{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T11:56:22Z","timestamp":1764244582364,"version":"3.46.0"},"reference-count":41,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A 7-year-old French Bulldog presented with an acanthomatous ameloblastoma\n                    affecting approximately 30% of the right mandibular body. We utilized a\n                    patient-specific 3D-printed surgical template to perform lateral fenestration of\n                    the mandible and elevation of the inferior alveolar nerve (IAN), facilitating\n                    nerve preservation during subsequent segmental mandibulectomy. The resulting\n                    critical-sized bone defect was anatomically stabilized using a patient-specific\n                    polyetheretherketone (PEEK) bridging plate. The recovery process was uneventful,\n                    with maintained occlusion and orofacial sensitivity.<\/jats:p>\n                  <jats:p>Similar to cases in humans with ameloblastoma, preserving orofacial sensitivity\n                    through the preservation of the inferior alveolar nerve seems feasible in dogs.\n                    Consequently, potential negative consequences of permanent regional denervation,\n                    which are unavoidable in traditional mandibulectomy, can be avoided. Bridging\n                    the ostectomy with a PEEK plate, offering advantages such as radiolucency,\n                    absence of imaging artifacts, and a modulus of elasticity similar to bone,\n                    proved to be functional in this canine patient, with no signs of complications\n                    observed up to the latest follow-up at 6 months.<\/jats:p>","DOI":"10.1055\/a-2401-4956","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T18:30:25Z","timestamp":1729794625000},"page":"300-307","source":"Crossref","is-referenced-by-count":0,"title":["Template based segmental mandibulectomy with nerve preservation and\n                    patient-specific PEEK plate reconstruction in a dog"],"prefix":"10.1055","volume":"52","author":[{"given":"Anne","family":"Zobel","sequence":"additional","affiliation":[{"name":"Small Animal Clinic, Surgery, Department of Veterinary Medicine, Free\n                    University of Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"B\u00f6ttcher","sequence":"additional","affiliation":[{"name":"Small Animal Clinic, Surgery, Department of Veterinary Medicine, Free\n                    University of Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"830258","DOI":"10.3389\/fvets.2022.830258","article-title":"Surgical Margins for Ameloblastoma in Dogs: A Review With an Emphasis on the\n                    Future","volume":"9","author":"S Goldschmidt","year":"2022","journal-title":"Front Vet Sci"},{"key":"ref2","first-page":"433","article-title":"The intramandibular course of the inferior alveolar nerve","volume":"108","author":"R B Carter","year":"1971","journal-title":"J Anat"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0278-2391(84)90318-5","article-title":"Ameloblastoma of the mandible treated by resection, preservation of the inferior\n                    alveolar nerve, and bone grafting","volume":"42","author":"W Tingchun","year":"1984","journal-title":"Oral Maxillofac Surg"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1055\/s-0038-1639348","article-title":"Refined Approach to Preservation of the Inferior Alveolar Nerve during Resection\n                    and Primary Reconstruction of the Mandible","volume":"12","author":"S Tereshchuk","year":"2019","journal-title":"Craniomaxillofac Trauma Reconstr"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1097\/00005537-200307000-00029","article-title":"Inferior Alveolar Nerve\u2013Preserving Mandibulectomy for Nonmalignant Lesions","volume":"113","author":"M A Kuriakose","year":"2003","journal-title":"Laryngoscope"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.archoralbio.2011.09.007","article-title":"A review of the mandibular and maxillary nerve supplies and their clinical\n                    relevance","volume":"57","author":"L F Rodella","year":"2012","journal-title":"Arch Oral Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.cvsm.2005.03.005","article-title":"Mandibulectomy and Maxillectomy","volume":"35","author":"FJ M Verstraete","year":"2005","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.5037\/jomr.2011.2101","article-title":"Injury of the Inferior Alveolar Nerve during Implant Placement: a Literature\n                    Review","volume":"2","author":"G Juodzbalys","year":"2011","journal-title":"J Oral Maxillofac Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1016\/j.jcms.2019.11.012","article-title":"Complications associated with orthognathic surgery: A retrospective study of 485\n                    cases","volume":"47","author":"F M Zaroni","year":"2019","journal-title":"J Craniomaxillofac Surg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.joms.2014.10.030","article-title":"Sensory Outcomes After Reconstruction of Lingual and Inferior Alveolar Nerve\n                    Discontinuities Using Processed Nerve Allograft\u2014A Case Series","volume":"73","author":"J R Zuniga","year":"2015","journal-title":"J Oral Maxillofac Surg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"117","DOI":"10.14639\/0392-100X-2408","article-title":"Use of a CAD-CAM inferior alveolar nerve salvage template during mandibular\n                    resection for benign lesions","volume":"39","author":"F Ricotta","year":"2019","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.jcms.2022.02.008","article-title":"Inferior alveolar nerve preservation during resection and reconstruction of the\n                    mandible for benign tumors as a factor improving patient\u2019s quality of life","volume":"50","author":"S Tereshchuk","year":"2022","journal-title":"J Craniomaxillofac Surg"},{"key":"ref13","first-page":"515","volume-title":"Mandibulectomy techniques. In: Oral and Maxillofacial Surgery in Dogs and\n                    Cats","author":"FJ M Verstraete","year":"2020"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"900031","DOI":"10.3389\/fvets.2022.900031","article-title":"A Retrospective Study on Mandibular Reconstruction Following Excision of Canine\n                    Acanthomatous Ameloblastoma","volume":"9","author":"A J Tsugawa","year":"2022","journal-title":"Front Vet Sci"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"637","DOI":"10.2460\/ajvr.80.7.637","article-title":"Kinematic analysis of mandibular motion before and after mandibulectomy and\n                    mandibular reconstruction in dogs","volume":"80","author":"B Arzi","year":"2019","journal-title":"Am J Vet Res"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1532-950X.2004.04019.x","article-title":"Mandibular Reconstruction of a Partial Hemimandibulectomy in a Dog with Severe\n                    Malocclusion","volume":"33","author":"R J Boudrieau","year":"2004","journal-title":"Vet Surg"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"566","DOI":"10.2460\/javma.251.5.566","article-title":"Clinical outcomes of patient-specific porous titanium endoprostheses in dogs\n                    with tumors of the mandible, radius, or tibia: 12 cases (2013\u20132016)","volume":"251","author":"J P Bray","year":"2017","journal-title":"J Am Vet Med Assoc"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1055\/s-0034-1371356","article-title":"Computer-Assisted Mandibular Reconstruction using a Patient-Specific\n                    Reconstruction Plate Fabricated with Computer-Aided Design and Manufacturing\n                    Techniques","volume":"7","author":"F Wilde","year":"2014","journal-title":"Craniomaxillofac Trauma Reconstr"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s12663-019-01323-9","article-title":"Patient-Specific Mandibular Reconstruction Plates Increase Accuracy and\n                    Long-Term Stability in Immediate Alloplastic Reconstruction of Segmental\n                    Mandibular Defects","volume":"19","author":"A N Zeller","year":"2020","journal-title":"J Maxillofac Oral Surg"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1148\/rg.246045065","article-title":"Artifacts in CT: Recognition and Avoidance","volume":"24","author":"J F Barrett","year":"2004","journal-title":"Radiographics"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1007\/s10143-020-01384-2","article-title":"Carbon fiber\u2013reinforced PEEK versus titanium implants: an in vitro comparison of\n                    susceptibility artifacts in CT and MR imaging","volume":"44","author":"T Kr\u00e4tzig","year":"2021","journal-title":"Neurosurg Rev"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.joms.2022.03.004","article-title":"Reduction of CT Artifacts Using Polyetheretherketone (PEEK),\n                    Polyetherketoneketone (PEKK), Polyphenylsulfone (PPSU), and Polyethylene (PE)\n                    Reconstruction Plates in Oral Oncology","volume":"80","author":"J Lommen","year":"2022","journal-title":"J Oral Maxillofac Surg"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"012045","DOI":"10.1088\/1757-899X\/1259\/1\/012045","article-title":"Study on Polyether-ether-ketone (PEEK) dental implant, future alternatives to\n                    Titanium","volume":"1259","author":"A Parekh","year":"2022","journal-title":"IOP Conf Ser Mater Sci Eng"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"57","DOI":"10.4103\/1735-3327.377577","article-title":"Evaluation of stress and deformation in bone with titanium, CFR-PEEK and\n                    zirconia ceramic implants by finite element analysis","volume":"20","author":"G Mahalakshmi","year":"2023","journal-title":"Dent Res J"},{"key":"ref25","first-page":"ZE10","article-title":"Polyetheretherketone (PEEK) in Dentistry","volume":"13","author":"V B Benakatti","year":"2019","journal-title":"J Clin Diagn Res"},{"key":"ref26","first-page":"137","article-title":"PEEK polymer in orthodontics: a scoping review","volume":"23","author":"M Paglia","year":"2022","journal-title":"Eur J Paediatr Dent"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jcms.2022.06.002","article-title":"Clinical application of 3D-printed PEEK implants for repairing mandibular\n                    defects","volume":"50","author":"Y Li","year":"2022","journal-title":"J Craniomaxillofac Surg"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2460\/javma.253.1.73","article-title":"Outcomes following surgical excision or surgical excision combined with\n                    adjunctive, hypofractionated radiotherapy in dogs with oral squamous cell\n                    carcinoma or fibrosarcoma","volume":"253","author":"J Riggs","year":"2018","journal-title":"J Am Vet Med Assoc"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/jsap.12624","article-title":"Outcome and prognostic factors following curative-intent surgery for oral\n                    tumours in dogs: 234 cases (2004 to 2014)","volume":"58","author":"B N Sarowitz","year":"2017","journal-title":"Journal of Small Animal Practice"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"615","DOI":"10.2460\/ajvr.1983.44.04.615","article-title":"Electrophysiologic studies of the cutaneous nerves of the head of the dog","volume":"44","author":"L R Whalen","year":"1983","journal-title":"Am J Vet Res"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41368-023-00230-7","article-title":"Promotion effect of TGF-\u03b2-Zfp423-ApoD pathway on lip sensory recovery after\n                    nerve sacrifice caused by nerve collateral compensation","volume":"15","author":"P Ma","year":"2023","journal-title":"Int J Oral Sci"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jcms.2022.06.002","article-title":"Clinical application of 3D-printed PEEK implants for repairing mandibular\n                    defects","volume":"50","author":"Y Li","year":"2022","journal-title":"J Craniomaxillofac Surg"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"e248826","DOI":"10.1136\/bcr-2022-248826","article-title":"Mandibular recontouring with polyetheretherketone (PEEK) patient-specific\n                    implants","volume":"15","author":"R Nocini","year":"2022","journal-title":"BMJ Case Rep"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s11282-011-0071-z","article-title":"Quantitative analysis of metallic artifacts caused by dental metals: comparison\n                    of cone-beam and multi-detector row CT scanners","volume":"27","author":"J Chindasombatjaroen","year":"2011","journal-title":"Oral Radiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.5433\/1679-0359.2017v38n4p1925","article-title":"Ex vivo biomechanical analysis of two methods of osteosynthesis in canine\n                    mandibular fractures","volume":"38","author":"LJ E Isaka","year":"2017","journal-title":"Semin Cienc Agrar"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"702","DOI":"10.2460\/ajvr.78.6.702","article-title":"Biomechanical evaluation of two plating configurations for fixation of a simple\n                    transverse caudal mandibular fracture model in cats","volume":"78","author":"C L Greiner","year":"2017","journal-title":"Am J Vet Res"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.3390\/jcm11123308","article-title":"Mechanical Fatigue Performance of Patient-Specific Polymer Plates in Oncologic\n                    Mandible Reconstruction","volume":"11","author":"J Lommen","year":"2022","journal-title":"J Clin Med"},{"key":"ref39","first-page":"2","article-title":"Regenerative Approach to Bilateral Rostral Mandibular Reconstruction in a Case\n                    Series of Dogs","volume":"4","author":"B Arzi","year":"2015","journal-title":"Front Vet Sci"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"299","DOI":"10.11607\/prd.1407","article-title":"Horizontal Ridge Augmentation with a Collagen Membrane and a Combination of\n                    Particulated Autogenous Bone and Anorganic Bovine Bone\u2013Derived Mineral: A\n                    Prospective Case Series in 25 Patients","volume":"33","author":"I A Urban","year":"2013","journal-title":"Int J Periodontics Restorative Dent"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1055\/s-00035023","article-title":"Comparison of two beta-tricalcium phosphate composite grafts used for\n                    reconstruction of mandibular critical size bone defects","volume":"22","author":"M C Nolff","year":"2009","journal-title":"Vet Comp Orthop Traumatol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jcms.2009.07.010","article-title":"Comparison of computed tomography and microradiography for graft evaluation\n                    after reconstruction of critical size bone defects using \u03b2-tricalcium\n                    phosphate","volume":"38","author":"M C Nolff","year":"2010","journal-title":"J Craniomaxillofac Surg"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2401-4956.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T11:54:41Z","timestamp":1764244481000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2401-4956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":41,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2024,10,24]]},"published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2401-4956","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"type":"print","value":"1434-1239"},{"type":"electronic","value":"2567-5842"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}