{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:26Z","timestamp":1787004866703,"version":"build-2736575974"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Es wurden 3 Hunde mit pl\u00f6tzlich auftretenden erythemat\u00f6sen Hautver\u00e4nderungen,\n                    Fieber und weiteren unterschiedlichen extrakutanen Symptomen vorgestellt, welche\n                    mittels klinischer, labordiagnostischer und histopathologischer Untersuchungen\n                    der caninen sterilen neutrophilen Dermatose zugeordnet werden konnten. Die\n                    Erkrankung ist sehr selten und mit dem Sweet-Syndrom (SS) des Menschen zu\n                    vergleichen. Entsprechend den 4 Formen des SS konnte in dieser Kasuistik der 1.\n                    und 3. Fall dem klassischen\/idiopathischen SS zugeordnet werden, wobei die\n                    respiratorischen Symptome, als Prodromalstadium des SS, den Hautl\u00e4sionen\n                    vorausgingen oder eine Infektion des Respirationstraktes als Trigger des SS\n                    anzusprechen ist. Der 2. Fall hingegen weist einen deutlichen und der 3. Fall\n                    einen m\u00f6glichen Zusammenhang mit Pathergie als Folge einer vorausgegangen\n                    chirurgischen Versorgung (Fall 2 eine Tibia Plateau Leveling Osteotomy [TPLO] 20\n                    Tage zuvor; Fall 3 eine Hemilaminektomie 90 Tage zuvor) auf, wodurch beide der\n                    4. Form des SS zugeordnet werden k\u00f6nnen. Bei allen 3 F\u00e4llen ist eine adverse\n                    Arzneimittelreaktion als Trigger nicht sicher auszuschlie\u00dfen, da jeweils vor\n                    Diagnosestellung Medikamente eingesetzt wurden. Neben den h\u00e4ufigsten\n                    extrakutanen Symptomen wie Fieber und Neutrophilie, trat bei 2 der Patienten\n                    eine immunh\u00e4molytische An\u00e4mie auf. Als Therapieoptionen wird zus\u00e4tzlich zu den\n                    etablierten immunsupprimierenden Medikamenten wie Prednisolon, Ciclosporin und\n                    Azathioprin auch Oclacitinib in das Behandlungsschema mit aufgenommen, ebenso\n                    wie ein Thrombozytenaggregationshemmer (Clopidogrel), welcher als Lehre aus dem\n                    1. der vorliegenden F\u00e4lle zu deuten ist, der an einer pulmonalen Thromboembolie\n                    verstarb. Bei Fall 2 konnten alle Medikamente \u00fcber 2,5 Jahre ausgeschlichen\n                    werden, seit 4 Jahren ist der Patient ohne Rezidiv. Fall 3 ist unter Therapie\n                    rezidivfrei.<\/jats:p>","DOI":"10.1055\/a-2410-7191","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T18:30:25Z","timestamp":1729794625000},"page":"288-299","source":"Crossref","is-referenced-by-count":1,"title":["Canine neutrophile Dermatose (Sweet-like Syndrom): Eine Beschreibung\n                    von 3 F\u00e4llen"],"prefix":"10.1055","volume":"52","author":[{"given":"Sarah","family":"Sch\u00f6nbach","sequence":"additional","affiliation":[{"name":"Kleintierpraxis Aartalsee, Hohenahr"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Thom","sequence":"additional","affiliation":[{"name":"Abteilung Dermatologie, Klinik f\u00fcr Kleintiere, Innere Medizin,\n                    Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Mathes","sequence":"additional","affiliation":[{"name":"Kleintierpraxis Aartalsee, Hohenahr"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"von Broock","sequence":"additional","affiliation":[{"name":"Kleintierpraxis Aartalsee, Hohenahr"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"ref1","first-page":"711","volume-title":"Miscellaneous Skin Diseases. 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