{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:26:05Z","timestamp":1772079965993,"version":"3.50.1"},"reference-count":43,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Bei Vorliegen eines Glaukoms sind eine fr\u00fchzeitige Diagnose und eine genaue \u00dcberwachung unerl\u00e4sslich, um die Krankheit wirksam zu behandeln und einen weiteren irreversiblen Verlust retinaler Ganglienzellen zu vermeiden. Da es sich beim Glaukom um eine komplexe Erkrankung handelt, die i.\u200ad.\u200aR. zun\u00e4chst asymptomatisch verl\u00e4uft, sind regelm\u00e4\u00dfige klinische und bildgebende Untersuchungen von gro\u00dfer Bedeutung. Als einfach durchzuf\u00fchrende und reproduzierbare Diagnostik hat sich in den letzten Jahren die Darstellung der retinalen Nervenfaserschicht (RNFL) mithilfe der SD-OCT (Spectral-Domain Optical Coherence Tomography) etabliert. Diese Bildgebungstechnik erm\u00f6glicht eine pr\u00e4zise Analyse der RNFL und erm\u00f6glicht eine \u00dcberwachung der retinalen Nervenfaserdicke. In diesem Artikel sollen daher die anatomischen Grundlagen, die zu erwartenden Ver\u00e4nderungen der RNFL beim Vorliegen eines Glaukoms im Vergleich zu einer unauff\u00e4lligen Kontrollaufnahme und die M\u00f6glichkeiten zur\n          Progressionsanalyse diskutiert werden. Dar\u00fcber hinaus werden die Limitationen der Methode aufgezeigt und zur Verf\u00fcgung stehende erg\u00e4nzende OCT-Aufnahmen angesprochen. Die Kenntnis von m\u00f6glichen Fehlerquellen erleichtert eine korrekte Analyse der RNFL-Scans. Tipps f\u00fcr die Interpretation von RNFL-Scans sollen helfen, die zur Verf\u00fcgung stehenden Daten effektiv zu nutzen und fundierte Entscheidungen \u00fcber die Behandlung und das Management von Glaukompatienten zu treffen.<\/jats:p>","DOI":"10.1055\/a-2501-8538","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T22:30:17Z","timestamp":1753396217000},"page":"726-734","source":"Crossref","is-referenced-by-count":2,"title":["Retinal Nerve Fibre Layer OCT for Glaucoma Diagnosis \u2013 Gold Standard or Just a Piece of the Puzzle?"],"prefix":"10.1055","volume":"242","author":[{"given":"Leonie","family":"Bourauel","sequence":"additional","affiliation":[{"name":"Augenklinik, Universit\u00e4t Bonn, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Mercieca","sequence":"additional","affiliation":[{"name":"Augenklinik, Universit\u00e4t Bonn, 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