{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T22:33:40Z","timestamp":1764282820049,"version":"3.46.0"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Padiatr"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die Muskeldystrophie Typ Duchenne ist die h\u00e4ufigste erbliche Muskelerkrankung im\n                    Kindesalter. Neben der progredienten Einschr\u00e4nkung der Motorik und der kardialen\n                    Beteiligung stehen die aus der Muskelschw\u00e4che resultierende restriktive\n                    Lungenerkrankung und die Hustenschw\u00e4che im Vordergrund. Die spezifische\n                    kinderpneumologische Therapie hat das \u00dcberleben und die Lebensqualit\u00e4t der\n                    betroffenen Jungen ma\u00dfgeblich verbessert. Zu den Aufgaben des Kinder-Pneumologen\n                    geh\u00f6ren das Monitoring der Lungenfunktion, die Polysomnographie, der Beginn und\n                    die Anpassung der nichtinvasiven oder invasiven n\u00e4chtlichen Beatmung und die\n                    Optimierung des Sekretmanagements. Aber auch die Komplettierung der Impfungen,\n                    die Ern\u00e4hrungstherapie, die Behandlung interkurrierender Atemwegsinfektionen\n                    sowie die Beratung und Schulung sind wichtige Aufgaben des Kinder-Pneumologen.\n                    In diesem Beitrag werden die Aspekte der pneumologischen Behandlung von Kindern\n                    mit neuromuskul\u00e4ren Erkrankungen am Beispiel der Muskeldystrophie Typ Duchenne\n                    im Zusammenspiel mit den anderen Fachdisziplinen aufgezeigt.<\/jats:p>","DOI":"10.1055\/a-2464-6210","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T19:01:16Z","timestamp":1733857276000},"page":"59-65","source":"Crossref","is-referenced-by-count":0,"title":["Kinderpneumologische Aspekte bei der Betreuung von Kindern mit\n                    neuromuskul\u00e4ren Erkrankungen am Beispiel der Muskeldystrophie Typ\n                    Duchenne"],"prefix":"10.1055","volume":"237","author":[{"given":"Hans","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Sektion Neonatologie und P\u00e4d. P\u00e4d. Intensivmedizin, P\u00e4d. Pneumologie,\n                    Zentrum f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Freiburg,\n                    Medizinische Fakult\u00e4t, Albert-Ludwigs-Universit\u00e4t Freiburg, Freiburg,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennart","family":"Gunst","sequence":"additional","affiliation":[{"name":"Sektion Neonatologie und P\u00e4d. P\u00e4d. Intensivmedizin, P\u00e4d. Pneumologie,\n                    Zentrum f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Freiburg,\n                    Medizinische Fakult\u00e4t, Albert-Ludwigs-Universit\u00e4t Freiburg, Freiburg,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anke","family":"Wendt","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Intensivmedizin, Klinik f\u00fcr P\u00e4diatrie mit Schwerpunkt\n                    Pneumologie, Immunologie und Intensivmedizin, Charit\u00e9 Universit\u00e4tsmedizin\n                    Berlin, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Becker","sequence":"additional","affiliation":[{"name":"Kinderpneumologie, Darmst\u00e4dter Kinderkliniken Prinzessin Margaret,\n                    Darmstadt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth Margarethe","family":"Grychtol","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Pneumologie, Klinik f\u00fcr P\u00e4diatrische Pneumologie,\n                    Allergologie und Neonatologie, Medizinische Hochschule Hannover, Hannover,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dejan","family":"Vlajnic","sequence":"additional","affiliation":[{"name":"Kinderpalliativzentrum, Vestische Kinder- und Jugendklinik Datteln,\n                    Deutschland, Universit\u00e4t Witten Herdecke, Datteln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorit","family":"Aschmann-Muehlhans","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Pneumologie, Kinderkrankenhaus St. Marien, Landshut,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane","family":"Wuerfel","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Pneumologie, Klinik und Poliklinik f\u00fcr Kinder- und\n                    Jugendmedizin, Medizinische Fakult\u00e4t und Universit\u00e4tsklinikum Carl Gustav Carus,\n                    Technische Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathis","family":"Steindor","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Pneumologie, Klinik f\u00fcr Kinderheilkunde III,\n                    Universit\u00e4tsklinikum Essen, Universit\u00e4t Duisburg-Essen, Essen,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Stehling","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Pneumologie, Klinik f\u00fcr Kinderheilkunde III,\n                    Universit\u00e4tsklinikum Essen, Universit\u00e4t Duisburg-Essen, Essen,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,12,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.ijbiomac.2024.130544","article-title":"A review on mechanistic insights into structure and function of dystrophin\n                    protein in pathophysiology and therapeutic targeting of Duchenne muscular\n                    dystrophy","author":"A M Elasbali","year":"2024","journal-title":"Int J Biol Macromol"},{"key":"ref2","first-page":"4","article-title":"Drug treatment of Duchenne muscular dystrophy: available evidence and\n                    perspectives","volume":"31","author":"Angeles de los","year":"2012","journal-title":"Acta Myol Myopathies Cardiomyopathies Off J Mediterr Soc\n                    Myol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.ejpn.2024.07.003","article-title":"Early motor, cognitive, language, 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