{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T22:37:26Z","timestamp":1761345446547,"version":"build-2065373602"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Objectives\u2003This study aims to fill in the knowledge gap about patients with occipital condyle fractures (OCFs) and cranial nerve dysfunction (CND) and give advice about when to test the cranial nerves (CNs) and what to do when CND is diagnosed.<\/jats:p>\n                  <jats:p>Design\u2003A 14-year period observational, retrospective cohort study.<\/jats:p>\n                  <jats:p>Setting\u2003Level-I trauma center study.<\/jats:p>\n                  <jats:p>Participants\u2003All 119 surviving cases admitted with an OCF, whereof all 40 cases with either diagnosed CND (confirmed by clinical examination) or expected CND (reported observations high suspicious for CND) were selected for detailed data collection. Early death was the only exclusion criterion because of missing data and clinical irrelevance.<\/jats:p>\n                  <jats:p>Main Outcome Measures\u2003One-third of all surviving OCF patients have CND (n\u2009=\u200940\/119, 33.6%), where three-quarters had more than one CN affected with a median of three CNs. Of the cases with a concomitant lateral skull base fracture (n\u2009=\u200924\/40, 60%), one in three cases (36%, n\u2009=\u200913\/36) had facial nerve palsy and nearly two in three cases (61%, n\u2009=\u200922\/36) had hearing loss.<\/jats:p>\n                  <jats:p>Results\u2003The facial nerve was the most commonly diagnosed CND. Solitary OCF cases often had lower CND (n\u2009=\u200911\/14). Fifty-eight percent of all CND cases with follow-up data (n\u2009=\u200919\/33)\u2014corresponding to one in six of all surviving OCF cases\u2014had chronic CND sequelae.<\/jats:p>\n                  <jats:p>Conclusion\u2003Multiple and chronic CND is common in patients with an OCF. All CNs should be tested in those patients as soon as clinically possible, and testing should be repeated after 3 to 7 days and before discharge. Patients with CND should be counseled about their prognosis and be potentially referred to (e.g.) a speech and language therapist, ophthalmologist, neurologist, or otorhinolaryngologist for early treatment options.<\/jats:p>","DOI":"10.1055\/a-2461-5391","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T19:06:54Z","timestamp":1732648014000},"page":"e8-e16","source":"Crossref","is-referenced-by-count":0,"title":["Cranial Nerve Dysfunction in Patients with an Occipital Condyle Fracture: Underdiagnosis and Clinical Relevance"],"prefix":"10.1055","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0928-4882","authenticated-orcid":false,"given":"Madelon","family":"Thevis","sequence":"additional","affiliation":[{"name":"Dutch Academic Alliance Skull Base Pathology, Radboud University Medical Centre, Maastricht University Medical Centre\u2009+\u2009, Nijmegen\/Maastricht, The Netherlands"},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands"},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Maastricht University Medical Centre\u00fe, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jolanda","family":"Derks","sequence":"additional","affiliation":[{"name":"Dutch Academic Alliance Skull Base Pathology, Radboud University Medical Centre, Maastricht University Medical Centre\u2009+\u2009, Nijmegen\/Maastricht, The Netherlands"},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thijs T.G.","family":"Jansen","sequence":"additional","affiliation":[{"name":"Dutch Academic Alliance Skull Base Pathology, Radboud University Medical Centre, Maastricht University Medical Centre\u2009+\u2009, Nijmegen\/Maastricht, The Netherlands"},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allard J.F.","family":"Hosman","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic surgery, Radboud University Medical Centre, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henricus P.M.","family":"Kunst","sequence":"additional","affiliation":[{"name":"Dutch Academic Alliance Skull Base Pathology, Radboud University Medical Centre, Maastricht University Medical Centre\u2009+\u2009, Nijmegen\/Maastricht, The Netherlands"},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands"},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Maastricht University Medical Centre\u00fe, Maastricht, The 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