{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T10:11:36Z","timestamp":1776766296933,"version":"3.51.2"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n            Einleitung Die Prognose von Patienten im prolongierten Weaning ist insbesondere in Abh\u00e4ngigkeit vom Weaning-Outcome eingeschr\u00e4nkt. Daten zur gesundheitsbezogenen Lebensqualit\u00e4t nach prolongiertem Weaning im Langzeitverlauf existieren bis heute jedoch nur sp\u00e4rlich.\n    <\/jats:p><jats:p>\n            Methodik Es wurde die gesundheitsbezogene Lebensqualit\u00e4t nach prolongiertem Weaning mittels SRI-Fragebogen erfasst (SRI = Severe Respiratory Insufficiency Questionnaire).\n    <\/jats:p><jats:p>\n            Ergebnisse Insgesamt haben 39 von 83 Patienten mit prolongiertem Weaning den SRI-Fragebogen ausgef\u00fcllt. Der zeitliche Abstand zur Entlassung aus dem Weaning-Zentrum betrug im Median 3,5 Jahre (IQR 2,4\u20134,5 Jahre). In der Gesamtgruppe lag der Median des Summenscores bei 56,4 (IQR 38,8\u201373,5). Patienten mit invasiver au\u00dferklinischer Beatmung (N=15) hatten eine deutliche schlechtere Lebensqualit\u00e4t im Summenscore als Patienten mit erfolgreicher Entw\u00f6hnung ohne Fortsetzung der maschinellen Beatmung (N=13) und solchen mit Fortsetzung einer nicht-invasiven Beatmung (N=11); Kruskal-Wallis-Test: H (2, N=39) = 7,875446; P=0,0195. Statistisch signifikante Unterschiede im Sinne einer schlechteren Lebensqualit\u00e4t bei Patienten mit invasiver au\u00dferklinischer Beatmung zeigten sich insbesondere auf den Subdom\u00e4nen der sozialen Beziehungen (P=0,0325), der krankheitsbezogenen \u00c4ngste (P=0,0096) und des psychischen Befindens (P=0,0079).\n    <\/jats:p><jats:p>\n            Schlussfolgerung Patienten mit erfolglosem prolongierten Weaning und invasiver au\u00dferklinischer Langzeitbeatmung haben eine deutlich schlechtere gesundheitsbezogene Lebensqualit\u00e4t als Patienten mit erfolgreicher Entw\u00f6hnung vom Respirator. Weitere Studien mit h\u00f6heren Fallzahlen sind notwendig, um weitere Einflussgr\u00f6\u00dfen auf die gesundheitsbezogene Lebensqualit\u00e4t im prolongierten Weaning zu untersuchen.\n    <\/jats:p>","DOI":"10.1055\/a-2368-4865","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T22:48:25Z","timestamp":1722898105000},"page":"141-146","source":"Crossref","is-referenced-by-count":5,"title":["Lebensqualit\u00e4t im Langzeitverlauf nach prolongiertem Weaning in Abh\u00e4ngigkeit vom Weaning-Status"],"prefix":"10.1055","volume":"79","author":[{"given":"Bernd","family":"Sch\u00f6nhofer","sequence":"additional","affiliation":[{"name":"Innere Medizin, Pneumologie und Intensivmedizin, EvKB, Universit\u00e4tsklinikum Ostwestfalen Lippe (OWL) der Universit\u00e4t Bielefeld, Bielefeld, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Paul","sequence":"additional","affiliation":[{"name":"Pneumologie, Internistische Intensivmedizin und Schlafmedizin, KRH Klinikum Siloah, Hannover, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Suchi","sequence":"additional","affiliation":[{"name":"data-quest Suchi & Berg GmbH, G\u00f6ttingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6219-5013","authenticated-orcid":false,"given":"Maximilian","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Pneumologie, Kliniken der Stadt K\u00f6ln gGmbH, K\u00f6ln, Deutschland"},{"name":"Lehrstuhl f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah Bettina","family":"Stanzel","sequence":"additional","affiliation":[{"name":"Pneumologie, Kliniken der Stadt K\u00f6ln gGmbH, K\u00f6ln, Deutschland"},{"name":"Lehrstuhl f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram","family":"Windisch","sequence":"additional","affiliation":[{"name":"Pneumologie, Kliniken der Stadt K\u00f6ln gGmbH, K\u00f6ln, Deutschland"},{"name":"Lehrstuhl f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Berger","sequence":"additional","affiliation":[{"name":"Pneumologie, Kliniken der Stadt K\u00f6ln gGmbH, K\u00f6ln, Deutschland"},{"name":"Lehrstuhl f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,8,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1055\/a-0828-9710","article-title":"WeanNet: Das Netzwerk pneumologischer Weaningzentren","volume":"73","author":"B Sch\u00f6nhofer","year":"2019","journal-title":"Pneumologie"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1055\/a-1010-8764","article-title":"Prolongiertes Weaning \u2013 S2k-Leitlinie herausgegeben von der Deutschen Gesellschaft f\u00fcr Pneumologie und Beatmungsmedizin e.V","volume":"73","author":"B Sch\u00f6nhofer","year":"2019","journal-title":"Pneumologie"},{"key":"ref3","first-page":"197","article-title":"Prolonged Weaning from Mechanical Ventilation. 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