{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:25:16Z","timestamp":1788776716086,"version":"build-2803163510"},"reference-count":7,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>\n            Objective\u2003Hypertensive disorders of pregnancy (HDP) are common complications associated with severe maternal and neonatal morbidity. One goal of prenatal care, especially at term, is to screen for HDP. As treatment of HDP centers on delivery when appropriate, timely diagnosis is crucial. We postulated that reduced in-person visits during the coronavirus disease 2019 (COVID-19) pandemic may have resulted in delayed diagnosis of HDP with concomitant higher rates of maternal morbidity. We sought to investigate the prevalence of HDP during the COVID-19 pandemic, as well as median gestational age at time of delivery as compared with the prepandemic median.<\/jats:p><jats:p>\n            Study Design\u2003This was a retrospective cohort analysis comparing singleton deliveries at four large-volume hospitals during the COVID-19 pandemic (April\u2013July 2020 during a statewide \u201cstay-at-home\u201d order) to those in a pre-COVID era (April\u2013July 2019). Deliveries complicated by HDP were identified by International Classification of Disease, Tenth Revision codes. Rates of HDP and markers of severe disease were the primary outcomes compared between the groups; multivariate regression was used to calculate the odds ratio of severe disease among women with any diagnosis of HDP.<\/jats:p><jats:p>\n            Results\u2003The cohort included 9,974 deliveries: 5,011 in 2020 and 4,963 in 2019. Patient characteristics (age, body mass index, race, ethnicity, and insurance type) did not differ significantly between the groups. There was an increase in HDP during the COVID era (9.0 vs. 6.9%; p\u2009&lt;\u20090.01), which was significant even when controlling for patient parity (odds ratio = 1.41, 95% confidence interval: 1.20\u20131.66). Among women with HDP, gestational age at delivery did not differ between the cohorts, nor did the proportion of patients with severe disease.<\/jats:p><jats:p>\n            Conclusion\u2003We found a statistically significant increase in the rate of HDP during the COVID-19 pandemic. However, there was no change in the proportion of severe disease, suggesting that this increase did not significantly impact clinical morbidity.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2295-3543","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T23:58:57Z","timestamp":1711497537000},"page":"1463-1468","source":"Crossref","is-referenced-by-count":3,"title":["Increased Rates of Hypertensive Disorders of Pregnancy during the COVID-19 Pandemic"],"prefix":"10.1055","volume":"41","author":[{"given":"Colleen M.","family":"Sinnott","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor S.","family":"Freret","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5568-4444","authenticated-orcid":false,"given":"Mark A.","family":"Clapp","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Little","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine, Brigham and Women's Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1053\/j.semperi.2009.02.010","article-title":"The global impact of pre-eclampsia and eclampsia","volume":"33","author":"L Duley","year":"2009","journal-title":"Semin Perinatol"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1001\/jama.2020.15242","article-title":"Association between number of in-person health care visits and SARS-CoV-2 infection in obstetrical patients","volume":"324","author":"S C Reale","year":"2020","journal-title":"JAMA"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"769","DOI":"10.15585\/mmwr.mm6925a1","article-title":"Characteristics of women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status\u2014United States, January 22\u2013June 7, 2020","volume":"69","author":"S Ellington","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"06","key":"ref6","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1111\/jocs.14638","article-title":"Collateral damage of COVID-19 pandemic: delayed medical care","volume":"35","author":"S Masroor","year":"2020","journal-title":"J Card Surg"},{"issue":"24","key":"ref7","doi-asserted-by":"crossref","first-page":"9264","DOI":"10.3390\/ijerph17249264","article-title":"Parental hesitancy and concerns around accessing paediatric unscheduled healthcare during COVID-19: a cross-sectional survey","volume":"17","author":"E Nicholson","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"590406","DOI":"10.3389\/fneur.2020.590406","article-title":"Impact of Covid-19 on the behavior of community residents with suspected transient ischemic attack","volume":"11","author":"S Yao","year":"2020","journal-title":"Front Neurol"},{"issue":"08","key":"ref9","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1080\/17434440.2019.1640116","article-title":"Telemonitoring for hypertensive disease in pregnancy","volume":"16","author":"A Khalil","year":"2019","journal-title":"Expert Rev Med Devices"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2295-3543.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T10:06:18Z","timestamp":1730801178000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2295-3543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,26]]},"references-count":7,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,7,24]]},"published-print":{"date-parts":[[2024,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2295-3543","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,3,26]]},"published":{"date-parts":[[2024,3,26]]}}}