{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T14:09:06Z","timestamp":1781186946680,"version":"3.54.1"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Endocrinol Diabetes"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose In this study, the changes in microvascular circulation caused by\n                    pregestational and gestational diabetes were observed, without focusing on\n                    retinal findings, to reveal the effect of diabetes regulation.<\/jats:p><jats:p>\n          Methods A total of 135 subjects were included: 30 with gestational\n                    diabetes (GDM), 30 pregestational diabetes (PGDM), 30 healthy pregnant\n                    normoglycemic subjects, and 45 healthy non-pregnant subjects. All subjects were\n                    examined by optical coherence tomography (OCT) and angiography. The retina,\n                    retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), choroidal thickness\n                    (CT), superficial capillary plexus (SCP), deep capillary plexus (DCP),\n                    choriocapillaris (CC), vascular density (VD), and foveal avascular zone (FAZ)\n                    areas were measured.<\/jats:p><jats:p>\n          Results The foveal VD of SCP and DCP was significantly lower in the PGDM\n                    and GDM groups compared to the control groups (p:0.006 and p:0.001,\n                    respectively). CC VD was significantly higher in all pregnant groups compared to\n                    non-pregnant controls (p&lt;0.001). The choroidal thickness values were highest\n                    in the healthy pregnant group and lowest in the PGDM group. There was no\n                    significant difference in FAZ area, retina, RNFL and GCL thickness between the\n                    groups. In the PGDM group, a negative correlation was observed between the FAZ\n                    area and the HbA1c level (r:\u2212\u20090.417, p:0.043).<\/jats:p><jats:p>\n          Conclusion There was a decrease in vascular density in pregnant women with\n                    diabetes compared to healthy pregnant women and controls. In the pregnant group\n                    with PGDM, a narrowing of the FAZ area was observed with increasing worsening of\n                    diabetes control. Diabetes type and glycemic control could influence the\n                    microvascular changes even in the absence of clinical or retinal findings.<\/jats:p>","DOI":"10.1055\/a-2316-3903","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T22:52:30Z","timestamp":1717714350000},"page":"522-530","source":"Crossref","is-referenced-by-count":7,"title":["Optical Coherence Tomography Angiography Evaluation of\n                    Retinochoroidal Microvascular Circulation Differences in Pregnant Women with\n                    Pregestational and Gestational Diabetes Mellitus"],"prefix":"10.1055","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2544-6618","authenticated-orcid":false,"given":"\u00c7isil Erkan","family":"Pota","sequence":"additional","affiliation":[{"name":"The Department of Ophthalmology, Manavgat State Hospital, Antalya,\n                    Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet E","family":"Do\u011fan","sequence":"additional","affiliation":[{"name":"The Department of Ophthalmology, Akdeniz University Faculty of\n                    Medicine, Antalya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6773-4573","authenticated-orcid":false,"given":"G\u00fcl Alkan","family":"B\u00fclb\u00fcl","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology, Division of Perinatology,\n                    Akdeniz University Faculty of Medicine, Antalya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0007-5769","authenticated-orcid":false,"given":"Cem Y","family":"Sanhal","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology, Division of Perinatology,\n                    Akdeniz University Faculty of Medicine, Antalya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Pota","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology, Antalya Ministry of Health\n                    Kepez State Hospital, Antalya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1097\/AOG.0000000000002501","article-title":"ACOG Practice Bulletin No. 190: Gestational Diabetes Mellitus","volume":"131","author":"Committee on Practice B-O","year":"2018","journal-title":"Obstet Gynecol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1256S","DOI":"10.1093\/ajcn\/71.5.1256s","article-title":"Carbohydrate and lipid metabolism in pregnancy: Normal compared with gestational\n                    diabetes mellitus","volume":"71","author":"N F Butte","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"676","DOI":"10.2337\/dc09-1848","article-title":"International association of diabetes and pregnancy study groups recommendations\n                    on the diagnosis and classification of hyperglycemia in pregnancy","volume":"33","author":"International Association of Diabetes and Pregnancy Study\n                            Groups Consensus Panel","year":"2010","journal-title":"Diabetes Care"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"S13","DOI":"10.2337\/dc18-S002","article-title":"2. 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