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The present case series describes three patients suffering from ANE secondary to influenza A\/H1N1 infection during a recent outbreak, treated with increasingly aggressive anti-inflammatory approach, and with significantly different outcomes.<\/jats:p>","DOI":"10.1055\/a-2442-5810","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T19:03:16Z","timestamp":1729191796000},"page":"259-264","source":"Crossref","is-referenced-by-count":3,"title":["Management of Critically Ill Children with Acute Necrotizing Encephalitis during an H1N1 Outbreak in a Tertiary Pediatric Hospital: A Series of Three Cases and Literature Review"],"prefix":"10.1055","volume":"56","author":[{"given":"Annalisa","family":"D'Eleuterio","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care, Pediatric Intensive Care Unit, Meyer Children's Hospital IRCCS, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Rufini","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care, Pediatric Intensive Care Unit, Meyer Children's Hospital IRCCS, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"L'Erario","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care, Pediatric Intensive Care Unit, Meyer Children's Hospital IRCCS, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Simonini","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Rheumatology Unit, ERN ReCONNET Center, Meyer Children's Hospital IRCCS, Florence, Italy"},{"name":"Department of Neuroscience, Meyer Children's Hospital IRCCS, Florence, 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