{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:28:26Z","timestamp":1791296906389,"version":"4.1.0"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"name":"European Union's Horizon Europe Research and Innovation Program","award":["10113624"],"award-info":[{"award-number":["10113624"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1055\/a-2438-5671","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T19:01:19Z","timestamp":1728932479000},"page":"007-011","source":"Crossref","is-referenced-by-count":42,"title":["TARGET: A Major European Project Aiming to Advance the Personalised Management of Atrial Fibrillation-Related Stroke via the Development of Health Virtual Twins Technology and Artificial Intelligence"],"prefix":"10.1055","volume":"125","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9927-3209","authenticated-orcid":false,"given":"Sandra","family":"Ortega-Martorell","sequence":"additional","affiliation":[{"name":"Data Science Research Centre, Liverpool John Moores University, Liverpool, United Kingdom"},{"name":"Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5679-7501","authenticated-orcid":false,"given":"Ivan","family":"Olier","sequence":"additional","affiliation":[{"name":"Data Science Research Centre, Liverpool John Moores University, Liverpool, United Kingdom"},{"name":"Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1145-4297","authenticated-orcid":false,"given":"Mattias","family":"Ohlsson","sequence":"additional","affiliation":[{"name":"Computational Science for Health and Environment, Centre for Environmental and Climate Science, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7566-1626","authenticated-orcid":false,"given":"Gregory Y.H.","family":"Lip","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom"},{"name":"Department of Clinical Medicine, Danish Center for Health Services Research, Aalborg University, Aalborg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the TARGET Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,11,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"100786","DOI":"10.1016\/j.lanepe.2023.100786","article-title":"Atrial fibrillation: epidemiology, screening and digital health","volume":"37","author":"D Linz","year":"2024","journal-title":"Lancet Reg Health Eur"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-024-03007-9","article-title":"Clinical outcomes of patients with atrial fibrillation in relation to multimorbidity status changes over time and the impact of ABC pathway compliance: a nationwide cohort study","author":"R Krittayaphong","year":"2024","journal-title":"J Thromb Thrombolysis"},{"issue":"10","key":"ref3","first-page":"835","article-title":"Dynamic assessment of CHA2DS2-VASc and HAS-BLED scores for predicting ischemic stroke and major bleeding in atrial fibrillation patients","volume":"77","author":"M J Serna","year":"2024","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1055\/s-0043-1776394","article-title":"Sex as a risk factor for atrial fibrillation-related stroke","volume":"124","author":"B Corica","year":"2024","journal-title":"Thromb Haemost"},{"issue":"20","key":"ref5","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1093\/eurheartj\/ehae198","article-title":"Ischaemic stroke in women with atrial fibrillation: temporal trends and clinical implications","volume":"45","author":"K Teppo","year":"2024","journal-title":"Eur Heart J"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"100967","DOI":"10.1016\/j.lanepe.2024.100967","article-title":"Comparing CHA2DS2-VA and CHA2DS2-VASc scores for stroke risk stratification in patients with atrial fibrillation: a temporal trends analysis from the retrospective Finnish AntiCoagulation in Atrial Fibrillation (FinACAF) cohort","volume":"43","author":"K Teppo","year":"2024","journal-title":"Lancet Reg Health Eur"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.1093\/eurheartj\/ehae540","article-title":"CHA2DS2-VASc or a non-sex score (CHA2DS2-VA) for stroke risk prediction in atrial fibrillation: contemporary insights and clinical implications","volume":"45","author":"G YH Lip","year":"2024","journal-title":"Eur Heart J"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"6728","DOI":"10.1038\/s41467-024-51193-0","article-title":"Risk of stroke in male and female patients with atrial fibrillation in a nationwide cohort","volume":"15","author":"P B Nielsen","year":"2024","journal-title":"Nat Commun"},{"issue":"11","key":"ref9","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1055\/s-0043-1769612","article-title":"Mobile health-technology-integrated care for atrial fibrillation: a win ratio analysis from the mAFA-II randomized clinical trial","volume":"123","author":"G F Romiti","year":"2023","journal-title":"Thromb Haemost"},{"issue":"03","key":"ref10","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1055\/a-1515-9630","article-title":"Adherence to the \u2018atrial fibrillation better care\u2019 pathway in patients with atrial fibrillation: impact on clinical outcomes-a systematic review and meta-analysis of 285,000 patients","volume":"122","author":"G F Romiti","year":"2022","journal-title":"Thromb Haemost"},{"issue":"01","key":"ref11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jacc.2023.08.017","article-title":"2023 ACC\/AHA\/ACCP\/HRS guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines","volume":"83","author":"J A Joglar","year":"2024","journal-title":"J Am Coll Cardiol"},{"issue":"01","key":"ref12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1055\/s-0041-1739411","article-title":"2021 focused update consensus guidelines of the Asia Pacific Heart Rhythm Society on stroke prevention in atrial fibrillation: executive summary","volume":"122","author":"T F Chao","year":"2022","journal-title":"Thromb Haemost"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"100797","DOI":"10.1016\/j.lanepe.2023.100797","article-title":"Atrial fibrillation: stroke prevention","volume":"37","author":"T F Chao","year":"2024","journal-title":"Lancet Reg Health Eur"}],"container-title":["Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2438-5671.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T18:43:40Z","timestamp":1735929820000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2438-5671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,14]]},"references-count":13,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2025,1,3]]},"published-print":{"date-parts":[[2025,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2438-5671","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0340-6245","2567-689X"],"issn-type":[{"value":"0340-6245","type":"print"},{"value":"2567-689X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,10,14]]},"published":{"date-parts":[[2024,10,14]]}}}