{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T19:34:13Z","timestamp":1784748853286,"version":"3.55.0"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"09","license":[{"start":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T00:00:00Z","timestamp":1719273600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>As of now, there exists no established therapy for ELP. Retinoids, which are standard in treating cutaneous LP, do not exhibit positive effects in ELP. While topical glucocorticosteroids often yield favorable responses in esophageal inflammation, some cases prove recalcitrant or refractory. In such instances, various immunosuppressive therapies have been attempted with variable success.<\/jats:p>\n                  <jats:p>This report details a severe case of ELP that showed resistance to prednisolone, acitretin, alitretinoin, adalimumab, tacrolimus, hydroxychloroquine plus mycophenolate mofetil, and cyclophosphamide. The initiation of the JAK inhibitor tofacitinib induced an impressive clinical, endoscopic, and histological remission. This positive response to a JAK inhibitor is discussed in the context of our evolving understanding of the immune-mediated pathogenesis of this disease.<\/jats:p>","DOI":"10.1055\/a-2300-0375","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T18:50:08Z","timestamp":1719341408000},"page":"1384-1388","source":"Crossref","is-referenced-by-count":10,"title":["Remission of refractory esophageal lichen planus induced by tofacitinib"],"prefix":"10.1055","volume":"62","author":[{"given":"Valentina","family":"Bieneck","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6413-8816","authenticated-orcid":false,"given":"Annegrit","family":"Decker","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Gastroenterology, Hepatology, Endocrinology and Infectious Diseases, Medical Center, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5082-7979","authenticated-orcid":false,"given":"Annette","family":"Schmitt-Graeff","sequence":"additional","affiliation":[{"name":"University of Freiburg Faculty of Medicine, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6884-0135","authenticated-orcid":false,"given":"Wolfgang","family":"Kreisel","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Gastroenterology, Hepatology, Endocrinology and Infectious Diseases, Medical Center, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5147-0123","authenticated-orcid":false,"given":"Franziska","family":"Schauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,6,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1111\/odi.13323","article-title":"Worldwide prevalence of oral lichen planus: A systematic review and meta-analysis","volume":"27","author":"M\u00c1 Gonz\u00e1lez-Moles","year":"2021","journal-title":"Oral Dis"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1001\/jamadermatol.2019.3797","article-title":"Global Prevalence and Incidence Estimates of Oral Lichen Planus: A Systematic Review and Meta-analysis","volume":"156","author":"C Li","year":"2020","journal-title":"JAMA Dermatol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1056\/NEJMcp1103641","article-title":"Clinical practice. 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