{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T10:31:08Z","timestamp":1778063468093,"version":"3.51.4"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hamostaseologie"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>May\u2013Thurner syndrome (MTS) is a pelvic venous disorder involving compression of the left common iliac vein by the right common iliac artery, which results in predisposition for deep vein thrombosis. Although MTS is increasingly recognized in young patients, specific guidelines on diagnosis and management for children, adolescents, and young adults do not exist so far. The aim of this study was to assess current diagnostic and therapeutic practice in Germany, Austria, and Switzerland in children and young adults with thrombosis and MTS.<\/jats:p>\n                  <jats:p>We designed an online survey with 11 questions, which we sent via a mailing list to all members of the German, Austrian, and Swiss Society of Thrombosis and Haemostasis Research. Between July and October 2022, 33 specialists answered the questionnaire. Most participating specialists worked at pediatric hospitals (61%). Numbers of annually treated thromboses ranged from &lt;5 (26%) to &gt;30 (13%). Most specialists used venous ultrasound to diagnose deep vein thrombosis, 53% magnetic resonance imaging. Only 25% of specialists systematically screened for MTS in deep vein thrombosis. MTS was managed with anticoagulation (65%), iliac vein stent placement (32%), or balloon angioplasty (13%). In total, 31% of specialists reported to use more than one therapeutic method. Diagnostic and therapeutic approaches for MTS differed between specialists. Lack of standardization resulted in individualized and highly diverse management. Prospective observational clinical studies investigating the outcome of different management strategies including long-term follow-up on outcome and incidence of postthrombotic syndrome will help in defining patient groups who benefit most from revascularizing interventional strategies and developing standardized guidelines.<\/jats:p>","DOI":"10.1055\/a-2282-4565","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T19:14:58Z","timestamp":1719429298000},"page":"127-135","source":"Crossref","is-referenced-by-count":2,"title":["Current Diagnostic and Therapeutic Approaches in May\u2013Thurner Syndrome in Children, Adolescents, and Young Adults: A Survey among Thrombosis Experts of the German Society of Thrombosis and Haemostasis"],"prefix":"10.1055","volume":"46","author":[{"given":"Franziska","family":"Cuntz","sequence":"additional","affiliation":[{"name":"Department of Paediatric Oncology and Haematology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Gebauer","sequence":"additional","affiliation":[{"name":"Department of Radiology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Greiner","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikola","family":"Hagedorn","sequence":"additional","affiliation":[{"name":"Department of Paediatric Oncology and Haematology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madlen","family":"Reschke","sequence":"additional","affiliation":[{"name":"Department of Paediatric Oncology and Haematology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Eberl","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, St\u00e4dtisches Klinikum Braunschweig, Braunschweig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Zieger","sequence":"additional","affiliation":[{"name":"Division of Paediatric Haematology and Oncology, Department of Paediatrics and Adolescent Medicine, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edelgard","family":"Lindhoff-Last","sequence":"additional","affiliation":[{"name":"Cardiology Angiology Centre Bethanien, CCB Vascular Centre, CCB Coagulation Centre, Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Holzhauer","sequence":"additional","affiliation":[{"name":"Department of Paediatric Oncology and Haematology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.jvsv.2020.12.084","article-title":"The Symptoms-Varices-Pathophysiology classification of pelvic venous disorders: a report of the American Vein & Lymphatic Society International Working Group on Pelvic Venous Disorders","volume":"9","author":"M H Meissner","year":"2021","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1177\/000331975700800505","article-title":"The cause of the predominantly 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