{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T04:37:42Z","timestamp":1778301462032,"version":"3.51.4"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"11","license":[{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n            Background and study aims Bowel obstruction is a common complication in advanced cancer patients. Patients are restricted in quality of life (QOL) due to nausea, vomiting, or abdominal pain. Prospective data on the feasibility and benefit of decompressive percutaneous endoscopic gastrostomy (dPEG) are scarce.<\/jats:p><jats:p>\n            Patients and methods Patients suffering from symptomatic bowel obstruction due to advanced cancer were included prospectively in a single-center study when other treatments to eliminate the obstruction were impossible. Patients were given a questionnaire the day before dPEG (d-1) and, if the procedure was successful, the day after (d+1) and 14 days after the procedure (d14). Furthermore, lifetime after dPEG was assessed.<\/jats:p><jats:p>\n            Results 53 patients were included. dPEG was technically feasible\n      in 34 of 53 (64.2%). Significant improvement could be shown for nausea and vomiting when\n      comparing d-1 to d+1 (nausea (P = 0.002), vomiting (P &lt; 0.001)) and when comparing d-1 to d14 (P = 0.021 and P = 0.003, respectively). Comparing d+1 to\n      d14, there was no further improvement. QOL improved significantly from 8.1 (mean) on d-1 to\n      5.9 (mean) on d+1 (P &lt; 0.001). Median survival after successful\n      dPEG was 27 days (range 2\u2013353).<\/jats:p><jats:p>\n            Conclusions dPEG is an effective method for quickly relieve symptoms of malignant bowel obstruction in advanced cancer patients. However, the technical success rate is limited and needs to be improved. Prospective studies comparing endoscopic and computed tomography-guided procedures are needed to avoid unsuccessful procedures in patients with advanced cancer and limited life expectancy.<\/jats:p>","DOI":"10.1055\/a-2458-9919","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:40:54Z","timestamp":1732840854000},"page":"E1411-E1416","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility and benefit of decompressive percutaneous endoscopic gastrostomy (dPEG) in advanced cancer patients with malignant bowel obstruction"],"prefix":"10.1055","volume":"12","author":[{"given":"Julia","family":"Wanzl","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Hospital Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"H\u00f6fer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Schwamberger","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vidan","family":"Tadic","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Muzalyova","sequence":"additional","affiliation":[{"name":"Department of Digital Medicine, University Hospital Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irmtraut","family":"Hainsch-M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, University of Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Aulmann","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, University of Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmut","family":"Messmann","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Probst","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Augsburg, Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"159","DOI":"10.2147\/CMAR.S29297","article-title":"Malignant bowel obstruction in advanced cancer patients: epidemiology, management, and factors influencing spontaneous resolution","volume":"4","author":"A Tuca","year":"2012","journal-title":"Cancer Manag Res"},{"key":"ref2","first-page":"353","article-title":"Small-bowel obstruction secondary to malignant disease: an 11-year audit","volume":"43","author":"G Miller","year":"2000","journal-title":"Can J Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.jpainsymman.2008.01.014","article-title":"Efficacy of granisetron in the antiemetic control of nonsurgical intestinal obstruction in advanced cancer: a phase II clinical trial","volume":"37","author":"A Tuca","year":"2009","journal-title":"J Pain Symptom Manage"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s00520-021-06438-9","article-title":"Management of bowel obstruction in advanced cancer","volume":"6","author":"C Ripamonti","year":"1994","journal-title":"Curr Opin Oncol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1046\/j.1525-1438.2002.01103.x","article-title":"Palliative management of malignant bowel obstruction","volume":"12","author":"C Ripamonti","year":"2002","journal-title":"Int J Gynecol Cancer"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"8089","DOI":"10.1007\/s00520-021-06438-9","article-title":"Medical management of malignant bowel obstruction in patients with advanced cancer: 2021 MASCC guideline update","volume":"29","author":"M Davis","year":"2021","journal-title":"Support Care Cancer"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e3400","DOI":"10.1590\/1518-8345.3355.3400","article-title":"Nasogastric\/nasoenteric tube-related adverse events: an integrative review","volume":"29","author":"APG Motta","year":"2021","journal-title":"Rev Lat Am Enfermagem"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1006\/gyno.1996.0197","article-title":"Palliative treatment of upper intestinal obstruction by gynecological malignancy: the usefulness of percutaneous endoscopic gastrostomy","volume":"62","author":"E Campagnutta","year":"1996","journal-title":"Gynecol Oncol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3949\/ccjm.78a.10052","article-title":"Malignant bowel obstruction: individualized treatment near the end of life","volume":"78","author":"A Soriano","year":"2011","journal-title":"Cleve Clin J Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1016\/s0022-3468(80)80296-x","article-title":"Gastrostomy without laparotomy: a percutaneous endoscopic technique","volume":"15","author":"MW Gauderer","year":"1980","journal-title":"J Pediatr Surg"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1016\/j.gie.2009.10.027","article-title":"A lexicon for endoscopic adverse events: report of an ASGE workshop","volume":"71","author":"PB Cotton","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1007\/s00464-013-3368-7","article-title":"Palliative venting percutaneous endoscopic gastrostomy tube is safe and effective in patients with malignant obstruction","volume":"28","author":"RB Issaka","year":"2014","journal-title":"Surg Endosc"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/s0016-5107(92)70423-4","article-title":"Percutaneous endoscopic gastrostomy for decompression of the stomach and small bowel","volume":"38","author":"LL Herman","year":"1992","journal-title":"Gastrointest Endosc"},{"key":"ref14","first-page":"1946","article-title":"Ultrasound-assisted percutaneous endoscopic gastrostomy in a patient with advanced ovarian carcinoma and recurrent intestinal obstruction","volume":"88","author":"JJ Vargo","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/s0016-5107(95)70253-9","article-title":"Endoscopic ultrasound in the placement of a percutaneous endoscopic gastrostomy tube in the non-transilluminated abdominal wall","volume":"42","author":"S Panzer","year":"1995","journal-title":"Gastrointest Endosc"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"464","DOI":"10.5152\/dir.2020.19471","article-title":"CT-guided gastrostomy tube placement-a single center case series","volume":"26","author":"JT Yasin","year":"2020","journal-title":"Diagn Interv Radiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"95","DOI":"10.4103\/1319-3767.93808","article-title":"Percutaneous endoscopic gastrostomy tube placement for end-stage palliation of malignant gastrointestinal obstructions","volume":"18","author":"A Teriaky","year":"2012","journal-title":"Saudi J Gastroenterol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1007\/s00520-017-3700-1","article-title":"Benefits and risks of a percutaneous endoscopic gastrostomy (PEG) for decompression in patients with malignant gastrointestinal obstruction","volume":"25","author":"A Dittrich","year":"2017","journal-title":"Support Care Cancer"},{"key":"ref19","first-page":"2877","article-title":"Decompressive percutaneous endoscopic gastrostomy in advanced cancer patients with small-bowel obstruction is feasible and effective: a large prospective study","volume":"24","author":"E Zucchi","year":"2016","journal-title":"Support Care Cancer"},{"key":"ref20","first-page":"573","article-title":"Percutaneous endoscopic gastrostomy for gastric decompression in metastatic gynecologic malignancies","volume":"177","author":"WH Marks","year":"1993","journal-title":"Surg Gynecol Obstet"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1002\/jso.25499","article-title":"Timing of palliative care: When to call for a palliative care consult","volume":"120","author":"CJR Schlick","year":"2019","journal-title":"J Surg Oncol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1016\/j.giec.2007.07.002","article-title":"Palliative use of percutaneous endoscopic gastrostomy and percutaneous endoscopic cecostomy tubes","volume":"17","author":"AN Holm","year":"2007","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.ygyno.2004.09.058","article-title":"Percutaneous endoscopic gastrostomy tube placement in patients with malignant bowel obstruction due to ovarian carcinoma","volume":"96","author":"B Pothuri","year":"2005","journal-title":"Gynecol Oncol"},{"key":"ref24","first-page":"648","article-title":"Palliation of gastrointestinal obstruction","volume":"58","author":"G Tradounsky","year":"2012","journal-title":"Can Fam Physician"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15184540","article-title":"CT fluoroscopy-guided percutaneous gastrostomy in the palliative management of advanced and relapsed ovarian cancer: the Charite experiences and a review of the literature","volume":"15","author":"E Canaz","year":"2023","journal-title":"Cancers (Basel)"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2458-9919.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:41:26Z","timestamp":1732840886000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2458-9919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":25,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,7]]},"published-print":{"date-parts":[[2024,11]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2458-9919","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}