{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T19:20:48Z","timestamp":1771615248844,"version":"3.50.1"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n               Background Glaucoma is a leading cause of blindness worldwide. We evaluated the efficacy, confounders, and safety of the Preserflo Microshunt over a one-year follow-up period.<\/jats:p><jats:p>\n               Methods In this retrospective monocentric study, 111 eyes were evaluated. 83 eyes had primary open angle glaucoma, and 28 eyes secondary open angle glaucoma. Intraocular pressure (IOP), visual acuity, number of glaucoma medications, complications, and reoperations were evaluated postoperatively, at 1, 3, 6, 9, and 12 months. The influence of age, sex, type of glaucoma, previous surgery and lens status was also analysed. Bleb revision was indicated if corrected IOP exceeded 18\u2009mmHg.<\/jats:p><jats:p>\n               Results Intraocular pressure significantly decreased from 24.50\u2009\u00b1\u20098.94 to 14.62\u2009\u00b1\u20094.86\u2009mmHg (4\u200a\u2013\u200a32\u2009mmHg; p\u2009&lt;\u20090.001), the number of medications from 3.19\u2009\u00b1\u20091.14 to 0.98\u2009\u00b1\u20091.39 (0\u200a\u2013\u200a4; p\u2009&lt;\u20090.001). Confounders of interest did not affect efficacy. Bleb revision was performed in 22.5% of eyes and a cyclophotocoagulation was performed in 9.9% of eyes. Complete surgical success (IOP \u2264\u200917\u2009mmHg, IOP reduction \u2265\u200920%, without medication) was achieved in 36.9% (n\u2009=\u200941) and qualified success (with medication) in 51.4% (n\u2009=\u200957) of eyes. Transient hypotension (\u2264\u20095\u2009mmHg) occurred in 19.8% after primary implantation and in 1.8% after bleb revision (duration \u2264\u20093 months).<\/jats:p><jats:p>\n               Conclusion To date, the Preserflo Microshunt has demonstrated good efficacy and a low risk profile.<\/jats:p>","DOI":"10.1055\/a-2325-9286","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T18:56:25Z","timestamp":1721847385000},"page":"1048-1056","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy, Confounders and Safety of the Preserflo Microshunt"],"prefix":"10.1055","volume":"241","author":[{"given":"Cemre","family":"Altas","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Augenheilkunde, Universit\u00e4tsmedizin Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Fuchsluger","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Augenheilkunde, Universit\u00e4tsmedizin Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Brockmann","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Augenheilkunde, Universit\u00e4tsmedizin Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Graum\u00fcller","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenheilkunde, Universit\u00e4tsmedizin Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Walckling","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Augenheilkunde, Universit\u00e4tsmedizin Rostock, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,7,24]]},"reference":[{"key":"ref1","volume-title":"Augenheilkunde","author":"G K Lang","year":"2019","edition":"6. \u00fcberarbeitet"},{"key":"ref2","first-page":"e11686","volume-title":"Epidemiology of Glaucoma: The Past, Present, and Predictions for the Future","author":"K Allison"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1136\/bjophthalmol-2016-EGSguideline.002","article-title":"European Glaucoma Society Terminology and Guidelines for Glaucoma, 4th Edition \u2013 Chapter 2: Classification and Terminology Supported by the EGS Foundation: Part 1: Foreword; Introduction; Glossary; Chapter 2 Classification and Terminology","volume":"101","year":"2017","journal-title":"Br J Ophthalmol"},{"key":"ref4","volume-title":"Glaukom in der Praxis; ein Leitfaden. 2., v\u00f6llig neubearbeitete Aufl","author":"W Leydhecker","year":"1973"},{"key":"ref5","first-page":"377","volume-title":"Kapitel 13: Glaukom","author":"J J Kanski","year":"2008","edition":"6. 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