{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:54:40Z","timestamp":1778500480684,"version":"3.51.4"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Metab Res"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of our study is to explore the relationship between remnant cholesterol\n                    (RC) levels and visceral adipose tissue (VAT) in the US adult population. This\n                    cross-sectional study utilized data from 5301 participants aged 20 to 59 years\n                    gathered by the National Health and Nutrition Examination Survey (NHANES). RC\n                    was determined by deducting both high-density lipoprotein cholesterol (HDL-c)\n                    and low-density lipoprotein cholesterol (LDL-c) from total cholesterol (TC), and\n                    VAT was measured using dual-energy X-ray absorptiometry. Visceral obesity is\n                    defined as a VAT area \u2265\u2009100 cm2. With increasing quartiles of RC\n                    levels, the prevalence of visceral obesity rises (16.51% vs. 36.11% vs. 55.66%\n                    vs. 74.48%, p&lt;0.001). After adjusting for confounders, RC levels positively\n                    correlate with visceral obesity risk (OR=1.039, 95% CI 1.031\u20131.048, p&lt;0.001).\n                    Additionally, individuals with low LDL-c\/high RC and those with high LDL-c\/low\n                    RC showed 2.908-fold (95% CI 1.995\u20134.241) and 1.310-fold (95% CI 1.022\u20131.680)\n                    higher risk of visceral obesity, respectively, compared to those with low\n                    LDL-c\/low RC. Receiver Operating Characteristic (ROC) and Decision Curve\n                    Analysis (DCA) show RC\u2019s superior predictive ability over other lipid markers.\n                    Subgroup analysis showed that the relationship between RC and visceral obesity\n                    was more ronounced in those with cardiovascular disease. Smooth curve fitting\n                    indicated a nonlinear relationship between RC levels and VAT area. Our study\n                    highlights that elevated levels of RC are associated with adverse accumulation\n                    of VAT. However, the causal relationship between RC and visceral obesity\n                    requires additional investigation.<\/jats:p>","DOI":"10.1055\/a-2357-2579","type":"journal-article","created":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T22:47:36Z","timestamp":1722034056000},"page":"47-54","source":"Crossref","is-referenced-by-count":4,"title":["The Relationship Between Remnant Cholesterol and Visceral Adipose\n                    Tissue: A National Cross-Sectional Study"],"prefix":"10.1055","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6577-0565","authenticated-orcid":false,"given":"Zhaoxiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Endocrinology, Affiliated Kunshan Hospital of Jiangsu University,\n                    Kunshan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao","family":"Zhong","sequence":"additional","affiliation":[{"name":"Clinical Nutrition, Affiliated Kunshan Hospital of Jiangsu University,\n                    Kunshan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menghuan","family":"Wu","sequence":"additional","affiliation":[{"name":"Endocrinology, Shanghai Putuo District Liqun Hospital, Shanghai,\n                    China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuejing","family":"Shao","sequence":"additional","affiliation":[{"name":"Endocrinology, Affiliated Wujin Hospital of Jiangsu University,\n                    Changzhou, China"},{"name":"Endocrinology, Wujin Clinical College of Xuzhou Medical University,\n                    Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Gu","sequence":"additional","affiliation":[{"name":"Endocrinology, Affiliated Wujin Hospital of Jiangsu University,\n                    Changzhou, China"},{"name":"Endocrinology, Wujin Clinical College of Xuzhou Medical University,\n                    Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengjiao","family":"Xu","sequence":"additional","affiliation":[{"name":"Endocrinology, Affiliated Wujin Hospital of Jiangsu University,\n                    Changzhou, China"},{"name":"Endocrinology, Wujin Clinical College of Xuzhou Medical University,\n                    Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qichao","family":"Yang","sequence":"additional","affiliation":[{"name":"Endocrinology, Affiliated Wujin Hospital of Jiangsu University,\n                    Changzhou, China"},{"name":"Endocrinology, Wujin Clinical College of Xuzhou Medical University,\n                    Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,7,26]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.semcancer.2023.03.008","article-title":"Excess body weight: Novel 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Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2357-2579.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T23:31:55Z","timestamp":1736551915000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2357-2579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,26]]},"references-count":34,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2025,1,10]]},"published-print":{"date-parts":[[2025,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2357-2579","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0018-5043","1439-4286"],"issn-type":[{"value":"0018-5043","type":"print"},{"value":"1439-4286","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,26]]}}}