{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:26Z","timestamp":1787004866278,"version":"build-2736575974"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Gegenstand und Ziel Ziel dieser retrospektiven Studie ist die Beschreibung\n                    der Intoxikation mit tremorgenen Mykotoxinen nach Walnussaufnahme bei einer\n                    gro\u00dfen Hundepopulation und die Evaluierung der Entwicklung der klinischen\n                    Symptomatik unter der initiierten Therapie.<\/jats:p>\n                  <jats:p>Material und Methoden Vierundf\u00fcnfzig Hunde wurden in die Studie\n                    eingeschlossen, die vornehmlich mit Tremor, Hyper\u00e4sthesie, Hyperthermie und\n                    Ataxie innerhalb weniger Stunden nach beobachteter oraler Aufnahme von Waln\u00fcssen\n                    oder begr\u00fcndetem Verdacht vorstellig wurden.<\/jats:p>\n                  <jats:p>Ergebnisse Vornehmlich wurden die Patienten im Winter und Fr\u00fchling\n                    vorstellig. Dreiundf\u00fcnfzig der 54 Hunde wurden zur symptomatischen sowie\n                    dekontaminierenden und eliminierenden Therapie station\u00e4r aufgenommen (98%). Zur\n                    symptomatischen Therapie kamen bei 14 Hunden eine antikonvulsive Therapie (26%)\n                    sowie bei der H\u00e4lfte der Patienten eine antiemetische Therapie (n=27; 50%) zum\n                    Einsatz. Eine forcierte Emesis zur Dekontamination wurde aufgrund des\n                    Schweregrads der neurologischen Symptome lediglich bei 6 Patienten eingeleitet\n                    (11%). Als weitere dekontaminierende Ma\u00dfnahme erfolgte eine orale Gabe von\n                    Aktivkohle nach Besserung der klinischen Symptome (n=39; 72%). Die Mehrzahl der\n                    Hunde (n=45; 83%) erhielt eine intraven\u00f6se Lipidtherapie zur Elimination sowie\n                    isotone kristalloide Infusionsl\u00f6sung zum Ausgleich von Fl\u00fcssigkeitsverlusten.\n                    Nebenwirkungen nach intraven\u00f6ser Lipidtherapie wurden nicht beobachtet. Der\n                    Gro\u00dfteil der Patienten verblieb 2 Tage station\u00e4r (n=44; 81%). Bei der Mehrzahl\n                    der Patienten war die klinische Untersuchung am Tag der Entlassung unauff\u00e4llig\n                    (n=39; 72%). Potenzielle Folgesch\u00e4den nach Mykotoxinvergiftung wurden bei keinem\n                    der Patienten im weiteren Verlauf dokumentiert.<\/jats:p>\n                  <jats:p>Schlussfolgerung Aufgrund der Lipophilie von Mykotoxinen kann der Einsatz\n                    einer intraven\u00f6sen Lipidtherapie zur Toxinelimination in Erw\u00e4gung gezogen\n                    werden. Die Prognose bei Mykotoxinvergiftung nach Walnussaufnahme nach\n                    dekontaminierenden und eliminierenden Ma\u00dfnahmen ist gut.<\/jats:p>\n                  <jats:p>Klinische Relevanz Bei unspezifischen neurologischen Symptomen wie Tremor,\n                    Ataxie und Hyper\u00e4sthesie sowie entsprechendem Vorbericht sollte eine\n                    Intoxikation mit Mykotoxin behafteten Waln\u00fcssen in Betracht gezogen werden.<\/jats:p>","DOI":"10.1055\/a-2344-6146","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T18:49:07Z","timestamp":1724352547000},"page":"211-219","source":"Crossref","is-referenced-by-count":2,"title":["Mykotoxinvergiftung nach Walnussaufnahme bei 54\n                    Hunden"],"prefix":"10.1055","volume":"52","author":[{"given":"Vanessa","family":"Braun","sequence":"additional","affiliation":[{"name":"Abteilung Innere Medizin, Kleintierklinik Ettlingen, Tier\u00e4rztliche\n                    Klinik fu\u0308r Chirurgie, Praxis fu\u0308r Kleintiere, Ettlingen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Kanstinger","sequence":"additional","affiliation":[{"name":"Abteilung Innere Medizin, Kleintierklinik Ettlingen, Tier\u00e4rztliche\n                    Klinik fu\u0308r Chirurgie, Praxis fu\u0308r Kleintiere, Ettlingen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothee","family":"Dahlem","sequence":"additional","affiliation":[{"name":"Abteilung Innere Medizin, Kleintierklinik Ettlingen, Tier\u00e4rztliche\n                    Klinik fu\u0308r Chirurgie, Praxis fu\u0308r Kleintiere, Ettlingen"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1080\/00480169.2008.36823","article-title":"Presumptive tremorgenic mycotoxicosis in a dog in New Zealand, after eating\n            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Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2344-6146.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T11:05:54Z","timestamp":1730804754000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2344-6146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":33,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2024,8,22]]},"published-print":{"date-parts":[[2024,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2344-6146","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8]]}}}