{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T05:44:06Z","timestamp":1749102246613,"version":"3.37.3"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Managing acute abdomen in very low birth weight (VLBW) and premature infants\n                    presents a diagnostic challenge, often necessitating a thorough assessment to\n                    discern underlying causes. Umbilical venous catheters (UVCs), commonly used in\n                    neonatal intensive care, are essential but not without risks. A 29-week\n                    premature male infant, born to a 23-year-old mother, was referred to our clinic\n                    on the 16th day of life with a suspected diagnosis of necrotizing\n                    enterocolitis (NEC). The infant had spent the first day intubated and received\n                    non-invasive respiratory support for 15 days. A 5 French UVC was inserted at the\n                        2nd hour of life, and by the 3rd day of life, the\n                    infant transitioned to minimal enteral feeding. Between the 12th and\n                        16th days of life, the infant initially diagnosed with NEC due to\n                    symptoms such as decreased stool passage and abdominal distension. The patient\n                    had been on a continuous course of antibiotic treatment throughout the entirety\n                    of his life, commencing on the very first day due to suspected early neonatal\n                    sepsis, followed by nosocomial sepsis during the hospitalization, and persisting\n                    with antibiotic therapy for suspected NEC. The case took a unique turn upon\n                    further evaluation after being referred to our unit. Despite a preliminary NEC\n                    diagnosis, further evaluation revealed umbilical catheter complications, leading\n                    to total parenteral nutrition extravasation. Removal of the catheter, drainage,\n                    and antibiotic adjustment resulted in improved clinical outcomes. In neonatal\n                    care, cautious management is vital when dealing with infants exhibiting\n                    abdominal symptoms. A nuanced approach, including differential diagnosis and\n                    careful antibiotic use, is essential.<\/jats:p>","DOI":"10.1055\/a-2295-5110","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T23:03:56Z","timestamp":1715036636000},"page":"454-457","source":"Crossref","is-referenced-by-count":1,"title":["Umbilical Catheter Extravasation Mimicking Necrotizing Enterocolitis\n                    in a Preterm Neonate: A Diagnostic Challenge"],"prefix":"10.1055","volume":"228","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9716-130X","authenticated-orcid":false,"given":"Co\u015fkun","family":"Arma\u011fan","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Neonatology, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tevfik","family":"\u00c7ap\u0131tl\u0131","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Pediatrics, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcls\u00fcm","family":"Dilmen","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Pediatrics, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saadet \u00c7a\u011fla","family":"Kefeli","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Pediatric Surgery, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oktay","family":"Ulusoy","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Pediatric Surgery, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Funda","family":"Erdo\u011fan","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Neonatology, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuray","family":"Duman","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Neonatology, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"\u00d6zkan","sequence":"additional","affiliation":[{"name":"Dokuz Eylul University Faculty of Medicine, Neonatology, Izmir,\n                    Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,5,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"513","DOI":"10.5152\/TurkArchPediatr.2021.21164","article-title":"Turkish Neonatal Society Necrotizing Enterocolitis Diagnosis, Treatment and\n                    Prevention Guidelines","volume":"56","author":"E Ergenekon","year":"2021","journal-title":"Turk Arch Pediatr"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1097\/jpn.0000000000000589","article-title":"Neonatal vascular access practice and complications: An observational study of\n                    1,375 catheter days","volume":"37","author":"C McIntyre","year":"2023","journal-title":"J Perinat Neonatal Nurs"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.pedneo.2019.05.004","article-title":"Hepatic extravasation complicated by umbilical venous catheterization in\n                    neonates: A 5-year, single-center experience","volume":"61","author":"H J Chen","year":"2020","journal-title":"Pediatr Neonatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1038\/s41467-022-28525-z","article-title":"Effects of early-life antibiotics on the developing infant gut microbiome and\n                    resistome: a randomized trial","volume":"13","author":"M Reyman","year":"2022","journal-title":"Nat Commun"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"CD012142","DOI":"10.1002\/14651858.CD012142.pub2","article-title":"Early planned removal of umbilical venous catheters to prevent infection in\n                    newborn infants","volume":"10","author":"A Gordon","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"e429","DOI":"10.5546\/aap.2016.eng.e429","article-title":"An umbilical venous catheter complication presented as acute abdomen: case\n                    report","volume":"114","author":"M O Oztan","year":"2016","journal-title":"Arch Argent Pediatr"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e7563","DOI":"10.1002\/ccr3.7563","article-title":"Point-of-care ultrasound aided diagnosis and management of peritoneal parenteral\n                    nutrition extravasation in a preterm baby: A case report","volume":"11","author":"A O Kowalczyk","year":"2023","journal-title":"Clin Case Rep"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"e090102","DOI":"10.7363\/090102","article-title":"Parenteral nutrition extravasation associated liver injury \u2013 A case series with\n                    varying clinical-radiological presentations","volume":"9","author":"V V Ramaswamy","year":"2019","journal-title":"J Pediatr Neonatal Individual Med (JPNIM)"},{"key":"ref9","first-page":"e35","article-title":"Intraperitoneal extravasation of total parental nutrition infusate from an\n                    umbilical venous catheter","volume":"49","author":"I Shareena","year":"2008","journal-title":"Singapore Med J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-226377","article-title":"Ascites with hepatic extravasation of total parenteral nutrition (TPN) secondary\n                    to umbilical venous catheter (UVC) malposition in an extremely preterm baby","volume":"2018","author":"S Pegu","year":"2018","journal-title":"BMJ Case Rep"},{"key":"ref11","first-page":"197","article-title":"Ascites in a premature baby due to parenteral nutrition from an umbilical venous\n                    catheter","volume":"36","author":"J Panetta","year":"2000","journal-title":"J Paediatr Child Health"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"77","DOI":"10.2147\/rm.s325774","article-title":"Acute management of intraperitoneal extravasation of total parenteral nutrition\n                    (TPN) in a very preterm \u0131nfant: case report and literature review","volume":"11","author":"A Majid","year":"2021","journal-title":"Res Rep Neonatol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1590\/s1516-31802002000200007","article-title":"Acute abdomen due to late retroperitoneal extravasation from a femoral venous\n                    catheter in a newborn","volume":"120","author":"J Sztajnbok","year":"2002","journal-title":"Sao Paulo Med J"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.anpedi.2015.10.011","volume-title":"Catheter tip position and risk of mechanical complications in a neonatal\n                    unit","author":"J M Lloreda-Garc\u00eda","year":"2016"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1177\/11297298211046755","article-title":"Accuracy of chest radiography compared to ultrasound for positioning the\n                    umbilical venous catheter in neonates: A meta-analysis and systematic\n                    review","volume":"24","author":"J Cao","year":"2023","journal-title":"J Vasc Access"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"774705","DOI":"10.3389\/fped.2021.774705","article-title":"Umbilical venous catheter update: A narrative review \u0131ncluding ultrasound and\n                    training","volume":"9","author":"V D\u2019Andrea","year":"2022","journal-title":"Front Pediatr"}],"container-title":["Zeitschrift f\u00fcr Geburtshilfe und Neonatologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2295-5110.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T14:55:07Z","timestamp":1730818507000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2295-5110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,6]]},"references-count":16,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2024,10,4]]},"published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2295-5110","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0948-2393","1439-1651"],"issn-type":[{"type":"print","value":"0948-2393"},{"type":"electronic","value":"1439-1651"}],"subject":[],"published":{"date-parts":[[2024,5,6]]}}}