucht, um die Hormonwerte morphologischen Ver\u00e4nderungen auf den Ovarien\n                    zuordnen zu k\u00f6nnen.<\/jats:p><jats:p>\n          Ergebnisse Teilweise zeigen Stuten erhebliche individuelle Unterschiede in\n                    ihren Hormonverl\u00e4ufen, die sich auch von den ver\u00f6ffentlichten Vergleichswerten\n                    in der Literatur unterscheiden. So zeigten 2 Stuten zum Zeitpunkt der Ovulation\n                    einen Progesteronwert oberhalb des Basalniveaus. Die postovulatorischen\n                    Progesteronverl\u00e4ufe der Stuten zeigen deutliche Schwankungen, was die Angabe von\n                    Referenzwerten in den verschiedenen Abschnitten der Gelbk\u00f6rperphase erschwert.\n                    Die L\u00e4nge der Plateauphasen betr\u00e4gt im Durchschnitt 12,3\u00b11,5 Tage. Die Stute mit\n                    der Doppelovulation zeigte die h\u00f6chsten Progesteronkonzentrationen.<\/jats:p><jats:p>\n          Schussfolgerung Die Messung von Plasmaprogesteronwerten bei Stuten sollten\n                    nur im Zusammenhang mit weiteren Untersuchungsergebnissen interpretiert werden.\n                    Die sehr starken Schwankungen der \u00d6stradiol-17\u00df-Konzentrationen machen es\n                    fraglich, ob die Bestimmung dieses Hormonwertes einen diagnostischen Nutzen\n                    hat.<\/jats:p><jats:p>\n          Klinische Relevanz Bei der Interpretation von Steroidhormonwerten im\n                    ingraviden Zyklus einer Stute sind die individuellen Verl\u00e4ufe zu beachten, die\n                    teilweise deutlich von den ver\u00f6ffentlichten Referenzwerten abweichen.<\/jats:p>","DOI":"10.1055\/a-2276-5226","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T22:32:41Z","timestamp":1714775561000},"page":"88-95","source":"Crossref","is-referenced-by-count":0,"title":["Individueller Konzentrationsverlauf von Progesteron und \u00d6stradiol-17\u03b2\n                    im Blut bei Stuten w\u00e4hrend des Zyklus"],"prefix":"10.1055","volume":"52","author":[{"given":"Sara","family":"Laufk\u00f6tter","sequence":"additional","affiliation":[{"name":"Tierklinik f\u00fcr Reproduktionsmedizin und Neugeborenenkunde,\n                    Justus-Liebig-Universit\u00e4t, Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"L\u00e4ngerer","sequence":"additional","affiliation":[{"name":"Tierklinik f\u00fcr Reproduktionsmedizin und Neugeborenenkunde,\n                    Justus-Liebig-Universit\u00e4t, Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Wehrend","sequence":"additional","affiliation":[{"name":"Tierklinik f\u00fcr Reproduktionsmedizin und Neugeborenenkunde,\n                    Justus-Liebig-Universit\u00e4t, Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,5,3]]},"reference":[{"volume-title":"Regulation der weiblichen Fortpflanzung. 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