{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T18:10:17Z","timestamp":1730916617879,"version":"3.28.0"},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2024,7]]},"abstract":"\n Anamnese und klinischer Befund\u2002Wir berichten \u00fcber eine 34-j\u00e4hrige Patientin sowie einen 50-j\u00e4hrigen Patienten, die beide mit einem schweren septischen Krankheitsbild in unsere Notaufnahme transportiert wurden.<\/jats:p>\n Untersuchungen\u2002Beide Patienten mussten im Verlauf reanimiert werden und zeigten klinisch sowie laborchemisch Zeichen einer schweren bakteriellen Infektion.<\/jats:p>\n Diagnose\u2002Bei beiden Patienten lag eine invasive Infektion mit Gruppe-A-Streptokokken vor. Bei der weiblichen Patientin fand sich eine Streptokokkensepsis mit schwerer Pneumonie, bei dem m\u00e4nnlichen Patienten bestand eine durch Streptokokken hervorgerufene nekrotisierende Fasziitis der oberen Extremit\u00e4t.<\/jats:p>\n Therapie und Verlauf\u2002W\u00e4hrend die Patientin trotz s\u00e4mtlicher intensivmedizinischer Ma\u00dfnahmen noch im Schockraum der Notaufnahme verstarb, \u00fcberlebte der Patient nach rascher chirurgischer Therapie und l\u00e4ngerem Intensivaufenthalt.<\/jats:p>\n Folgerung\u2002Der Zustand von Patienten mit invasiven Infektionen durch Gruppe-A-Streptokokken kann sich rasch klinisch verschlechtern. Eine umgehende Diagnosestellung und die Einleitung meist interdisziplin\u00e4rer Therapiema\u00dfnahmen sind wichtig. Dennoch k\u00f6nnen diese Erkrankungen t\u00f6dlich verlaufen.<\/jats:p>","DOI":"10.1055\/a-2327-4789","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T04:48:16Z","timestamp":1718167696000},"page":"771-774","source":"Crossref","is-referenced-by-count":0,"title":["Invasive Streptokokken-Infektionen \u2013 eine interdisziplin\u00e4re Herausforderung"],"prefix":"10.1055","volume":"149","author":[{"given":"Markus","family":"W\u00f6rnle","sequence":"additional","affiliation":[{"name":"Zentrale Notaufnahme Klinikum Innenstadt, LMU Klinikum, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/j.mcna.2013.03.003","article-title":"Serious group a streptococcal infections","volume":"97","author":"C J Wong","year":"2013","journal-title":"Med Clin North Am"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1055\/s-2008-1055433","article-title":"Diagnose und Therapie der nekrotisierenden Fasziitis","volume":"120","author":"P Kujath","year":"1995","journal-title":"Dtsch Med Wochenschr"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1001\/jama.241.8.803","article-title":"Necrotizing fasciitis","volume":"241","author":"J R Fisher","year":"1979","journal-title":"JAMA"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1056\/NEJM199702133360715","article-title":"Invasive group A streptococcal infections","volume":"336","author":"P Kujath","year":"1997","journal-title":"N Engl J Med"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1093\/infdis\/166.1.31","article-title":"Aspects of pathogenesis of serious group A streptococcal infections in Sweden, 1988-1989","volume":"166","author":"S E Holm","year":"1992","journal-title":"J Infect Dis"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/0002-9610(77)90283-5","article-title":"Bacteriology of necrotizing fasciitis","volume":"134","author":"A Guiliano","year":"1977","journal-title":"Am J Surg"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1097\/00000658-198711000-00018","article-title":"Improved results from a standardized approach in treating patients with necrotizing fasciitis","volume":"206","author":"L A Sudarsky","year":"1987","journal-title":"Ann Surg"},{"first-page":"146","volume-title":"Investigations upon the nature, causes and treatment of hospital gangrene as it prevailed in the confederate armies 1861-1865","author":"J Jones","key":"ref8"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/BF02862686","article-title":"Zur Kenntnis und Behandlung des nekrotisierenden Erysipels","volume":"144","author":"W Pfanner","year":"1918","journal-title":"Dtsch Zeitschr Chir"},{"key":"ref10","first-page":"416","article-title":"Necrotizing fasciitis","volume":"18","author":"B Wilson","year":"1952","journal-title":"Am Surgeon"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"595","DOI":"10.3238\/arztebl.m2023.0164","article-title":"Locally increased incidence of periorbital necrotizing fasciitis \u2013 a case series","author":"A Schuh","year":"2023","journal-title":"Dtsch Arztebl Int"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"114","DOI":"10.3238\/arztebl.m2023.0261","article-title":"The Increase in invasive bacterial infections with respiratory transmission in Germany, 2022\/2023","volume":"121","author":"R Singer","year":"2024","journal-title":"Dtsch Arztebl Int"}],"container-title":["DMW - Deutsche Medizinische Wochenschrift"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2327-4789.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T14:42:49Z","timestamp":1730817769000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2327-4789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,11]]},"references-count":12,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2024,6,11]]},"published-print":{"date-parts":[[2024,7]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2327-4789","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0012-0472","1439-4413"],"issn-type":[{"type":"print","value":"0012-0472"},{"type":"electronic","value":"1439-4413"}],"subject":[],"published":{"date-parts":[[2024,6,11]]}}}