{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T05:30:37Z","timestamp":1730871037961,"version":"3.28.0"},"reference-count":41,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Ursache der neurogenen Dysfunktion des unteren Harntraktes sind verschiedenste Sch\u00e4digungen des zentralen und peripheren Nervensystems. Daraus k\u00f6nnen diverse St\u00f6rungen von Harnspeicher- und Harnentleerungsfunktion der Blase entstehen, die sich in Symptomen wie Drangbeschwerden, Harninkontinenz, rezidivierenden Harnwegsinfekten und Blasenentleerungsst\u00f6rungen \u00e4u\u00dfern. Lebensqualit\u00e4tseinschr\u00e4nkungen, Gefahr f\u00fcr den oberen Harntrakt, Einschr\u00e4nkung der Erwerbsf\u00e4higkeit und Verschlechterung der Symptome der Grunderkrankung sind h\u00e4ufig die Folge. Ziel der Neuro-Urologie ist daher, neben dem Schutz des oberen Harntraktes, Kontinenz zu erhalten bzw. wiederherzustellen und die Lebensqualit\u00e4t der Betroffenen zu verbessern. Dazu stehen neben oraler Medikation und operativen Ma\u00dfnahmen auch medikament\u00f6se und elektrophysikalische intravesikale Therapieoptionen zur Verf\u00fcgung. Die \u00dcbersicht geht daher auf diese intravesikalen Therapieverfahren sowie deren Indikation und Stellenwert in der Neuro-Urologie ein.<\/jats:p>","DOI":"10.1055\/a-2307-4049","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T23:04:22Z","timestamp":1718838262000},"page":"344-350","source":"Crossref","is-referenced-by-count":0,"title":["Intravesikale Behandlungsoptionen in der Neuro-Urologie \u2013 eine \u00dcbersicht"],"prefix":"10.1055","volume":"55","author":[{"given":"Anke K.","family":"Jaekel","sequence":"additional","affiliation":[{"name":"Neuro-Urologie, Johanniter Neurologisches Rehabilitationszentrum Godeshoehe GmbH, Bonn, Germany"},{"name":"Klinik und Poliklinik f\u00fcr Urologie und Kinderurologie, Sektion Neuro-Urologie, Universita\u0308tsklinikum Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie C.","family":"Kn\u00fcpfer","sequence":"additional","affiliation":[{"name":"Neuro-Urologie, Johanniter Neurologisches Rehabilitationszentrum Godeshoehe GmbH, Bonn, Germany"},{"name":"Klinik und Poliklinik f\u00fcr Urologie und Kinderurologie, Sektion Neuro-Urologie, Universita\u0308tsklinikum Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Kirschner-Hermanns","sequence":"additional","affiliation":[{"name":"Neuro-Urologie, Johanniter Neurologisches Rehabilitationszentrum Godeshoehe GmbH, Bonn, Germany"},{"name":"Klinik und Poliklinik f\u00fcr Urologie und Kinderurologie, Sektion Neuro-Urologie, Universita\u0308tsklinikum Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/S1474-4422(15)00070-8","article-title":"Lower urinary tract dysfunction in the neurological patient: clinical assessment and management","volume":"14","author":"JN Panicker","year":"2015","journal-title":"Lancet Neurol"},{"volume-title":"Diagnostik und Therapie von neurogenen Blasenst\u00f6rungen","year":"2020","author":"C-A Haensch","key":"ref3"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1111\/bju.13976","article-title":"Intradetrusor onabotulinumtoxinA injections for refractory neurogenic detrusor overactivity incontinence: do we need urodynamic investigation for outcome assessment?","volume":"120","author":"M Koschorke","year":"2017","journal-title":"BJU Int"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1159\/000054774","article-title":"Renal failure in patients with neurogenic lower urinary tract dysfunction","volume":"20","author":"R Lawrenson","year":"2001","journal-title":"Neuroepidemiology"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1093\/qjmed\/hch105","article-title":"What drives quality of life in multiple sclerosis?","volume":"97","author":"L Hemmett","year":"2004","journal-title":"QJM"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1016\/j.euf.2021.08.007","article-title":"Efficacy and Safety of Surgical Treatments for Neurogenic Stress Urinary Incontinence in Adults: A Systematic Review","volume":"8","author":"S Musco","year":"2022","journal-title":"Eur Urol Focus"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1016\/s0022-5347(17)42717-0","article-title":"Effects of botulinum A toxin on detrusor-sphincter dyssynergia in spinal cord injury patients","volume":"139","author":"DD Dykstra","year":"1988","journal-title":"J Urol"},{"key":"ref12","first-page":"24","article-title":"Treatment of detrusor-sphincter dyssynergia with botulinum A toxin: a double-blind study","volume":"71","author":"DD Dykstra","year":"1990","journal-title":"Arch Phys Med Rehabil"},{"key":"ref13","first-page":"401","article-title":"Botulinum A-toxin in the treatment of detrusor hyperreflexia in spinal cord injured patients: A new alternative to medical and surgical procedures?","volume":"18","author":"M St\u00f6hrer","year":"1999","journal-title":"Neurourol Urodyn"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1097\/00005392-200009010-00018","article-title":"Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: a new alternative to anticholinergic drugs? 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