{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:09:41Z","timestamp":1777918181787,"version":"3.51.4"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Einleitung Ziel der Studie war es, die Wirksamkeit von Cerclagen bei\n                    Frauen mit belasteter Anamnese zu evaluieren. Das prim\u00e4re Ziel war die\n                    Verl\u00e4ngerung der Schwangerschaft und das Erreichen einer Termingeburt. Sekund\u00e4r\n                    wurde untersucht, ob eine Intervention nach einem fr\u00fchen pathologischen\n                    75-g-oGTT-Befund diese Endpunkte beeinflusst.<\/jats:p><jats:p>\n          Methodik Es wurden 133 F\u00e4lle retrospektiv analysiert. 80 Frauen erhielten\n                    eine prim\u00e4re Cerclage zwischen der 14.\u201316. Schwangerschaftswoche, 53 Frauen eine\n                    sekund\u00e4re Cerclage nach Zervixverk\u00fcrzung unter 25 mm. Diese Gruppe wurde weiter\n                    unterteilt in eine therapeutische und eine Notfallgruppe. Frauen mit fr\u00fchem\n                    pathologischem 75-g-oGTT wurden diabetologisch mitbetreut.<\/jats:p><jats:p>\n          Ergebnisse Die prim\u00e4re Cerclage verl\u00e4ngerte die Schwangerschaft um 20,6\n                    Wochen und f\u00fchrte bei 51 Frauen (63,8%) zu einer Termingeburt. In der Gruppe mit\n                    sekund\u00e4rer Cerclage kam es bei 25 Frauen (47,2%) zu einer Termingeburt mit einer\n                    Verl\u00e4ngerung um 20,1 Wochen. Bei einem Fruchtblasenprolaps betrug die\n                    Verl\u00e4ngerung 7,9 Wochen. Pathologische 75-g-oGTT-Ergebnisse hatten 63 Frauen.\n                    Eine fr\u00fchzeitige Intervention hatte keinen signifikanten Einfluss auf die\n                    Verl\u00e4ngerung und die Termingeburt.<\/jats:p><jats:p>\n          Schlussfolgerung Die prim\u00e4re Cerclage war effektiver f\u00fcr das Erreichen\n                    einer Termingeburt. Frauen mit therapeutischer Cerclage ohne Fruchtblasenprolaps\n                    profitierten ebenfalls. Bei Zervixverk\u00fcrzung ohne Prolaps war die Verl\u00e4ngerung\n                    in beiden Gruppen gleich. Das schlechteste Ergebnis wurde bei Notfallcerclage\n                    mit Fruchtblasenprolaps beobachtet. Ein fr\u00fchzeitiger 75-g-oGTT ist wichtig, um\n                    einen Gestationsdiabetes rechtzeitig zu erkennen und zu behandeln. <\/jats:p>","DOI":"10.1055\/a-2467-8698","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:08:12Z","timestamp":1733270892000},"page":"99-107","source":"Crossref","is-referenced-by-count":1,"title":["Prim\u00e4re und sekund\u00e4re Cerclage bei Hochrisiko-Schwangeren: Einfluss\n                    auf die Schwangerschaftsdauer und Fr\u00fchgeburt"],"prefix":"10.1055","volume":"229","author":[{"given":"Filiz","family":"Markfeld-Erol","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Medizinische\n                    Universit\u00e4tsklinik, Universit\u00e4tsklinikum Freiburg, Freiburg im Breisgau,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Meschede","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Medizinische\n                    Universit\u00e4tsklinik, Universit\u00e4tsklinikum Freiburg, Freiburg im Breisgau,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Klar","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Medizinische\n                    Universit\u00e4tsklinik, Universit\u00e4tsklinikum Freiburg, Freiburg im Breisgau,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingolf","family":"Juhasz-B\u00f6ss","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Medizinische\n                    Universit\u00e4tsklinik, Universit\u00e4tsklinikum Freiburg, Freiburg im Breisgau,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjam","family":"Kunze","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Medizinische\n                    Universit\u00e4tsklinik, Universit\u00e4tsklinikum Freiburg, Freiburg im Breisgau,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,12,3]]},"reference":[{"key":"ref1","first-page":"1","article-title":"Births. Final data for 2011","volume":"28","author":"J A Martin","year":"2013","journal-title":"Natl Vital Stat Rep"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1186\/1742-4755-12-S2-S6","article-title":"Neonatal mortality and coverage of essential newborn interventions 2010\u20132013: a\n                    prospective, population-based study from low-middle income countries","volume":"12","author":"S M Dhaded","year":"2015","journal-title":"Reprod Health"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jogc.2017.08.036","article-title":"What Interventions Are Being Used to Prevent Preterm Birth and When?","volume":"40","author":"Y Y Feng","year":"2018","journal-title":"J Obstet Gynaecol Can"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.ajog.2010.05.042","article-title":"Every 30 seconds a baby dies of preterm birth. What are you doing about it?","volume":"203","author":"V Berghella","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/uog.17457","article-title":"Cerclage for sonographic short cervix in singleton gestations without prior\n                    spontaneous preterm birth:systematic review and meta-analysis of randomized\n                    controlled trials using individual patient-level data","volume":"50","author":"V Berghella","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/OGX.0b013e318270d5b2","article-title":"Universal cervical length screening for prediction and prevention of preterm\n                    birth","volume":"67","author":"V Berghella","year":"2012","journal-title":"Obstet Gynecol Surv"},{"key":"ref7","first-page":"299","article-title":"A new method of operative treatmentfor habitual abortion in the second trimester\n                    of pregnancy","volume":"52","author":"V N Shirodkar","year":"1955","journal-title":"Antiseptic"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1471-0528.1957.tb02650.x","article-title":"Suture of the cervix for inevitable mis-carriage","volume":"64","author":"I A McDonald","year":"1957","journal-title":"J Obstet Gynaecol Br Emp"},{"key":"ref9","first-page":"1083","article-title":"Vollst\u00e4ndiges Zusammenn\u00e4hen des \u00e4u\u00dferen Muttermundes auf blutigem Wege zur\n                    Verhinderung von fortgeschrittenem Abortus und Fr\u00fchgeburten","volume":"83","author":"B Szendi","year":"1961","journal-title":"Zentralbl Gyn\u00e4kol"},{"key":"ref10","first-page":"259","article-title":"Der fr\u00fche totale Muttermundverschlu\u00df zur Vermeidung habitueller Aborte und\n                    Fr\u00fchgeburten","volume":"185","author":"E Saling","year":"1981","journal-title":"Z Geburtsh Perinat"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/AOG.0b013e31821fd5b0","article-title":"Cervical length screening with ultrasound-indicated cerclage for prevention of\n                    preterm birth: a meta-analysis","volume":"118","author":"V Berghella","year":"2011","journal-title":"Obstet Gynecol"},{"key":"ref13","first-page":"830","article-title":"A randomized trial of cerclage versus no cerclage among patients with\n                    ultrasonographically detected second-trimester preterm dilatation of the\n                    internal os","volume":"183","author":"O A Rust","year":"2000","journal-title":"YMOB"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1016\/S0140-6736(04)16351-4","article-title":"Cervical cerclage for prevention of preterm delivery in women with short cervix:\n                    randomized controlled trial","volume":"363","author":"M S To","year":"2004","journal-title":"Lancet"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/AOG.0b013e31821fd5b0","article-title":"Cervical length screening with ultrasound-indicated cerclage for prevention of\n                    preterm birth: a meta-analysis","volume":"118","author":"V Berghella","year":"2011","journal-title":"Obstet Gynecol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"483.e1","DOI":"10.1016\/j.ajog.2007.05.041","article-title":"Expectant management compared with physical examination-indicated cerclage in\n                    selected women with a dilated cervix at weeks: results from eht EM-PEC\n                    international cohort study","volume":"197","author":"L Pereira","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/OGX.0b013e31828737c7","article-title":"Emergency cerclage: literature review","volume":"68","author":"S Namouz","year":"2013","journal-title":"Obstet Gynecol Surv"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1097\/GRF.0000000000000197","article-title":"Emergency Cerclage: Outcomes Patient Selection, and operative\n                    Considerations","volume":"59","author":"M Naqvi","year":"2016","journal-title":"Clin Obstet Gynecol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1111\/aogs.13968","article-title":"Emergency cerclage in singleton pregnancies with painless cervical dilation:\n                    Ameta-analysis","volume":"99","author":"C Chatzakis","year":"2020","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1055\/s-2006-958165","article-title":"Shirodkar versus McDonald cerclage for the prevention of preterm birth in women\n                    with short cervical length","volume":"24","author":"A O Odibo","year":"2007","journal-title":"Am J Perinatol"},{"key":"ref22","first-page":"143","article-title":"Total cervix occlusion-an efficient measure in prolapsed amniotic membranes in\n                    extreme prematurity","volume":"205","author":"K T Schneider","year":"2001","journal-title":"Z. Geburtshilfe Neonatl"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/1471-0528.12119","article-title":"Randomised trial of cervical cerclage, with and without occlusion, for the\n                    prevention of preterm birth in women, suspected of cervical insufficiency","author":"N Brix","year":"2013","journal-title":"BJOG"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"dc231667","DOI":"10.2337\/dc23-1667.","article-title":"TOBOGM Research Group. Perinatal Outcomes in Early and Late Gestational Diabetes\n                    Mellitus After Treatment From 24-28 Weeks' Gestation: A TOBOGM Secondary\n                    Analysis","author":"D Simmons","year":"2024","journal-title":"Diabetes Care"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"e077727","DOI":"10.1136\/bmjopen-2023-077727.","article-title":"Risk factors for premature rupture of membranes in pregnant women: a systematic\n                    review and meta-analysis","volume":"14","author":"D Lin","year":"2024","journal-title":"BMJ-Open"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.2147\/DMSO.S450939.","article-title":"Gestational Diabetes Mellitus Subtypes Classified by Oral Glucose Tolerance Test\n                    and Maternal and Perinatal Outcomes: Results of a Mexican Multicenter\n                    Prospective Cohort Study \"Cuido Mi Embarazo\"","volume":"17","author":"J Ortega-Montiel","year":"2024","journal-title":"Diabetes Metab Syndr Obes"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"S215","DOI":"10.1055\/a-1581-6175","article-title":"Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge \u2013\n                    Kurzfassung der S3-Leitlinie","volume":"16","author":"U Sch\u00e4fer-Graf","year":"2021","journal-title":"Diabetologie"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1038\/s41366-019-0326-z","article-title":"Maternal metabolic factors during pregnancy predict early childhood growth\n                    trajectories and obesity risk: the CANDLE Study","volume":"43","author":"Z Hu","year":"2019","journal-title":"Int J Obes"}],"container-title":["Zeitschrift f\u00fcr Geburtshilfe und Neonatologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2467-8698.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T23:34:02Z","timestamp":1743723242000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2467-8698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,3]]},"references-count":26,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2025,4,3]]},"published-print":{"date-parts":[[2025,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2467-8698","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0948-2393","1439-1651"],"issn-type":[{"value":"0948-2393","type":"print"},{"value":"1439-1651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,3]]}}}