{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:40:28Z","timestamp":1787964028665,"version":"build-2784847793"},"reference-count":76,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Crohn\u2019s disease (CD), also known as cicatrizing enteritis, is an inflammatory bowel disease that occurs in the distal ileum and right colon of unknown cause and is also called inflammatory bowel disease (IBD) with ulcerative colitis (UC). In recent years, intestinal biota have been confirmed to play a significant role in various gastrointestinal diseases. Studies have found that intestinal microbiota disorders are closely associated with the onset and progression of Crohn\u2019s disease. Bacteroidetes, the second largest microbiota in the intestine, are crucial for equilibrium in the microbiota and intestinal environment. Certain Bacteroides can induce the development of Crohn\u2019s disease and aggravate intestinal inflammation directly or through their metabolites. Conversely, certain Bacteroides can reduce intestinal inflammation and symptoms of Crohn\u2019s disease. This article reviews the effect of several intestinal Bacteroides in the onset and progression of Crohn\u2019s disease and their impact on its treatment.<\/jats:p>","DOI":"10.1055\/a-2435-2659","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T03:40:21Z","timestamp":1732592421000},"page":"393-402","source":"Crossref","is-referenced-by-count":4,"title":["Effect of Bacteroides on Crohn\u2019s disease"],"prefix":"10.1055","volume":"63","author":[{"given":"Xuanyu","family":"Wei","sequence":"additional","affiliation":[{"name":"Northern Jiangsu People\u2019s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Tang","sequence":"additional","affiliation":[{"name":"Northern Jiangsu People\u2019s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, China"},{"name":"Department of General Surgery, Institute of General Surgery, Northern Jiangsu People\u2019s Hospital, Nanjing University, Yangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2769","DOI":"10.1016\/S0140-6736(17)32448-0","article-title":"Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies","volume":"390","author":"SC Ng","year":"2017","journal-title":"Lancet"},{"issue":"03","key":"ref2","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/jgh.14872","article-title":"The epidemiology of inflammatory bowel disease: East meets west","volume":"35","author":"WY Mak","year":"2020","journal-title":"J Gastroenterol Hepatol"},{"issue":"02","key":"ref3","doi-asserted-by":"publisher","first-page":"113","DOI":"10.25122\/jml-2018-0075","article-title":"A review of the diagnosis, prevention, and treatment methods of inflammatory bowel disease","volume":"12","author":"SS Seyedian","year":"2019","journal-title":"J Med Life"},{"issue":"12","key":"ref4","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1038\/ng.717","article-title":"Genome-wide meta-analysis increases to 71 the number of confirmed Crohn\u2019s disease susceptibility loci","volume":"42","author":"A Franke","year":"2010","journal-title":"Nat Genet"},{"issue":"12","key":"ref5","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.3109\/00365521.2010.510575","article-title":"Environmental risk factors in inflammatory bowel diseases. 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