{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T18:51:02Z","timestamp":1772131862572,"version":"3.50.1"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"08","funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","award":["413635475"],"award-info":[{"award-number":["413635475"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n            Background\/Objectives Whether seasonality is a factor that influences the incidence of acute pancreatitis (AP) is an under-investigated area. If seasonal incidence peaks can be detected, specifically with regard to biliary pancreatitis, has so far been answered in contradictory ways in the literature.<\/jats:p><jats:p>\n            Methods All AP cases from two tertiary German referral centers were identified between 2016 and 2022 based on ICD-10 discharge codes. The \u03c72 test for goodness of fit was applied to test significant differences in monthly and seasonal distributions of AP admissions.<\/jats:p><jats:p>\n            Results In total, 3597 AP cases were included. We observed significantly more idiopathic and biliary cases in May to July (p-values 0.041 and 0.027, respectively). Furthermore, most drug-induced APs were identified during the winter months (p-value 0.006). Moreover, there was a significant peak of alcohol-induced pancreatitis in summer and fall (p-value 0.038).<\/jats:p><jats:p>\n            Conclusions Our data indicate a seasonal impact on AP incidences for certain etiologies.<\/jats:p>","DOI":"10.1055\/a-2293-7813","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T22:45:25Z","timestamp":1715813125000},"page":"1207-1210","source":"Crossref","is-referenced-by-count":2,"title":["The four seasons of pancreatitis \u2013 Etiology of acute pancreatitis during the course of the year"],"prefix":"10.1055","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6047-334X","authenticated-orcid":false,"given":"Simon","family":"Sirtl","sequence":"additional","affiliation":[{"name":"Department of Medicine II, LMU University Hospital, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Hohmann","sequence":"additional","affiliation":[{"name":"Department of Medicine II, LMU University Hospital, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Beyer","sequence":"additional","affiliation":[{"name":"Department of Medicine II, LMU University Hospital, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Hamm","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Centre Goettingen, Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albrecht","family":"Neesse","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Centre Goettingen, Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Ammer-Herrmenau","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Centre Goettingen, Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,5,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1053\/j.gastro.2021.09.043","article-title":"Global Incidence of Acute Pancreatitis Is Increasing Over Time: A Systematic Review and Meta-Analysis","volume":"162","author":"JP Iannuzzi","year":"2022","journal-title":"Gastroenterology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.hpb.2018.08.003","article-title":"A systematic review and meta-analysis of the aetiology of acute pancreatitis","volume":"21","author":"MB Zilio","year":"2019","journal-title":"HPB"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1093\/bjs\/znad318","article-title":"Prospective multicentre study of indications for surgery in patients with 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Keller","year":"2001","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1097\/MPA.0000000000001626","article-title":"Role of the Immune System and the Circadian Rhythm in the Pathogenesis of Chronic Pancreatitis: Establishing a Personalized Signature for Improving the Effect of Immunotherapies for Chronic Pancreatitis","volume":"49","author":"A Kessler","year":"2020","journal-title":"Pancreas"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"638","DOI":"10.3389\/fendo.2020.00638","article-title":"Circadian Genes as Therapeutic Targets in Pancreatic Cancer","volume":"11","author":"M Garc\u00eda-Costela","year":"2020","journal-title":"Front Endocrinol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1046\/j.1365-2796.1998.00383.x","article-title":"Seasonal changes in symptomatic duodenal ulcer activity in Taiwan: a comparison between subjects with and without haemorrhage","volume":"244","author":"CJ Tsai","year":"1998","journal-title":"J Intern Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"e25820","DOI":"10.1097\/MD.0000000000025820","article-title":"Seasonal variation of peptic ulcer disease, peptic ulcer bleeding, and acute pancreatitis","volume":"100","author":"JY Yoon","year":"2021","journal-title":"Medicine (Baltimore)"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"3328","DOI":"10.3748\/wjg.v10.i22.3328","article-title":"Seasonal variation in the onset of acute pancreatitis","volume":"10","author":"M Gallerani","year":"2004","journal-title":"World J Gastroenterol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1988","DOI":"10.26355\/eurrev_202002_20376","article-title":"Chronobiology of acute pancreatitis in a single Italian centre","volume":"24","author":"M Guarino","year":"2020","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1097\/MPA.0000000000000795","article-title":"Impact of Seasons and Festivals on the Onset of Acute Pancreatitis in Shanghai, China","volume":"46","author":"D Wu","year":"2017","journal-title":"Pancreas"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1097\/00006676-199805000-00001","article-title":"The calendar and acute pancreatitis","volume":"16","author":"PG Lankisch","year":"1998","journal-title":"Pancreas"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1080\/00365520310003499","article-title":"Alcoholic, but not biliary, pancreatitis varies seasonally in occurrence","volume":"38","author":"S R\u00e4ty","year":"2003","journal-title":"Scand J Gastroenterol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1111\/apt.12408","article-title":"The incidence of acute pancreatitis: impact of social deprivation, alcohol consumption, seasonal and demographic factors","volume":"38","author":"S Roberts","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1093\/alcalc\/agx005","article-title":"Acute Pancreatitis: Impact of Alcohol Consumption and Seasonal Factors","volume":"52","author":"S Bertilsson","year":"2017","journal-title":"Alcohol Alcohol Oxf Oxfs"},{"key":"ref18","first-page":"995","article-title":"Incidence of acute pancreatitis does not increase during Oktoberfest, but is higher than previously described in Germany","volume":"9","author":"V Phillip","year":"2011","journal-title":"Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc"}],"container-title":["Zeitschrift f\u00fcr 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