{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T18:23:39Z","timestamp":1792434219810,"version":"4.5.0"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009128","name":"Research for Patient Benefit Programme","doi-asserted-by":"crossref","award":["NIHR 201571"],"award-info":[{"award-number":["NIHR 201571"]}],"id":[{"id":"10.13039\/501100009128","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n            Background Post-endoscopy upper gastrointestinal cancer (PEUGIC) is an important key performance indicator for endoscopy quality. We examined variation in PEUGIC rates among endoscopy providers in England and explored associated factors.  \n            \n    <\/jats:p><jats:p>\n            Methods The was a population-based, retrospective, case\u2013control study, examining data from National Cancer Registration and Analysis Service and Hospital Episode Statistics databases for esophageal and gastric cancers diagnosed between 2009 and 2018 in England. PEUGIC were cancers diagnosed 6 to 36 months after an endoscopy that did not diagnose cancer. Associated factors were identified using multivariable logistic regression analyses.<\/jats:p><jats:p>\n            Results The national PEUGIC rate was 8.5%, varying from 5% to 13% among endoscopy providers. Factors associated with PEUGIC included: female sex (odds ratio [OR] 1.29 [95%CI 1.23\u20131.36]); younger age (age &gt;80 years, OR 0.52 [0.48\u20130.56], compared with \u226460 years); increasing comorbidity (Charlson score &gt;4, OR 5.06 [4.45\u20135.76]); history of esophageal ulcer (OR 3.30 [3.11\u20133.50]), Barrett\u2019s esophagus (OR 3.21 [3.02\u20133.42]), esophageal stricture (OR 1.28 [1.20\u20131.37]), or gastric ulcer (OR 1.55 [1.44\u20131.66]); squamous cell carcinoma (OR 1.50 [1.39\u20131.61]); and UK national endoscopy accreditation status \u2013 providers requiring improvement (OR 1.10 [1.01\u20131.20]), providers never assessed (OR 1.24 [1.04\u20131.47]).<\/jats:p><jats:p>\n            Conclusion PEUGIC rates varied threefold among endoscopy providers, suggesting unwarranted differences in endoscopy quality. PEUGIC was associated with endoscopy findings known to be associated with upper gastrointestinal cancer and a lack of national endoscopy provider accreditation. PEUGIC variations suggest an opportunity to raise performance standards to detect upper gastrointestinal cancers earlier and improve outcomes.<\/jats:p>","DOI":"10.1055\/a-2378-1464","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T23:19:55Z","timestamp":1724973595000},"page":"17-28","source":"Crossref","is-referenced-by-count":16,"title":["The variation in post-endoscopy upper gastrointestinal cancer rates among endoscopy providers in England and associated factors: a population-based study"],"prefix":"10.1055","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6531-9205","authenticated-orcid":false,"given":"Umair","family":"Kamran","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Sandwell and West Birmingham NHS Trust, Birmingham, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicity","family":"Evison","sequence":"additional","affiliation":[{"name":"Data Science, Research, Development and Innovation, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva Judith Ann","family":"Morris","sequence":"additional","affiliation":[{"name":"Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J","family":"Brookes","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The Royal Wolverhampton NHS Trust, Wolverhampton, United Kingdom of Great Britain and Northern Ireland"},{"name":"Faculty of Science and Engineering, Research Institute in Healthcare Science, University of Wolverhampton, Wolverhampton, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9507-0295","authenticated-orcid":false,"given":"Matthew David","family":"Rutter","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, United Kingdom of Great Britain and Northern Ireland"},{"name":"Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mimi","family":"McCord","sequence":"additional","affiliation":[{"name":"-, Heartburn Cancer UK, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola J","family":"Adderley","sequence":"additional","affiliation":[{"name":"Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Trudgill","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Sandwell and West Birmingham NHS Trust, Birmingham, United Kingdom of Great Britain and Northern Ireland"},{"name":"Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"ref4","doi-asserted-by":"publisher","first-page":"E46","DOI":"10.1055\/s-0034-1365524","article-title":"How commonly is upper gastrointestinal cancer missed at endoscopy? 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