{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:02:03Z","timestamp":1784030523225,"version":"3.55.0"},"reference-count":55,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Reconstr Microsurg"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Upper extremity (UE) replantation and revascularization are challenging surgical procedures, with survival rates being 50 to 90%. Preoperative risk stratification is challenging yet crucial as patients with comorbid conditions face increased complications. This study assesses the predictive value of the modified 5-item frailty index (5-mFI) for postoperative complications in these procedures.<\/jats:p><jats:p>A retrospective study was done using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database (2011\u20132021) for UE replantation\/revascularization. The 5-mFI score assigned points for comorbidities including pulmonary disease, heart failure, diabetes, hypertension, and functional status (0\u20135 scale; 1 point to each). 5-mFI scores stratified patients into &lt;2 (low-risk) or \u22652 (high-risk) categories.<\/jats:p><jats:p>Of 2,305 patients, the mean age and body mass index (BMI) were 53.13 years and 28.53\u2009kg\/m2, respectively. The 5-mFI \u22652 cohort experienced higher rates of all-cause complications, systemic complications, unplanned readmissions, and return to the operating room on univariate analysis. There was no significant difference in wound complication rates. Multivariable logistic regression showed that a higher 5-mFI was significantly associated with increased risks of all-cause mild and severe systemic complications. Wound complications, length of stay over 30 days, unplanned readmission, and return to the operating room were higher in high-risk patients, however not statistically significant.<\/jats:p><jats:p>5-mFI is an effective tool for evaluating risk in UE replantation and revascularization, correlating high scores with significantly increased postoperative complications. High-risk patients with 5-mFI \u22652 also had more reoperations and readmissions. The use of 5-mFI in preoperative assessments can help personalize management, enhancing patient selection and care quality in these complex reconstructions.<\/jats:p>","DOI":"10.1055\/a-2460-4706","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T20:16:47Z","timestamp":1730751407000},"page":"557-565","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of Modified Frailty Index for Predicting Postoperative Outcomes after Upper Extremity Replantation and Revascularization Procedures"],"prefix":"10.1055","volume":"41","author":[{"given":"Anshumi","family":"Desai","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami, Miami, Florida"},{"name":"University of Miami Miller School of Medicine, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Luo","sequence":"additional","affiliation":[{"name":"University of Miami Miller School of Medicine, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Borowsky","sequence":"additional","affiliation":[{"name":"University of Miami Miller School of Medicine, Miami, Florida"},{"name":"Division of Surgical Oncology, DeWitt Daughtry Family Department of Surgery, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria P.","family":"Bustos","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami, Miami, Florida"},{"name":"University of Miami Miller School of Medicine, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Fullerton","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami, Miami, Florida"},{"name":"University of Miami Miller School of Medicine, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle Y.","family":"Xu","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami, Miami, Florida"},{"name":"University of Miami Miller School of Medicine, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kashyap K.","family":"Tadisina","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami, Miami, Florida"},{"name":"University of Miami 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