{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T20:12:44Z","timestamp":1767211964662,"version":"3.28.0"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"10","license":[{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n            Background and study aims To assess the diagnostic value of contrast-enhanced endoscopic ultrasound (CE-EUS) for autoimmune pancreatitis and other solid pancreatic masses.<\/jats:p><jats:p>\n            Patients and methods A systematic search of PubMed, Embase, and Web of Science was performed from inception to October 2022. We calculated individual and pooled sensitivities and specificities to determine the diagnostic ability of CE-EUS. In addition, we calculated I2 to test for heterogeneity and explored the source of heterogeneity by meta-regression analysis.<\/jats:p><jats:p>\n            Results A total of 472 patients from seven eligible studies were included. The mean sensitivity and specificity of the Bivariate analysis were 0.84 (95% CI 0.71\u20130.92) and 0.95 (95% CI 0.84\u20130.99), respectively. The diagnostic advantage ratio was 107.91 (95% confidence interval [CI] 22.22\u2013524.13), and the area under the summary receiver operating characteristics curve was 0.91 (95% CI 0.88\u20130.93). The overall heterogeneity of the studies is negligible (I2=0, 95% CI 0\u2013100). However, notable heterogeneity was observed in the combined specificity (P &lt;0.01, I2=74.82) and diagnostic odds ratio (P=0.05, I2=51.54). The heterogeneity in these aspects could be elucidated through sensitivity analysis.<\/jats:p><jats:p>\n            Conclusions Our analysis showed that CE-EUS is useful in identifying autoimmune pancreatitis. However, further large sample size, multicenter, prospective studies are needed to demonstrate its utility.<\/jats:p>","DOI":"10.1055\/a-2409-5519","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T23:04:34Z","timestamp":1728601474000},"page":"E1134-E1142","source":"Crossref","is-referenced-by-count":1,"title":["Contrast-enhanced endoscopic ultrasound for differential diagnosis of autoimmune pancreatitis: a meta-analysis"],"prefix":"10.1055","volume":"12","author":[{"given":"Shanshan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinguang","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghulam","family":"Nabi","sequence":"additional","affiliation":[{"name":"ENdocrinology and Physiology, Institute of Nature Conservation PAS, Krakow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangbin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingwen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changqing","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,10,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.gtc.2015.10.005","article-title":"Autoimmune pancreatitis: an update on diagnosis and management","volume":"45","author":"K Madhani","year":"2016","journal-title":"Gastroenterol Clin North Am"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"E66","DOI":"10.1055\/a-1293-7279","article-title":"Diagnostic yield of endoscopic ultrasound-guided tissue acquisition in autoimmune pancreatitis: a systematic review and meta-analysis","volume":"9","author":"A Facciorusso","year":"2021","journal-title":"Endosc Int Open"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"161","DOI":"10.14366\/usg.14017","article-title":"Contrast-enhanced endoscopic ultrasonography: advance and current status","volume":"33","author":"SI Jang","year":"2014","journal-title":"Ultrasonography (Seoul, Korea)"},{"key":"ref4","first-page":"1005","article-title":"The diagnosis of autoimmune pancreatitis using endoscopic ultrasonography","volume":"10","author":"A Kanno","year":"2020","journal-title":"Diagnostics (Basel, Switzerland)"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.gie.2007.07.045","article-title":"A novel perfusion imaging technique of the pancreas: contrast-enhanced harmonic EUS (with video)","volume":"67","author":"M Kitano","year":"2008","journal-title":"Gastrointest Endosc"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1111\/j.1478-3231.2010.02226.x","article-title":"Radiofrequency ablation guided by contrast harmonic sonography using perfluorocarbon microbubbles (Sonazoid) for hepatic malignancies: an initial experience","volume":"30","author":"Y Minami","year":"2010","journal-title":"Liver Int"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1007\/s003300000496","article-title":"Therapeutic effect of transcatheter arterial chemoembolization on hepatocellular carcinoma: evaluation with contrast-enhanced harmonic power Doppler ultrasound","volume":"10","author":"D Cioni","year":"2000","journal-title":"Eur Radiol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","article-title":"QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies","volume":"155","author":"PF Whiting","year":"2011","journal-title":"Ann Intern Med"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"2273","DOI":"10.1002\/sim.4780122405","article-title":"A bivariate approach to meta-analysis","volume":"12","author":"HC Van Houwelingen","year":"1993","journal-title":"Stat Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1002\/sim.1040","article-title":"Advanced methods in meta-analysis: multivariate approach and meta-regression","volume":"21","author":"HC Van Houwelingen","year":"2002","journal-title":"Stat Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/S1473-3099(12)70323-7","article-title":"Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis","volume":"13","author":"C Wacker","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"JP Higgins","year":"2002","journal-title":"Stat Med"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"MJ Page","year":"2021","journal-title":"BMJ"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1055\/s-0030-1256022","article-title":"Contrast-enhanced endoscopic ultrasound in the diagnosis of autoimmune pancreatitis","volume":"43","author":"M Hocke","year":"2011","journal-title":"Endoscopy"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.4103\/2303-9027.129519","article-title":"Vascular image in autoimmune pancreatitis by contrast-enhanced color-Doppler endoscopic ultrasonography: Comparison with pancreatic cancer","volume":"3","author":"G Kobayashi","year":"2014","journal-title":"Endosc Ultrasound"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"591","DOI":"10.5009\/gnl17391","article-title":"Contrast-enhanced endoscopic ultrasound for differentially diagnosing autoimmune pancreatitis and pancreatic cancer","volume":"12","author":"MK Cho","year":"2018","journal-title":"Gut Liver"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"196","DOI":"10.4103\/eus.eus_23_17","article-title":"Autoimmune pancreatitis: Imaging features","volume":"7","author":"Y Dong","year":"2018","journal-title":"Endosc Ultrasound"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"853","DOI":"10.3109\/00365521.2012.679686","article-title":"Novel quantitative perfusion analysis with contrast-enhanced harmonic EUS for differentiation of autoimmune pancreatitis from pancreatic carcinoma","volume":"47","author":"H Imazu","year":"2012","journal-title":"Scand J Gastroenterol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"AB246","DOI":"10.1016\/j.gie.2009.03.620","article-title":"Usefulness of endoscopic ultrasonography (plain combined with contrast-enhanced) in the differentiation between autoimmune pancreatitis and pancreatic cancer","volume":"69","author":"T Ishikawa","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"491782","DOI":"10.1155\/2015\/491782","article-title":"Contrast-enhanced endoscopic ultrasonography for pancreatic tumors","volume":"2015","author":"Y Yamashita","year":"2015","journal-title":"Biomed Res Int"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1016\/j.jclinepi.2005.01.016","article-title":"The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed","volume":"58","author":"JJ Deeks","year":"2005","journal-title":"J Clin Epidemiol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1097\/01.SLA.0000071516.54864.C1","article-title":"Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis","volume":"237","author":"JM Hardacre","year":"2003","journal-title":"Ann Surg"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1080\/00365520701529238","article-title":"Incidence of the focal type of autoimmune pancreatitis in chronic pancreatitis suspected to be pancreatic carcinoma: experience of a single tertiary cancer center","volume":"43","author":"M Kajiwara","year":"2008","journal-title":"Scand J Gastroenterol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/00000478-200301000-00012","article-title":"Pancreaticoduodenectomy (Whipple resections) in patients without malignancy: Are they all 'chronic pancreatitis'?","volume":"27","author":"SC Abraham","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.amjsurg.2006.08.064","article-title":"Pancreaticoduodenectomy for suspected malignancy: have advancements in radiographic imaging improved results?","volume":"192","author":"R Sasson A","year":"2006","journal-title":"Am J Surgery"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.amjsurg.2005.10.051","article-title":"Incidence of benign inflammatory disease in patients undergoing Whipple procedure for clinically suspected carcinoma: a single-institution experience","volume":"191","author":"T Kennedy","year":"2006","journal-title":"Am J Surg"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"4809","DOI":"10.3748\/wjg.v21.i16.4809","article-title":"New endoscopic ultrasound techniques for digestive tract diseases: A comprehensive review","volume":"21","author":"F-S Meng","year":"2015","journal-title":"World J Gastroenterol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1111\/den.13866","article-title":"Endoscopic ultrasound-guided fine needle aspiration versus biopsy for diagnosis of autoimmune pancreatitis: Systematic review and comparative meta-analysis","volume":"33","author":"SB Yoon","year":"2021","journal-title":"Digest Endosc"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/j.ultrasmedbio.2007.11.006","article-title":"Physicochemical characteristics of sonazoid, a new contrast agent for ultrasound imaging","volume":"34","author":"PC Sontum","year":"2008","journal-title":"J Ultrasound Med Biol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1440-1746.2010.06559.x","article-title":"Utility of contrast-enhanced ultrasonography with Sonazoid in radiofrequency ablation for hepatocellular carcinoma","volume":"26","author":"R Masuzaki","year":"2011","journal-title":"J Gastroenterol Hepatol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"66392","DOI":"10.18632\/oncotarget.18915","article-title":"Contrast-enhanced endoscopic ultrasound for differential diagnosis of pancreatic cancer: an updated meta-analysis","volume":"8","author":"XK He","year":"2017","journal-title":"J Oncotarget"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2409-5519.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T11:27:41Z","timestamp":1730806061000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2409-5519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":31,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,10,10]]},"published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2409-5519","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"type":"print","value":"2364-3722"},{"type":"electronic","value":"2196-9736"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}