{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:01:59Z","timestamp":1759449719688,"version":"build-2065373602"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Disorders of blood coagulation can lead to manifest spontaneous bleeding and an increased risk of bleeding during surgical procedures and interventions. Pathophysiologically, a distinction can be made between defects in primary haemostasis, which lead to impaired platelet adhesion and platelet aggregation, and disorders of secondary (plasmatic) haemostasis, which are characterised by impaired fibrin formation or fibrin stabilisation. Aetiologically, a distinction can be made between rare genetically-determined hereditary defects and common acquired coagulation disorders, which may be based on different pathomechanisms. This overview is intended to provide ophthalmic surgeons with a basis for the perioperative management of patients with genetically determined coagulation disorders undergoing ophthalmic surgery. As there are no specific recommendations in this regard, the recommendations are based on the procedure for other surgical interventions, taking into account the\n          specific bleeding risk associated with ophthalmic surgery.<\/jats:p>","DOI":"10.1055\/a-2315-2206","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T18:30:30Z","timestamp":1723746630000},"page":"944-951","source":"Crossref","is-referenced-by-count":0,"title":["Perioperative Management of Coagulation Disorders in Ophthalmic Surgery"],"prefix":"10.1055","volume":"241","author":[{"given":"Christoph","family":"Sucker","sequence":"additional","affiliation":[{"name":"Gerinnungszentrum, COAGUMED, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Zeitz","sequence":"additional","affiliation":[{"name":"Campus Benjamin Franklin, Charit\u00e9 Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Feltgen","sequence":"additional","affiliation":[{"name":"Augenklinik, Universit\u00e4tsspital Basel, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,8,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00347-018-0732-y","article-title":"Umgang mit gerinnungshemmenden Substanzen in der Ophthalmochirurgie \u2013 eine Umfrage unter Ophthalmochirurgen in Deutschland","volume":"115","author":"N Feltgen","year":"2018","journal-title":"Ophthalmologe"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s00347-018-0724-y","article-title":"Orale Antikoagulation: Aktuelle \u00dcbersicht und perioperatives Management in der Ophthalmochirurgie","volume":"116","author":"C Sucker","year":"2019","journal-title":"Ophthalmologe"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s00347-021-01438-w","article-title":"Antikoagulation und Thrombozytenfunktionshemmung: Was in der augen\u00e4rztlichen Praxis zu beachten ist","volume":"118","author":"O Zeitz","year":"2021","journal-title":"Ophthalmologe"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1016\/j.oret.2021.04.013","article-title":"Risk Factors for Severe Bleeding Complications in Vitreoretinal Surgery and the Role of Antiplatelet or Anticoagulant Agents","volume":"5","author":"P Lauermann","year":"2021","journal-title":"Ophthalmol Retina"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.2147\/OPTH.S361867","article-title":"Risk Factors for Severe Bleeding Complications in Glaucoma Surgery and the Role of Antiplatelet or Anticoagulant Agents","volume":"16","author":"P Lauermann","year":"2022","journal-title":"Clin Ophthalmol"},{"key":"ref6","doi-asserted-by":"crossref","DOI":"10.1515\/9783110418422-004","volume-title":"Grundlagen der Blutgerinnung","author":"C Sucker","year":"2017"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1161\/01.ATV.0000193624.28251.83","article-title":"What does it take to make the perfect clot?","volume":"26","author":"D M Monroe","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.5482\/HAMO-13-01-0003","article-title":"My patient is thrombocytopenic! Is (s)he? Why? And what shall I do? A practical approach to thrombocytopenia","volume":"33","author":"L Alberio","year":"2013","journal-title":"Hamostaseologie"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1080\/09537104.2019.1637835","article-title":"How I approach new onset thrombocytopenia","volume":"31","author":"F Swain","year":"2020","journal-title":"Platelets"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.3390\/ijms25042163","article-title":"Current Understanding of Immune Thrombocytopenia: A Review of Pathogenesis and Treatment Options","volume":"25","author":"A Mititelu","year":"2024","journal-title":"Int J Mol Sci"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"100784","DOI":"10.1016\/j.blre.2020.100784","article-title":"Inherited thrombocytopenias: an updated guide for clinicians","volume":"48","author":"A Pecci","year":"2021","journal-title":"Blood Rev"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1055\/s-0037-1617178","article-title":"Erworbene Pl\u00e4ttchenfunktionsst\u00f6rungen: Pathogenese, Klassifikation, H\u00e4ufigkeit, Diagnostik und Behandlung","volume":"28","author":"R E Scharf","year":"2008","journal-title":"Hamostaseologie"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/17474086.2019.1562333","article-title":"Platelet function assays in diagnosis: an update","volume":"12","author":"P Gresele","year":"2019","journal-title":"Expert Rev Hematol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1182\/blood-2017-05-782029","article-title":"Advances in the diagnosis and treatment of Von Willebrand disease","volume":"130","author":"R Sharma","year":"2017","journal-title":"Blood"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.hoc.2021.07.004","article-title":"Von Willebrand Disease: Current Status of Diagnosis and Management","volume":"35","author":"A C Weyand","year":"2021","journal-title":"Hematol Oncol Clin North Am"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.thromres.2020.07.051","article-title":"How I treat von Willebrand disease","volume":"196","author":"G Castaman","year":"2020","journal-title":"Thromb Res"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1159\/000214858","article-title":"Causes, etiology and diagnosis of acquired von Willebrand disease: a prospective diagnostic workup to establish the most effective therapeutic strategies","volume":"121","author":"C Sucker","year":"2009","journal-title":"Acta Haematol"},{"key":"ref19","doi-asserted-by":"crossref","DOI":"10.1515\/9783110418422-006","volume-title":"Angeborene und erworbene Gerinnungsdefekte","author":"C Sucker","year":"2017"}],"container-title":["Klinische Monatsbl\u00e4tter f\u00fcr Augenheilkunde"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2315-2206.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T23:24:19Z","timestamp":1759361059000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2315-2206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":18,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2024,8,15]]},"published-print":{"date-parts":[[2024,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2315-2206","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0023-2165","1439-3999"],"issn-type":[{"type":"print","value":"0023-2165"},{"type":"electronic","value":"1439-3999"}],"subject":[],"published":{"date-parts":[[2024,8]]}}}