{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T23:56:48Z","timestamp":1774396608040,"version":"3.50.1"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006520","name":"Edwards Lifesciences","doi-asserted-by":"crossref","award":["HVT-R17-011"],"award-info":[{"award-number":["HVT-R17-011"]}],"id":[{"id":"10.13039\/100006520","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The long-term outcomes of combined rapid-deployment aortic valve replacement (RDAVR) with coronary artery bypass graft surgery (CABG) are not well explored. We report 3-year results from the INCA registry on combined RDAVR with CABG.<\/jats:p>\n                  <jats:p>INCA is a prospective, multicenter registry that enrolled 224 patients undergoing RDAVR with CABG at 10 cardiac institutions in Germany. Prosthetic valve hemodynamics, clinical outcomes, and quality of life (QoL) up to 3 years were assessed.<\/jats:p>\n                  <jats:p>The mean age of patients was 73.6\u2009\u00b1\u20096.1 years, and the mean logistic EuroSCORE was 7.8\u2009\u00b1\u20096.0%. The mean number of distal arterial and venous anastomoses was 3.13\u2009\u00b1\u20091.56, aortic cross-clamp time was 79.4\u2009\u00b1\u200924.1\u2009minutes, cardiopulmonary bypass time was 109.6\u2009\u00b1\u200934.5\u2009minutes, and operation time was 224.2\u2009\u00b1\u200962.7\u2009minutes. The majority of implanted valve size was 25\u2009mm. At baseline, 11 patients (4.9.%) had a permanent pacemaker. Postoperatively, 17 patients (7.6%) required a new pacemaker implantation (5.4% valve-related). All-cause mortality at 30 days was 2.2%, and 11.2% at 3 years. Patient QoL (SF-12v2) was significantly restored and maintained for up to 3 years (p\u2009&lt;\u20090.001). Five patients (0.9%) underwent reoperation related to endocarditis. The postimplant mean gradient was 9.2\u2009\u00b1\u20093.7 at discharge and 8.9\u2009\u00b1\u20094.6\u2009mm Hg at 3 years.<\/jats:p>\n                  <jats:p>Combined RDAVR with CABG procedure is safe and effective over time. It offers stable and low transvalvular gradients with satisfactory clinical outcomes at 3 years. The pacemaker rate appears to be slightly increased, with no significant clinical effect at 3 years.<\/jats:p>","DOI":"10.1055\/a-2508-0732","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T18:51:59Z","timestamp":1738003919000},"page":"199-209","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of RDAVR with Coronary Revascularization: 3-year Results from the German INCA Registry"],"prefix":"10.1055","volume":"74","author":[{"given":"Aristidis","family":"Lenos","sequence":"additional","affiliation":[{"name":"Rh\u00f6n Klinikum Campus Bad Neustadt, Bad Neustadt, Bayern, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justus T.","family":"Strauch","sequence":"additional","affiliation":[{"name":"Berufsgenossenschaftliches Universit\u00e4tsklinikum Bergmannsheil, Bochum, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Schl\u00f6micher","sequence":"additional","affiliation":[{"name":"Berufsgenossenschaftliches Universit\u00e4tsklinikum Bergmannsheil, Bochum, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Fleissner","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum D\u00fcsseldorf, Dusseldorf, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana M.","family":"Valencia-Nunez","sequence":"additional","affiliation":[{"name":"Klinikum Links der Weser gGmbH, Bremen, Bremen, German"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Garbade","sequence":"additional","affiliation":[{"name":"Klinikum Links der Weser gGmbH, Bremen, Bremen, German"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Gottardi","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Vascular Surgery, Universit\u00e4ts-Herzzentrum Freiburg Bad Krozingen, Bad Krozingen, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4022-4298","authenticated-orcid":false,"given":"Parwis","family":"Massoudy","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Klinikum Passau, Passau, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Kamler","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsmedizin Essen, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rizwan","family":"Malik","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsmedizin Essen, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Wimmer-Greinecker","sequence":"additional","affiliation":[{"name":"Herz- und Gef\u00e4\u00dfzentrum Bad Bevensen, Bad Bevensen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Walther","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Frankfurt, Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Gummert","sequence":"additional","affiliation":[{"name":"Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4970-2110","authenticated-orcid":false,"given":"Peter","family":"Bramlage","sequence":"additional","affiliation":[{"name":"Institute for Pharmacology and Preventive Medicine, Cloppenburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anno","family":"Diegeler","sequence":"additional","affiliation":[{"name":"Rh\u00f6n Klinikum Campus Bad Neustadt, Bad Neustadt, Bayern, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,1,27]]},"reference":[{"issue":"06","key":"ref1","first-page":"504","article-title":"Aortic valve replacement with sutureless and rapid deployment aortic valve prostheses","volume":"13","author":"P Berretta","year":"2016","journal-title":"J Geriatr Cardiol"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.ijsu.2010.10.007","article-title":"Cross-clamp time is an independent predictor of mortality and morbidity in low- and high-risk cardiac patients","volume":"9","author":"N Al-Sarraf","year":"2011","journal-title":"Int J 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