{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:37:50Z","timestamp":1790206670365,"version":"4.1.0"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropediatrics"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Aim\u2003This study aims to investigate the prevalence, intensity, and location of pain in children and adolescents with cerebral palsy (CP) and analyze pain-related symptoms and participation restrictions.<\/jats:p><jats:p>\n          Methods\u2003Children and adolescents aged 2 to 16 years diagnosed with CP were invited to participate in a pain survey. The questionnaire was based on the German Pain Questionnaire for Children, Adolescents and Parents (DSF-KJ). It was administered to children (2\u201311 years) by their caregivers, while adolescents (12\u201316 years) were asked to complete the questionnaire themselves or with the help of their caregivers.<\/jats:p><jats:p>\n          Results\u2003Fifty-seven of 133 children and adolescents with CP (43%) reported having pain in the past 12 months, of whom 17 (30%) reported chronic pain. Patients with Gross Motor Function Classification System (GMFCS) IV\u2013V reported more frequent pain (p\u2009=\u20090.003) and higher pain intensity (p\u2009=\u20090.011). Lower extremity pain was the most common. Twenty-three percent of participants with pain did not receive any treatment. Pain often restricted participation, specifically by reducing sports activity in patients with GMFCS I\u2013III, focusing attention on patients with GMFCS IV\u2013V, and activities with the family in both GMFCS level categories.<\/jats:p><jats:p>\n          Interpretation\u2003Pain is common in children and adolescents with CP and frequently restricts their participation. Therefore, it must be consistently recorded and addressed during the consultation. The goal of treatment should be not only to reduce pain but above all to increase participation.<\/jats:p>","DOI":"10.1055\/a-2474-6503","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:07:43Z","timestamp":1733789263000},"page":"043-050","source":"Crossref","is-referenced-by-count":3,"title":["Pain in Children and Adolescents with Cerebral Palsy: A Cross-sectional Survey Study"],"prefix":"10.1055","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3112-4619","authenticated-orcid":false,"given":"Lena A.","family":"Bischoff","sequence":"additional","affiliation":[{"name":"Pediatric Neurorehabilitation, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Tscherter","sequence":"additional","affiliation":[{"name":"Institute of Social and Preventative Medicine, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Hunziker","sequence":"additional","affiliation":[{"name":"Institute of Social and Preventative Medicine, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Grunt","sequence":"additional","affiliation":[{"name":"Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole T.","family":"Graf","sequence":"additional","affiliation":[{"name":"Clinical Trial Unit, St. Gallen Cantonal Hospital, St. Gallen, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph T.","family":"K\u00fcnzle","sequence":"additional","affiliation":[{"name":"Pediatric Neurorehabilitation, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Broser","sequence":"additional","affiliation":[{"name":"Pediatric Neurorehabilitation, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,12,9]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/dmcn.12865","article-title":"Decreasing prevalence in cerebral palsy: a multi-site European population-based study, 1980 to 2003","volume":"58","author":"E Sellier","year":"2016","journal-title":"Dev Med Child Neurol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1469-8749.2007.tb12629.x","article-title":"Definition and classification of cerebral palsy. 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A multimodal questionnaire for diagnosis and treatment of children and adolescents suffering from chronic pain [in German]","volume":"24","author":"S Schroeder","year":"2010","journal-title":"Schmerz"},{"issue":"01","key":"ref20","first-page":"20","article-title":"Pain-related disability in adolescents suffering from chronic pain. 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