{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:40:45Z","timestamp":1792190445395,"version":"4.4.0"},"reference-count":530,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Bronchiektasen-Erkrankung ist eine \u00e4tiologisch heterogene, chronische und oftmals progredient verlaufende Atemwegs- und Lungenerkrankung, die durch eine irreversible Erweiterung der Bronchien gekennzeichnet ist. Sie geht h\u00e4ufig mit einer erheblichen Symptomlast, multiplen Komplikationen sowie einer eingeschr\u00e4nkten Lebensqualit\u00e4t einher. Seit mehreren Jahren ist weltweit eine deutliche Zunahme der Pr\u00e4valenz der Bronchiektasen-Erkrankung mit einer relevanten \u00f6konomischen Belastung der Gesundheitssysteme zu beobachten. Die vorliegende konsensusbasierte Leitlinie ist die erste deutschsprachige Leitlinie, die das Management der Bronchiektasen-Erkrankung bei Erwachsenen behandelt. Die Leitlinie betont die Wichtigkeit der thorakalen Bildgebung mittels CT zur Diagnose und Differenzierung der Bronchiektasen sowie die Bedeutung der \u00c4tiologie zur Festlegung der Therapieans\u00e4tze. Es werden sowohl nicht-medikament\u00f6se als auch medikament\u00f6se Therapien ausf\u00fchrlich er\u00f6rtert. Zu den nicht-medikament\u00f6sen Ma\u00dfnahmen geh\u00f6ren Raucherentw\u00f6hnung, Physiotherapie, k\u00f6rperliches Training, Rehabilitation, nichtinvasive Beatmung, Thoraxchirurgie und Lungentransplantation. Bei den medikament\u00f6sen Therapien wird besonders auf die langfristige Anwendung von Mukolytika, Bronchodilatatoren, antiinflammatorischen Medikamenten und Antibiotika eingegangen. Dar\u00fcber hinaus geht die Leitlinie auf die Herausforderungen und Strategien bei der Behandlung einer oberen Atemwegsbeteiligung, von Komorbidit\u00e4ten und Exazerbationen sowie die sozialmedizinischen Aspekte und das Schwerbehindertenrecht ein. Zudem wird die Bedeutung der Patientenaufkl\u00e4rung und des Selbstmanagements hervorgehoben. Abschlie\u00dfend werden spezielle Lebensphasen wie Transition, Kinderwunsch, Schwangerschaft und Elternschaft sowie Palliativmedizin behandelt. Die Leitlinie zielt darauf ab, eine umfassende, konsensusbasierte und patientenzentrierte Versorgung zu gew\u00e4hrleisten, wobei individuelle Risiken und Bed\u00fcrfnisse ber\u00fccksichtigt werden.<\/jats:p>","DOI":"10.1055\/a-2311-9450","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T23:41:02Z","timestamp":1731109262000},"page":"833-899","source":"Crossref","is-referenced-by-count":4,"title":["Management erwachsener Patientinnen und Patienten mit Bronchiektasen-Erkrankung"],"prefix":"10.1055","volume":"78","author":[{"given":"Felix C.","family":"Ringshausen","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pneumologie und Infektiologie, Medizinische Hochschule Hannover (MHH), Hannover, Deutschland"},{"name":"Biomedical Research in End-Stage and Obstructive Lung Disease (BREATH), Deutsches Zentrum f\u00fcr Lungenforschung (DZL), Hannover, Deutschland"},{"name":"European Reference Network on Rare and Complex Respiratory Diseases (ERN-LUNG), Frankfurt, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Baumann","sequence":"additional","affiliation":[{"name":"Hals-, Nasen- und Ohrenklinik, Universit\u00e4tsklinikum Heidelberg, Heidelberg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"de Roux","sequence":"additional","affiliation":[{"name":"Pneumologische Praxis am Schloss Charlottenburg, Berlin, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Dettmer","sequence":"additional","affiliation":[{"name":"Biomedical Research in End-Stage and Obstructive Lung Disease (BREATH), Deutsches Zentrum f\u00fcr Lungenforschung (DZL), Hannover, Deutschland"},{"name":"Institut f\u00fcr Diagnostische und Interventionelle Radiologie, Medizinische Hochschule Hannover (MHH), Hannover, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Diel","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Epidemiologie, Universit\u00e4tsklinikum Schleswig-Holstein (UKSH), Kiel, Deutschland; LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Deutsches Zentrum f\u00fcr Lungenforschung (DZL), Grosshansdorf, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Eichinger","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Diagnostische und Interventionelle Radiologie, Thoraxklinik am Universit\u00e4tsklinikum Heidelberg, Heidelberg, Deutschland; Translational Lung Research Center Heidelberg (TLRC), Deutsches Zentrum f\u00fcr Lungenforschung (DZL), Heidelberg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Ewig","sequence":"additional","affiliation":[{"name":"Thoraxzentrum Ruhrgebiet, Kliniken f\u00fcr Pneumologie und Infektiologie, EVK Herne und Augusta-Kranken-Anstalt Bochum, Bochum, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Flick","sequence":"additional","affiliation":[{"name":"Klinische Abteilung f\u00fcr Pulmonologie, Universit\u00e4tsklinik f\u00fcr Innere Medizin, LKH-Univ. 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