{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T23:06:42Z","timestamp":1779318402033,"version":"3.51.4"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Padiatr"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background Renal dysplasia (RD) is a major cause of chronic kidney disease (CKD) in\n          childhood. Herein, we present a single-center experience about distinctive features of\n          different subtypes of dysplasia.<\/jats:p>\n                  <jats:p>Methods All children with RD admitted between January 2018 and June 2019 were\n          included in this cross-sectional study. Patients were classified as having unilateral RD,\n          bilateral RD, posterior urethral valves (PUV), and multicystic-dysplastic kidneys\n          (MCDK).<\/jats:p>\n                  <jats:p>Results A total of 198 patients (108 unilateral RD, 31 bilateral RD, 16 PUV, and 43\n          MCDK) with a follow-up period of 80 (1.5\u2013240) months were included. The overall\n          consanguinity rate was 22%, whereas it was 56% in bilateral RD patients. Two-thirds had\n          additional urogenital anomalies. Hypertension was detected in 16% of the patients, and 20%\n          had median proteinuria of 16 (5.2\u2013173) mg\/m2\/h, which was significantly higher\n          in the PUV and bilateral RD groups. The overall rate of CKD was 23%, which was more\n          frequent in bilateral RD and PUV groups. The median age at end-stage renal disease was\n          91.5 (0.5\u2013208) months, including 12 renal transplant patients.<\/jats:p>\n                  <jats:p>Conclusions As different subtypes of RD have distinct clinical and prognostic\n          features, the follow-up of RD patients should be individualized, and modifiable\n          complications such as proteinuria and HT should be monitored closely.<\/jats:p>","DOI":"10.1055\/a-2373-0785","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T18:59:35Z","timestamp":1726858775000},"page":"156-163","source":"Crossref","is-referenced-by-count":1,"title":["Distinguishing Features of Childhood Renal Dysplasia"],"prefix":"10.1055","volume":"238","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7628-4722","authenticated-orcid":false,"given":"Ece","family":"Mekik","sequence":"additional","affiliation":[{"name":"Pediatric Nephrology, Ankara University School of Medicine, Ankara,\n          Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeynep Birsin","family":"\u00d6z\u00e7akar","sequence":"additional","affiliation":[{"name":"Pediatric Nephrology, Ankara University School of Medicine, Ankara,\n          Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilgun","family":"Cakar","sequence":"additional","affiliation":[{"name":"Pediatric Nephrology, Ankara University School of Medicine, Ankara,\n          Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burcu Biral","family":"Co\u015fkun","sequence":"additional","affiliation":[{"name":"Pediatric Nephrology, Ankara University School of Medicine, Ankara,\n          Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beyza","family":"Do\u011fanay","sequence":"additional","affiliation":[{"name":"Biostatistics, Ankara University School of Medicine, Ankara,\n          Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatos","family":"Yalcinkaya","sequence":"additional","affiliation":[{"name":"Pediatric Nephrology, Ankara University School of Medicine, Ankara,\n          Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,9,20]]},"reference":[{"key":"ref1","first-page":"1701","volume-title":"Epidemiology and Management of Chronic Kidney Disease in Children. 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