{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:34:16Z","timestamp":1777422856933,"version":"3.51.4"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n               Objective\u2003Dizziness is one of the most prevalent and debilitating symptoms associated with vestibular schwannoma (VS), and there are little data on contributing or alleviating factors in the perioperative setting. In this study, we aimed to evaluate whether vestibular nerve sectioning or labyrinthectomy concomitant with surgical resection would improve dizziness in the postoperative period.<\/jats:p><jats:p>\n               Methods\u2003This is a retrospective study of a consecutive series of VS patients who underwent resection at a large tertiary care center between 2009 and 2023. Dizziness at 6 months was the primary endpoint, whereas facial nerve and hearing outcomes were secondary endpoints. Fisher's exact test was used to identify significant differences between categorical variables, and multivariate logistic regression analysis was performed to identify predictors of dizziness as well as facial nerve and hearing outcomes.<\/jats:p><jats:p>\n               Results\u2003A total of 333 patients underwent resection of VS at our institution. There was no significant difference in binary reported dizziness based on surgical approach (p\u2009=\u20090.14). However, patients reported significantly less dizziness at discharge (p\u2009&lt;\u20090.01) as well as 6-month (p\u2009=\u20090.02) and 1-year (p\u2009&lt;\u20090.01) follow-up in the translabyrinthine group. On the other hand, patients who underwent labyrinth-sparing approaches reported a significant increase in dizziness that remained up to 1 year from the time of surgery.<\/jats:p><jats:p>\n               Conclusion\u2003Our data suggest that labyrinthectomy may improve dizziness symptoms in patients with VS. Selective VN sectioning does not appear to affect dizziness or hearing outcomes. Finally, surgical approach does not affect facial nerve outcomes.<\/jats:p>","DOI":"10.1055\/a-2360-9474","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T23:32:54Z","timestamp":1720222374000},"page":"395-402","source":"Crossref","is-referenced-by-count":2,"title":["Labyrinthectomy Improves Dizziness in Patients with Vestibular Schwannoma"],"prefix":"10.1055","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1749-8143","authenticated-orcid":false,"given":"Jeffrey I.","family":"Traylor","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Venkatesh","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander S.","family":"Fabiano","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron R.","family":"Plitt","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States"},{"name":"Division of Neurological Surgery, Aurora St. Luke's Hospital, Milwaukee, Wisconsin, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankur","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Isaacson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The University of Texas Southwestern Medical Center, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce E.","family":"Mickey","sequence":"additional","affiliation":[{"name":"Division of Neurological Surgery, Aurora St. Luke's Hospital, Milwaukee, Wisconsin, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7292-1018","authenticated-orcid":false,"given":"Samuel L.","family":"Barnett","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,7,24]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"981","DOI":"10.3171\/2022.7.JNS221104","article-title":"Development and validation of a new disease-specific quality of life instrument for sporadic vestibular schwannoma: the Mayo Clinic Vestibular Schwannoma Quality of Life Index","volume":"138","author":"M L Carlson","year":"2022","journal-title":"J Neurosurg"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1097\/MAO.0b013e3181e8c7cb","article-title":"Audiovestibular factors influencing quality of life in patients with conservatively managed sporadic vestibular schwannoma","volume":"31","author":"S K Lloyd","year":"2010","journal-title":"Otol Neurotol"},{"issue":"01","key":"ref3","first-page":"67","article-title":"Untreated vestibular schwannoma: vertigo is a powerful predictor for health-related quality of life","volume":"59","author":"E Myrseth","year":"2006","journal-title":"Neurosurgery"},{"issue":"S 02","key":"ref4","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1017\/S0022215113003216","article-title":"Factors associated with symptom-specific psychological and functional impact among acoustic neuroma patients","volume":"128","author":"J E Brooker","year":"2014","journal-title":"J Laryngol Otol"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/00129492-200107000-00022","article-title":"Labyrinthectomy versus vestibular neurectomy: long-term physiologic and clinical outcomes","volume":"22","author":"D J Eisenman","year":"2001","journal-title":"Otol Neurotol"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1177\/019459988509300202","article-title":"Facial nerve grading system","volume":"93","author":"J W House","year":"1985","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"03","key":"ref7","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0194-5998(95)70101-X","article-title":"Committee on Hearing and Equilibrium guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma). 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