{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T19:20:10Z","timestamp":1770232810691,"version":"3.49.0"},"reference-count":46,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n            Background and study aims This review aimed to provide an updated\n      and comprehensive review of capsule retention within diverticula, shedding light on the\n      characteristics and management of this rare event in capsule endoscopy.<\/jats:p><jats:p>\n            Methods A systematic literature search was conducted across\n      multiple databases. All observational studies that reported capsule retention in a\n      diverticulum among complication and outcomes, as well as case reports and series, were\n      included. Manual cross-checking of references was also performed. Two extractors performed\n      abstract and full-text reviews, as well as data-extraction.<\/jats:p><jats:p>\n            Results We found 167 references from Pubmed, Embase, and Web Of\n      Science. Sixty-five duplicates were removed and another 71 references were excluded.\n      Crosschecking of references found additional two articles. In total, 32 articles were\n      included, resulting in a total of 34 cases of retained capsules in diverticula. The median age\n      was 69 and the majority of the patients were male (76.5%). The most common retention occurred\n      in Meckel\u2019s diverticulum (32.4%) followed by Zenker\u2019s diverticulum (20.6%). Investigation of\n      capsule retention was done with x-ray (50%) and computed tomography (CT) scan (44.1%).\n      Seventeen cases (50%) were asymptomatic. Resolution of the retention happened with endoscopy\n      (35.3%) and surgical management (32.4%), as well as self-resolution (20.6%).<\/jats:p><jats:p>\n            Conclusions Due to the small number of cases, diverticula are not\n      a risk factor for incomplete capsule endoscopy examination. It affects mainly elderly, male,\n      asymptomatic patients, and typically is diagnosed with x-rays and CT scans. The most common\n      type is Meckel\u2019s diverticulum, and endoscopy is the primary management. Capsule endoscopy\n      retentions are extremely rare, with only 34 cases reported since the technology's\n      introduction.<\/jats:p>","DOI":"10.1055\/a-2320-7104","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T23:09:32Z","timestamp":1715036972000},"page":"E788-E796","source":"Crossref","is-referenced-by-count":4,"title":["Retention of endoscopic capsules in diverticula: Literature review of a capsule endoscopy rarity"],"prefix":"10.1055","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8980-8599","authenticated-orcid":false,"given":"Camilla","family":"Thorndal","sequence":"additional","affiliation":[{"name":"Surgical Research Unit, Odense University Hospital, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ola","family":"Selnes","sequence":"additional","affiliation":[{"name":"Surgical Research Unit, Odense University Hospital, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian Io","family":"Lei","sequence":"additional","affiliation":[{"name":"University Hospital of Coventry and Warwickshire, Coventry, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Schostek","sequence":"additional","affiliation":[{"name":"Ovesco Endoscopy AG, Tubingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2248-489X","authenticated-orcid":false,"given":"Anastasios","family":"Koulaouzidis","sequence":"additional","affiliation":[{"name":"Surgical Research Unit, Odense University Hospital, Odense, Denmark"},{"name":"Department of Clinical Research, University of Southern Denmark, Odense, Denmark"},{"name":"Department of Medicine, Odense University Hospital, Svendborg, Denmark"},{"name":"Department of Social Medicine and Public Health, Pomeranian Medical University, Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1177\/2050640616675219","article-title":"Capsule retention related to small bowel capsule endoscopy: a large European single-center 10-year clinical experience","volume":"5","author":"A Nemeth","year":"2017","journal-title":"United European Gastroenterol J"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1186\/s12876-020-01491-w","article-title":"Adverse events of video capsule endoscopy over the past two decades: a systematic review and proportion meta-analysis","volume":"20","author":"YC Wang","year":"2020","journal-title":"BMC Gastroenterol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3390\/diagnostics12051105","article-title":"Indications, detection, completion and retention rates of capsule endoscopy in two\n          decades of use: A systematic review and meta-analysis","volume":"12","author":"P Cortegoso Valdivia","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"518718","DOI":"10.1155\/2012\/518718","article-title":"Capsule retentions and incomplete capsule endoscopy examinations: an analysis of 2300 examinations","volume":"2012","author":"CM Hoog","year":"2012","journal-title":"Gastroenterol Res Pract"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1055\/a-0576-0566","article-title":"Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Technical Review","volume":"50","author":"E Rondonotti","year":"2018","journal-title":"Endoscopy"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"3726","DOI":"10.3748\/wjg.v19.i24.3726","article-title":"Small-bowel capsule endoscopy: a ten-point contemporary review","volume":"19","author":"A Koulaouzidis","year":"2013","journal-title":"World J Gastroenterol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1159\/000364821","article-title":"Successful retrieval of a retained capsule endoscope with single incision laparoscopic surgery","volume":"8","author":"Y Tashiro","year":"2014","journal-title":"Case Rep Gastroenterol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"198","DOI":"10.21037\/atm.2017.03.15","article-title":"Capsule retention: prevention, diagnosis and management","volume":"5","author":"E Rondonotti","year":"2017","journal-title":"Ann Transl Med"},{"key":"ref9","first-page":"383","article-title":"Small-bowel diverticulosis: perceptions and reality","volume":"184","author":"R Akhrass","year":"1997","journal-title":"J Am Coll Surg"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"549853","DOI":"10.1155\/2009\/549853","article-title":"Small-bowel diverticulosis:imaging findings and review of three cases","volume":"2009","author":"B De Peuter","year":"2009","journal-title":"Gastroenterol Res Pract"},{"key":"ref11","first-page":"9","article-title":"Epidemiology of diverticular disease -- systematic review of the literature","volume":"110","author":"I T\u0103nase","year":"2015","journal-title":"Chirurgia (Bucur)"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/00004836-200309000-00016","article-title":"Video Capsule entrapped in a Meckel's diverticulum","volume":"37","author":"Y Gortzak","year":"2003","journal-title":"J Clin Gastroenterol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1097\/01.mcg.0000152750.02645.b1","article-title":"Zenker's diverticulum: a contraindication for wireless capsule endoscopy?","volume":"39","author":"RM Ford","year":"2005","journal-title":"J Clin Gastroenterol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1111\/j.1442-2050.2005.00509.x","article-title":"Endoscopic retrieval of a capsule endoscope from a Zenker's diverticulum","volume":"18","author":"DT Simmons","year":"2005","journal-title":"Dis Esophagus"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"PA34","DOI":"10.1016\/s1542-3565(04)00552-x","article-title":"Endoscopic retrieval of a small bowel enteroscopy capsule lodged in a Zenker's diverticulum","volume":"3","author":"AB Knapp","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.2214\/AJR.04.1297","article-title":"Endoscopic video capsules: radiologic findings of spontaneous entrapment in small intestinal diverticula","volume":"185","author":"RC Gaba","year":"2005","journal-title":"AJR Am J Roentgenol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1016\/j.gie.2005.11.020","article-title":"M2A video capsule lodged in the Meckel's diverticulum","volume":"63","author":"WK Yu","year":"2006","journal-title":"Gastrointest Endosc"},{"key":"ref18","first-page":"19","article-title":"An analysis of failure and safety profiles of capsule endoscopy. [Chinese]","volume":"47","author":"W Wei","year":"2008","journal-title":"Zhonghua nei ke za zhi [Chinese journal of internal medicine]"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"E247","DOI":"10.1055\/s-2008-1077563","article-title":"Capsule endoscopy with retention of the capsule in a duodenal diverticulum","volume":"40","author":"P Ordubadi","year":"2008","journal-title":"Endoscopy"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.gie.2008.03.1085","article-title":"Capsule retention in a patient with small-bowel diverticulosis","volume":"69","author":"SA Giday","year":"2009","journal-title":"Gastrointest Endosc"},{"issue":"S 02","key":"ref21","doi-asserted-by":"crossref","first-page":"E199","DOI":"10.1055\/s-0030-1255696","article-title":"Capsule endoscopic detection of bleeding Meckel's diverticulum, with capsule retention in the diverticulum","volume":"42","author":"Y Tanaka","year":"2010","journal-title":"Endoscopy"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1159\/000329882","article-title":"Video capsule retention in a Zenker diverticulum","volume":"5","author":"A Horiuchi","year":"2011","journal-title":"Case Rep Gastroenterol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.14309\/00000434-201110002-00246","article-title":"Double-balloon enteroscopy for retrieval of retained small-bowel video capsules \u2013\n          A single center experience","volume":"2","author":"N Sonpal","year":"2011","journal-title":"Am J Gastroenterol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"E387","DOI":"10.1055\/s-0030-1256931","article-title":"Capsule retention in a Zenker's diverticulum","volume":"43","author":"A Ziachehabi","year":"2011","journal-title":"Endoscopy"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"E308","DOI":"10.1055\/s-0030-1256641","article-title":"Capsule retention in a giant Meckel's diverticulum containing multiple enteroliths","volume":"43","author":"N Courcoutsakis","year":"2011","journal-title":"Endoscopy"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"S529","DOI":"10.14309\/00000434-201210001-01333","article-title":"A case of video capsule retention in a rare epiphrenic diverticulum","volume":"107","author":"P Ekanayake","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"ref27","first-page":"A243","article-title":"Small bowel capsule endoscopy: A review of 232 studies undertaken at a single centre","volume":"2","author":"AM Verma","year":"2012","journal-title":"Gut"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1080\/08998280.2013.11928979","article-title":"Capsule endoscopy device retention and magnetic resonance imaging","volume":"26","author":"BW Anderson","year":"2013","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"ref29","first-page":"272","article-title":"Inadvertent and asymptomatic retention of an endoscopic capsule in a Zencker diverticulum","volume":"37","author":"FMA Garcia","year":"2014","journal-title":"Gastroenterologia Y Hepatologia"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4166\/kjg.2016.67.4.207","article-title":"Capsule endoscopy with retention of the capsule in a duodenal diverticulum: A case report","volume":"67","author":"S Kim","year":"2016","journal-title":"Korean J Gastroenterol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1111\/den.12795","article-title":"Capsule retention for 7.5 years in Meckel's diverticulum","volume":"29","author":"CR Ling","year":"2017","journal-title":"Dig Endosc"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"791","DOI":"10.12998\/wjcc.v6.i14.791","article-title":"Meckel's diverticulum diagnosis by video capsule endoscopy: A case report and review of literature","volume":"6","author":"D Garcia-Compean","year":"2018","journal-title":"World Journal of Clinical Cases"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"E33","DOI":"10.1177\/000313481808400117","article-title":"Retained capsule endoscopy in a patient with a Meckel diverticulum previously treated by endovascular embolization","volume":"84","author":"O Cano-Valderrama","year":"2018","journal-title":"American Surgeon"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1080\/00365521.2018.1553353","article-title":"Capsule endoscopy as a diagnostic test for Meckel's diverticulum","volume":"54","author":"L Lin","year":"2019","journal-title":"Scand J Gastroenterol"},{"key":"ref35","first-page":"134","article-title":"Randomised controlled trial of early capsule endoscopy versus colonoscopy following negative gastroscopy in acute gastro-intestinal bleeding","volume":"7","author":"S Ostrowski","year":"2019","journal-title":"United Europ Gastroenterol J"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"e72","DOI":"10.1097\/MPG.0000000000002723","article-title":"Retention of a wireless endoscopic capsule in the Meckel diverticulum of a 12-year-old boy","volume":"71","author":"B Kang","year":"2020","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"S898","DOI":"10.14309\/01.ajg.0000709008.13648.2b","article-title":"S1740 Lost in space: Video capsule out of orbit causing a colo-vaginal fistula","volume":"115","author":"SM D'Souza","year":"2020","journal-title":"Am J Gastroenterol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"36","DOI":"10.18528\/ijgii200023","article-title":"A rare complication of capsule endoscopy, retained in diverticula: A report of two cases","volume":"10","author":"MK Saad","year":"2021","journal-title":"Int J Gastrointest Intervention"},{"key":"ref39","first-page":"740","article-title":"Capsule endoscopy retention in Zenker's diverticulum","volume":"114","author":"M Rey","year":"2022","journal-title":"Revista Espanola De Enfermedades Digestivas"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"e00797","DOI":"10.14309\/crj.0000000000000797","article-title":"Capsule retention in Meckel's diverticulum during evaluation for iron deficiency anemia","volume":"9","author":"MG Noujaim","year":"2022","journal-title":"ACG Case Rep J"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.rgmxen.2022.05.013","article-title":"Is intestinal diverticulosis a risk factor in video capsule endoscopy?","volume":"87","author":"MM D\u00edaz-Alc\u00e1zar","year":"2022","journal-title":"Rev Gastroenterol Mex (Engl Ed)"},{"key":"ref42","first-page":"188","article-title":"A rare case of video capsule retention","volume":"37","author":"A Cheah","year":"2022","journal-title":"J Gastroenterol Hepatol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1055\/s-2003-41596","article-title":"Capsule endoscopy in a patient with Zenker's diverticulum","volume":"35","author":"L Aabakken","year":"2003","journal-title":"Endoscopy"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1016\/j.gie.2016.12.024","article-title":"Retention associated with video capsule endoscopy: systematic review and meta-analysis","volume":"85","author":"M Rezapour","year":"2017","journal-title":"Gastrointest Endosc"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1055\/s-0034-1391855","article-title":"Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline","volume":"47","author":"M Pennazio","year":"2015","journal-title":"Endoscopy"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1111\/j.1440-1746.2011.06618.x","article-title":"Education and imaging: gastrointestinal: videocapsule retention: rationale for surgical indication","volume":"26","author":"A Biondi","year":"2011","journal-title":"J Gastroenterol Hepatol"}],"container-title":["Endoscopy International 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