{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T03:41:24Z","timestamp":1775706084629,"version":"3.50.1"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T00:00:00Z","timestamp":1714348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Carcinoma cuniculatum is a variant of squamous cell carcinoma, characterized by a slow growth with progressive crypt-like invasion of deep tissue. This tumor is frequently misdiagnosed as a benign skin lesion both clinically and histopathologically. The final diagnosis is often delayed as it requires a large sample biopsy. We report the case of a 67-year-old patient who presented to us with a recurring chronic ulcer over a surgical scar of 5 years of evolution.<\/jats:p><jats:p>Only after a wide resection of the chronic ulcer was it possible to achieve the correct diagnosis of this large and poorly evolving carcinoma. The subsequent reconstruction with a musculocutaneous gracilis free flap allowed the patient to walk again.<\/jats:p>","DOI":"10.1055\/a-2316-3824","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T23:13:15Z","timestamp":1714432395000},"page":"575-580","source":"Crossref","is-referenced-by-count":2,"title":["Consider Carcinoma Cuniculatum in Recurrent Foot Ulcer: A Case Report and Literature Review"],"prefix":"10.1055","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3273-1342","authenticated-orcid":false,"given":"Francisco","family":"Nunes-Abreu","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8754-4951","authenticated-orcid":false,"given":"Ruben","family":"Hidalgo-Caro","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Lorda-Barraguer","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8621-8136","authenticated-orcid":false,"given":"Victor","family":"Crist\u00f3bal-Redondo","sequence":"additional","affiliation":[{"name":"Department of Anatomopathology, Hospital General Universitario Dr. Balmis, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6127-908X","authenticated-orcid":false,"given":"F. Javier","family":"C\u00e9spedes-Guirao","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,6,10]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1365-2559.1981.tb01803.x","article-title":"Carcinoma (epithelioma) cuniculatum: a clinico-pathological study of nineteen cases and review of the literature","volume":"5","author":"P H McKee","year":"1981","journal-title":"Histopathology"},{"issue":"11","key":"ref2","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1097\/DAD.0000000000001457","article-title":"Carcinoma cuniculatum of the lower leg: a case report and proposed diagnostic criteria","volume":"41","author":"M Kunc","year":"2019","journal-title":"Am J 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Sakakibara","year":"2015","journal-title":"Eplasty"},{"issue":"03","key":"ref13","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/DAD.0000000000000117","article-title":"Verrucous carcinoma of the foot diagnosed using p53 and Ki-67 immunostaining in a patient with diabetic neuropathy","volume":"37","author":"Y Nakamura","year":"2015","journal-title":"Am J Dermatopathol"},{"issue":"04","key":"ref14","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00256-008-0622-5","article-title":"Verrucous carcinoma of the foot and enhancement assessment by MRI","volume":"38","author":"P L Wasserman","year":"2009","journal-title":"Skeletal Radiol"},{"issue":"01","key":"ref15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.4103\/0019-5154.174144","article-title":"Carcinoma cuniculatum: usefulness of radiological assessment","volume":"61","author":"N di Meo","year":"2016","journal-title":"Indian J 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