{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T05:26:57Z","timestamp":1730870817288,"version":"3.28.0"},"reference-count":6,"publisher":"Georg Thieme Verlag KG","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to develop an algorithm for pediatricians to use for infants diagnosed with fetal echogenic bowel (FEB) to ensure that each patient is fully evaluated for possible complications while avoiding unnecessary morbidity and mortality and health care-associated costs.<\/jats:p><jats:p>\n            Study Design\u2003This was a prospective cohort of neonates for which a diagnosis of FEB was made during a Level 2 anatomy ultrasound between February 2016 and January 2017. Women diagnosed with FEB were offered perinatal genetic counseling and testing. These women also received increased third trimester fetal surveillance, including daily fetal kick counts, fetal growth scans every 3 to 4 weeks beginning at 28 weeks, and weekly fetal nonstress test (NST) and\/or BPP beginning at 32 weeks. After delivery, neonates received a postnatal evaluation including birth weight, gestational age at birth, presence of other abnormalities, and associated perinatal morbidity and mortality. Comparison between findings was performed using chi-square test. All statistical evaluation was performed using SPSS.<\/jats:p><jats:p>\n            Results\u2003Among 919 pregnant patients who received Level 2 anatomy ultrasounds at a Regional Perinatal Center during the study period, 70 received a diagnosis of FEB. Of those diagnosed with FEB, 52 (74.3%) delivered at the same Regional Medical Center. Of these 52 delivered infants, 3 (5.8%) were intrauterine fetal demises (IUFDs) and 4 (7.6%) had unaffected twins. Only one multifetal gestation had the diagnosis of FEB in both the twins. Only 19 of the infants delivered had a kidney, ureter, and bladder X-ray (KUB) performed secondary to prematurity or abnormal exams.<\/jats:p><jats:p>\n            Conclusion\u2003This study showed that the majority of infants diagnosed with FEB had a normal exam following delivery, and that most of the neonatal outcomes of neonatal intensive care unit admissions and other neonatal complications are a result of prematurity rather than FEB. Although the algorithm did not have significant results, it is easy to follow and implement in larger studies.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2308-2151","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T22:59:37Z","timestamp":1713394777000},"page":"2278-2283","source":"Crossref","is-referenced-by-count":0,"title":["Defining an Evaluation Protocol for the Infant with Fetal Echogenic Bowel"],"prefix":"10.1055","volume":"41","author":[{"given":"Kendall","family":"Alsup","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University, Augusta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica L.","family":"Pearson","sequence":"additional","affiliation":[{"name":"The Wellness Collective, Sioux Falls, South Dakota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Bowe","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Spartanburg Regional Healthcare System, Spartanburg, South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Padmashree C.","family":"Woodham","sequence":"additional","affiliation":[{"name":"Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Medical College of Georgia at Augusta University, Augusta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,5,16]]},"reference":[{"issue":"8994","key":"ref1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0140-6736(96)90210-X","article-title":"Prognostic implications of fetal echogenic bowel","volume":"347","author":"R N Slotnick","year":"1996","journal-title":"Lancet"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"F256","DOI":"10.1136\/archdischild-2012-302017","article-title":"Outcome of infants presenting with echogenic bowel in the second trimester of pregnancy","volume":"98","author":"H D Buiter","year":"2013","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.3109\/14767050903551442","article-title":"Outcomes for fetal echogenic bowel during the second trimester ultrasound","volume":"23","author":"J I Iruretagoyena","year":"2010","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/ajmg.a.20168","article-title":"Hyperechogenic fetal bowel: a large French collaborative study of 682 cases","volume":"121A","author":"B Simon-Bouy","year":"2003","journal-title":"Am J Med Genet A"},{"issue":"08","key":"ref5","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/pd.3898","article-title":"Perinatal outcomes of fetal echogenic bowel","volume":"32","author":"E Saha","year":"2012","journal-title":"Prenat Diagn"},{"issue":"06","key":"ref6","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1097\/AOG.0b013e31821aa739","article-title":"Echogenic bowel on second-trimester ultrasonography: evaluating the risk of adverse pregnancy outcome","volume":"117","author":"K R Goetzinger","year":"2011","journal-title":"Obstet Gynecol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2308-2151.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T13:26:47Z","timestamp":1730813207000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2308-2151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,17]]},"references-count":6,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2024,11,4]]},"published-print":{"date-parts":[[2024,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2308-2151","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"type":"print","value":"0735-1631"},{"type":"electronic","value":"1098-8785"}],"subject":[],"published-other":{"date-parts":[[2024,4,17]]},"published":{"date-parts":[[2024,4,17]]}}}