{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:27Z","timestamp":1740126807127,"version":"3.37.3"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"10","funder":[{"name":"National Institute of Child Health and Human Development","award":["1R01HD077592"],"award-info":[{"award-number":["1R01HD077592"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>\n            Objective\u2003Oligohydramnios (defined as amniotic fluid volume\u2009&lt;\u20095\u2009cm or deepest vertical pocket\u2009&lt;\u20092\u2009cm) is regarded as an ominous finding on prenatal ultrasound. Amniotic fluid, however, is not static, and to date, there have been no studies comparing perinatal outcomes in patients who are diagnosed with oligohydramnios that resolves and those who have persistent oligohydramnios.<\/jats:p><jats:p>\n            Study Design\u2003This is a secondary analysis of a National Institutes of Health\u2013funded retrospective cohort study of singleton gestations delivered at a tertiary care hospital between 2002 and 2013 with mild hypertensive disorders and\/or fetal growth restriction (FGR). Maternal characteristics, delivery, and neonatal information were abstracted by trained research nurses. Patients with a diagnosis of oligohydramnios were identified, and those with resolved versus persistent oligohydramnios at the time of delivery were compared. The primary outcome was a composite of neonatal resuscitation at delivery: administration of oxygen, bag\u2013mask ventilation, continuous positive airway pressure, intubation, chest compression, or cardiac medication administration. Secondary outcomes included FGR, timing, and mode of delivery.<\/jats:p><jats:p>\n            Results\u2003Of 527 women meeting study criteria, 42 had oligohydramnios that resolved prior to delivery, whereas 485 had persistent oligohydramnios. There were no significant differences in patient demographics between groups. The gestational age at diagnosis was significantly lower for patients with resolved versus persistent oligohydramnios (median: 33.0 [interquartile range, IQR: 29.1\u201335.9] vs. 38.0 [IQR: 36.4\u201339.3], p\u2009&lt;\u20090.001). There was not a substantial difference in rate of neonatal resuscitation (41 vs. 32%, p\u2009=\u20090.31). Patients with resolved oligohydramnios were more likely to have developed FGR than those with persistent oligohydramnios (55 vs. 36%, p\u2009&lt;\u20090.02). There were no significant differences for gestational age at delivery, birth weight, or neonatal intensive care unit admission.<\/jats:p><jats:p>\n            Conclusion\u2003Patients whose oligohydramnios resolved were diagnosed earlier yet had similar rates of neonatal resuscitation but higher rates of FGR than those who had persistent oligohydramnios.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2278-8948","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T23:55:17Z","timestamp":1709250917000},"page":"1285-1289","source":"Crossref","is-referenced-by-count":0,"title":["Neonatal Outcomes Are Similar between Patients with Resolved and Those with Persistent Oligohydramnios"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9420-7456","authenticated-orcid":false,"given":"Anna R.","family":"Whelan","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Massachusetts Chan Medical School, Worcester, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phinnara","family":"Has","sequence":"additional","affiliation":[{"name":"Lifespan Health System, Department of Biostatistics, Epidemiology, and Research Design, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Savitz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island"},{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women & Infants Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8165-3457","authenticated-orcid":false,"given":"Valery A.","family":"Danilack","sequence":"additional","affiliation":[{"name":"Yale University, Department of Internal Medicine, Center for Outcomes Research and Evaluation, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam K.","family":"Lewkowitz","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women & Infants Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,3,26]]},"reference":[{"issue":"03","key":"ref1","first-page":"245","article-title":"Ultrasound evaluation of amniotic fluid volume. 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A case-control study","volume":"44","author":"S P Chauhan","year":"1999","journal-title":"J Reprod Med"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00404-006-0309-x","article-title":"Perinatal outcomes of pregnancies with borderline amniotic fluid index","volume":"276","author":"I I Gumus","year":"2007","journal-title":"Arch Gynecol Obstet"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1097\/EDE.0000000000001442","article-title":"Health outcomes associated with clinician-initiated delivery for hypertensive disorders at 34\u201338 weeks' gestation","volume":"33","author":"D A Savitz","year":"2022","journal-title":"Epidemiology"},{"issue":"04","key":"ref10","doi-asserted-by":"crossref","first-page":"B2","DOI":"10.1016\/j.ajog.2020.05.010","article-title":"Society for Maternal-Fetal Medicine consult series #52: diagnosis and management of fetal growth restriction: (Replaces Clinical Guideline Number 3, April 2012)","volume":"223","author":"J G Martins","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"17","key":"ref11","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1080\/14767058.2019.1566901","article-title":"Admission of full-term infants to the neonatal intensive care unit: a 9.5-year review in a tertiary teaching hospital","volume":"33","author":"X Yang","year":"2020","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"25","key":"ref12","doi-asserted-by":"crossref","first-page":"8666","DOI":"10.1080\/14767058.2021.1995858","article-title":"Adverse perinatal outcomes in fetuses with severe late-onset fetal growth restriction","volume":"35","author":"M LR Bahia","year":"2022","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"04","key":"ref13","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1055\/s-2007-972926","article-title":"Intrauterine growth restriction and oligohydramnios among high-risk patients","volume":"24","author":"S P Chauhan","year":"2007","journal-title":"Am J Perinatol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2278-8948.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T15:48:36Z","timestamp":1730821716000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2278-8948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,29]]},"references-count":13,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,7,4]]},"published-print":{"date-parts":[[2024,7]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2278-8948","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"type":"print","value":"0735-1631"},{"type":"electronic","value":"1098-8785"}],"subject":[],"published-other":{"date-parts":[[2024,2,29]]},"published":{"date-parts":[[2024,2,29]]}}}