{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T23:13:01Z","timestamp":1759792381405,"version":"build-2065373602"},"reference-count":5,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>During embryogenesis, the vertebrae begin development during the 6th week of gestation via two lateral chondrification centers per segment. It was assumed that when disruptions occur in the process of somitogenesis during membranous vertebral body formation, chondrification and ossification will follow the anomalous membranous vertebral body scaffolding, resulting in an anomalous vertebral formation, such as a hemivertebra. Another hypothesis is that hemivertebra may result from anomalous distribution of intersegmental arteries of the vertebral column. There is no description in the medical literature of \u201cexcess linear calcifications\u201d of part of the fetal vertebra, characterized by the presence of linear calcifications in the vertebrae of a developing fetus. In the first two trimesters of pregnancy, the fetal vertebrae usually show three calcified points in an axial section: the vertebral body and two transverse processes. Premature linear vertebral calcification was defined as an anterior or posterior echogenic connection between two of the points (Fig. 1). In this study, we describe seven cases of premature fetal linear vertebral calcification.<\/jats:p>","DOI":"10.1055\/a-2375-0250","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T19:02:36Z","timestamp":1724353356000},"page":"505-507","source":"Crossref","is-referenced-by-count":0,"title":["Fetal premature excess vertebral linear calcification: a case series"],"prefix":"10.1055","volume":"46","author":[{"given":"Moshe","family":"Bronshtein","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel"},{"name":"Faculty of Social Welfare and Health Sciences, University of Haifa Faculty of Social Welfare and Health Sciences, Haifa, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayala","family":"Gover","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, Lady Davies Carmel Medical Center, Haifa, Israel"},{"name":"Ruth and Bruch Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Beloosesky","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel"},{"name":"Rappaprot Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6290-2945","authenticated-orcid":false,"given":"Gal","family":"Bachar","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nizar","family":"Khatib","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"publisher","first-page":"853","DOI":"10.7863\/jum.2004.23.6.853.","article-title":"\u201cPrenatal sonographic diagnosis of hemivertebra\u201d","volume":"23","author":"B Weisz","year":"2004","journal-title":"Journal of Ultrasound in Medicine"},{"issue":"04","key":"ref2","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1111\/cge.14188.","article-title":"\u201cGenetics of non-isolated hemivertebra: A systematic review of fetal, neonatal, and infant cases","volume":"102","author":"JE Powel","year":"2022","journal-title":"\u201d Clinical Genetics"},{"issue":"04","key":"ref3","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1359\/jbmr.2003.18.4.760.","article-title":"\u201cMicroarchitectural and physical changes during fetal growth in human vertebral bone","volume":"18","author":"S Nuzzo","year":"2003","journal-title":"\u201d Journal of Bone and Mineral Research"},{"issue":"04","key":"ref4","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1302\/0301-620x.68b4.3733836.","article-title":"\u201cHemivertebra as a cause of scoliosis: A study of 104 patients","volume":"68","author":"MJ McMaster","year":"1986","journal-title":"\u201d Journal of Bone and Joint Surgery \u2013 Series B"},{"issue":"02","key":"ref5","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1002\/ajmg.1320270220.","article-title":"\u201cGenetic aspects of early childhood scoliosis","volume":"27","author":"JM Connor","year":"1987","journal-title":"\u201d Am J Med Genet"}],"container-title":["Ultraschall in der Medizin - European Journal of Ultrasound"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2375-0250.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T22:32:55Z","timestamp":1759789975000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2375-0250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,22]]},"references-count":5,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2025,10,6]]},"published-print":{"date-parts":[[2025,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2375-0250","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0172-4614","1438-8782"],"issn-type":[{"type":"print","value":"0172-4614"},{"type":"electronic","value":"1438-8782"}],"subject":[],"published":{"date-parts":[[2024,8,22]]}}}