{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T19:52:31Z","timestamp":1784663551964,"version":"3.55.0"},"reference-count":47,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Giant intracranial aneurysms require complex treatment strategies including clipping, coiling, stenting, parent artery occlusion, bypass, or combined procedures. Neurovascular hybrid operating rooms (h-OR) combine a conventional operating theatre with high-resolution digital subtraction angiography (DSA). We describe a one-step combined surgical and endovascular treatment in a h-OR for a pediatric internal carotid artery (ICA) giant aneurysm that can be an optimal solution to manage such challenging cases.<\/jats:p>\n                  <jats:p>An 11-year-old boy presented with rapid onset right hemiparesis and left eyelid ptosis. A 3-month history of headache associated with sporadic vomit was reported. A giant, unruptured, left ICA aneurysm was detected on imaging. The patient underwent surgical trapping of the aneurysm. Intraoperative DSA showed residual backflow from the posterior communicating artery and coils were placed to completely exclude the aneurysm. At 18-month follow-up, the patient showed a complete recovery and magnetic resonance imaging showed a progressive reduction of the sac aneurysm.<\/jats:p>\n                  <jats:p>Due to their morphological variability, intracranial giant aneurysms may require a different procedural strategy instead of direct clipping or coiling. The introduction of h-OR allows combined treatments to be performed simultaneously in the same room setting. The present case shows that combined treatment in a neurovascular h-OR can be an optimal solution to manage challenging cases, such as giant aneurysms, reducing operative time with the added benefit of selecting an appropriate strategy adjustment in a multidisciplinary effort.<\/jats:p>","DOI":"10.1055\/a-2479-5297","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T23:05:24Z","timestamp":1732575924000},"page":"154-160","source":"Crossref","is-referenced-by-count":1,"title":["Combined One-Step Hybrid Treatment for a Pediatric Giant Internal Carotid Artery Aneurysm: A Case Report"],"prefix":"10.1055","volume":"87","author":[{"given":"Giacomo","family":"Pavesi","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Metabolic and Neural Sciences, School of Neurosurgery, University of Modena and Reggio Emilia, Modena, Italy"},{"name":"Neurosurgery Unit, University Hospital of Modena, Modena, Italy"},{"name":"Neuromotor and Rehabilitation Department, Neurosurgery Unit, AUSL RE IRCCS, Reggio Emilia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0855-3297","authenticated-orcid":false,"given":"Julian S.","family":"Rechberger","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Millesi","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selene M.","family":"Cavallo","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Metabolic and Neural Sciences, School of Neurosurgery, University of Modena and Reggio Emilia, Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Serpico","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Metabolic and Neural Sciences, School of Neurosurgery, University of Modena and Reggio Emilia, Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelaide","family":"Valluzzi","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, University Hospital of Modena, Modena, Italy"},{"name":"Neuromotor and Rehabilitation Department, Neurosurgery Unit, AUSL RE IRCCS, Reggio Emilia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Vallone","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, Metabolic Sciences and Neurosciences, Neuroradiology Unit, University of Modena and Reggio Emilia, Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Iaccarino","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Metabolic and Neural Sciences, School of Neurosurgery, University of Modena and Reggio Emilia, Modena, Italy"},{"name":"Neurosurgery Unit, University Hospital of Modena, Modena, Italy"},{"name":"Neuromotor and Rehabilitation Department, Neurosurgery Unit, AUSL RE IRCCS, Reggio Emilia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Dimitriadis","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, University Hospital of Modena, Modena, Italy"},{"name":"Neuromotor and Rehabilitation Department, Neurosurgery Unit, AUSL RE IRCCS, Reggio Emilia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/978-3-7091-1192-5_24","article-title":"The concept of a hybrid operating room: applications in cerebrovascular surgery","volume":"115","author":"J Fandino","year":"2013","journal-title":"Acta Neurochir Suppl (Wien)"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3171\/jns.1990.73.1.0018","article-title":"The international cooperative study on the timing of aneurysm surgery. 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