{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T06:08:19Z","timestamp":1786946899680,"version":"build-2736575974"},"reference-count":42,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr Surg"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Anastomotic stricture (AS) is the second most common complication after esophageal atresia (EA) repair. We aimed to evaluate the data in the Turkish Esophageal Atresia Registry to determine the risk factors for AS development after EA repair in a large national cohort of patients.<\/jats:p><jats:p>\n          Methods\u2003The data between 2015 and 2021 were evaluated. Patients were enrolled into two groups according to the occurrence of AS. Patients with AS (AS group) and without AS (non-AS group) were compared according to demographic and operative features, postoperative intubation status, and postoperative complications, such as anastomotic leaks, fistula recanalization, and the presence of gastroesophageal reflux (GER). A multivariable logistic regression analysis was performed to define the risk factors for the development of AS after EA repair.<\/jats:p><jats:p>\n          Results\u2003Among the 713 cases, 144 patients (20.19%) were enrolled into the AS group and 569 (79.81%) in the non-AS group. The multivariable logistic regression showed that, being a term baby (odds ratio [OR]: 1.706; p\u2009=\u20090.006), having a birth weight over 2,500\u2009g (OR: 1.72; p\u2009=\u20090.006), presence of GER (OR: 5.267; p\u2009&lt;\u20090.001), or having a recurrent tracheoesophageal fistula (TEF, OR: 4.363; p\u2009=\u20090.006) were the risk factors for the development of AS.<\/jats:p><jats:p>\n          Conclusions\u2003The results of our national registry demonstrate that 20% of EA patients developed AS within their first year of life. In patients with early primary anastomosis, birth weight greater than 2,500\u2009g and presence of GER were risk factors for developing AS. When patients with delayed anastomosis were included, in addition to the previous risk factors, being a term baby, and having recurrent TEF also became risk factors.<\/jats:p><jats:p>\n          Level of Evidence\u2003III.<\/jats:p>","DOI":"10.1055\/a-2340-9078","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T23:04:12Z","timestamp":1717801452000},"page":"550-557","source":"Crossref","is-referenced-by-count":10,"title":["Determining the Risk Factors for Anastomotic Stricture Development after Esophageal Atresia Repair: Results from the Turkish Esophageal Atresia Registry"],"prefix":"10.1055","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5408-2772","authenticated-orcid":false,"given":"Can \u0130hsan","family":"\u00d6ztorun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c7i\u011fdem","family":"Ulukaya Durakba\u015fa","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Istanbul Medeniyet University, \u0130stanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1505-6042","authenticated-orcid":false,"given":"Tutku","family":"Soyer","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Co\u015fkun","family":"\u00d6zcan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Ege University, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binali","family":"F\u0131r\u0131nc\u0131","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berat Dilek","family":"Demirel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130lhan","family":"\u00c7ift\u00e7i","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Sel\u00e7uk University, Konya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe","family":"Parlak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Uluda\u011f University, Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3696-4090","authenticated-orcid":false,"given":"Mustafa Onur","family":"\u00d6ztan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Izmir Katip Celebi University, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclnur","family":"G\u00f6ll\u00fc Bahad\u0131r","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Ankara University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130brahim","family":"Akkoyun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Konya Education and Research Hospital, Konya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe","family":"Karaman","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, University of Health Sciences Turkey, Ankara Dr Sami Ulus Children's Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cengiz","family":"G\u00fcl","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, University of Health Sciences Turkey, Zeynep Kamil Maternity and Children Health and Research Application Center, \u0130stanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcl","family":"\u015ealc\u0131","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fcseyin","family":"\u0130lhan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 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Sel\u00e7uk","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Cukurova University, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcrsu","family":"K\u0131yan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Maramara University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Onur","family":"Erdem","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Adnan Menderes University, Ayd\u0131n, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9031-0373","authenticated-orcid":false,"given":"Osman","family":"Uzunlu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Pamukkale University, Denizli, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Sisli Hamidiye Etfal Education and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"\u00d6z\u00e7ak\u0131r","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazile","family":"Ert\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Kocaman University, Mu\u011fla, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ba\u015fak","family":"Erginel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Istanbul University, 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