{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T23:56:46Z","timestamp":1774396606626,"version":"3.50.1"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We retrospectively analyzed patients who underwent prone positioning (PP) for acute respiratory failure after pulmonary endarterectomy (PEA).<\/jats:p>\n                  <jats:p>A total of 125 patients underwent PEA and the outcome related to patients who underwent PP for acute respiratory failure after surgery was analyzed.<\/jats:p>\n                  <jats:p>In all 13 patients (10%) underwent PP at the mean duration of 28.2\u2009\u00b1\u200910.6\u2009hours after surgery and the mean prone time was 29.4\u2009\u00b1\u20099.8\u2009hours. Compared with the pre-prone values, there was a significant improvement in the mean arterial oxygen to fraction of inspired oxygen ratio at the end of PP (119.4\u2009\u00b1\u200912.4 versus 202\u2009\u00b1\u200958.3) (p\u2009=\u20090.0002). Eight patients (61%) revealed a significant improvement in oxygenation with PP. Five patients who remained unresponsive underwent extracorporeal membrane oxygenation and four of them were weaned off successfully. In multivariate logistic stepwise analysis, the need for a moderate inotropy (odds ratio [OR]: 3.1) and low preoperative cardiac index (OR: 0.2) were independent predictors of PP. Under PP, the most common complication was ventilator-associated pneumonia (n\u2009=\u20099, 70%) and PP was found to be an independent predictor of ventilator-associated pneumonia (OR: 10.3). Early mortality was seen in three patients (23%, sepsis in two and adult respiratory distress syndrome in one).<\/jats:p>\n                  <jats:p>In the early care of acute respiratory failure following PTE, PP may be a feasible option, despite an increased risk of ventilator-associated pneumonia. More research involving a larger sample size is necessary.<\/jats:p>","DOI":"10.1055\/a-2508-0644","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T19:03:58Z","timestamp":1735067038000},"page":"191-198","source":"Crossref","is-referenced-by-count":0,"title":["Prone Positioning for Acute Respiratory Failure after PEA: An Initial Experience"],"prefix":"10.1055","volume":"74","author":[{"given":"Koray","family":"Ak","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Marmara University School of Medicine, Marmara Uninersitesi Hastanesi Mimar Sinan Cad. Fevzi cakmak mah. Ust kaynarca kalp ve damar Cerrahisi Bolumu Pendik, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majd","family":"Tarazi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Marmara University School of Medicine, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatih","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Marmara University School of Medicine, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eehnaz Olgun","family":"Y\u0131ld\u0131zeli","sequence":"additional","affiliation":[{"name":"Department of Pulmonology and Intensive Care, Marmara University School of Medicine, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alper","family":"Kararmaz","sequence":"additional","affiliation":[{"name":"Marmara University School of Medicine, Istanbul, Turkey"},{"name":"Department of Anesthesiology and Reanimation, Marmara University School of Medicine, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bulent","family":"Mutlu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Marmara University School of Medicine, Marmara \u00dcniversity Istanbul, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1316-4552","authenticated-orcid":false,"given":"Bedrettin","family":"Yildizeli","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Marmara University School of Medicine, Fevzi Cakmak M. Mimar Sinan C. No: 41, Ust Kaynarca\/Pendik, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/j.athoracsur.2020.06.122","article-title":"Long-term outcomes after pulmonary endarterectomy in 499 patients over a 20-year period","volume":"111","author":"S Miyahara","year":"2021","journal-title":"Ann Thorac Surg"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1183\/09031936.00058112","article-title":"Surgical treatment of chronic thromboembolic pulmonary hypertension","volume":"41","author":"D P Jenkins","year":"2013","journal-title":"Eur Respir J"},{"issue":"10","key":"ref3","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1513\/AnnalsATS.201503-142OC","article-title":"Efficacy of a low-tidal volume ventilation strategy to prevent reperfusion lung injury after pulmonary thromboendarterectomy","volume":"12","author":"D M Bates","year":"2015","journal-title":"Ann Am Thorac Soc"},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1016\/j.athoracsur.2006.07.020","article-title":"Venovenous extracorporeal life support after pulmonary endarterectomy: indications, techniques, and outcomes","volume":"82","author":"P A Thistlethwaite","year":"2006","journal-title":"Ann Thorac Surg"},{"issue":"02","key":"ref5","first-page":"339","article-title":"Cost of extracorporeal membrane oxygenation: evidence from the Rikshospitalet University Hospital, Oslo, Norway","volume":"37","author":"V Mishra","year":"2010","journal-title":"Eur J Cardiothorac Surg"},{"issue":"05","key":"ref6","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1152\/japplphysiol.00223.2002","article-title":"Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans","volume":"93","author":"G Musch","year":"2002","journal-title":"J Appl Physiol"},{"issue":"01","key":"ref7","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13054-021-03552-2","article-title":"Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients","volume":"25","author":"T Langer","year":"2021","journal-title":"Crit Care"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1053\/j.jvca.2021.07.045","article-title":"Prone positioning in postoperative cardiac surgery patients: a narrative review","volume":"36","author":"G Santarpino","year":"2022","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"S 03","key":"ref9","doi-asserted-by":"crossref","first-page":"S240","DOI":"10.1513\/AnnalsATS.201601-014AS","article-title":"Pulmonary endarterectomy. 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patients","volume":"37","author":"A Dhamija","year":"2022","journal-title":"Perfusion"},{"issue":"23","key":"ref16","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1056\/NEJMoa1214103","article-title":"Prone positioning in severe acute respiratory distress syndrome","volume":"368","author":"C Gu\u00e9rin","year":"2013","journal-title":"N Engl J Med"},{"issue":"02","key":"ref17","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1053\/j.semtcvs.2016.04.008","article-title":"Prone positioning in cardiac surgery: for many, but not for everyone","volume":"28","author":"C von Wardenburg","year":"2016","journal-title":"Semin Thorac Cardiovasc Surg"},{"issue":"06","key":"ref18","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1053\/j.jvca.2019.10.055","article-title":"Turning things around: the role of prone positioning in the management of acute respiratory failure after cardiac surgery","volume":"34","author":"S Saha","year":"2020","journal-title":"J Cardiothorac 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A multicenter cohort study and propensity-matched analysis","volume":"18","author":"M Giani","year":"2021","journal-title":"Ann Am Thorac Soc"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2508-0644.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T23:33:29Z","timestamp":1774395209000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2508-0644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,24]]},"references-count":29,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2026,3,24]]},"published-print":{"date-parts":[[2026,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2508-0644","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"value":"0171-6425","type":"print"},{"value":"1439-1902","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,12,24]]},"published":{"date-parts":[[2024,12,24]]}}}