{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T04:18:19Z","timestamp":1744863499297,"version":"3.40.4"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund Die kongenitale Tr\u00e4nenwegstenose, eine h\u00e4ufige Erkrankung bei Neugeborenen, ist durch eine Verengung des Tr\u00e4nenwegsystems, h\u00e4ufig am Ductus nasolacrimalis, gekennzeichnet. In den meisten F\u00e4llen \u00f6ffnet sich der Tr\u00e4nenweg spontan im 1.\u2009Lebensjahr, unterst\u00fctzt durch Massagen. Bei fehlender Besserung kann eine operative Sondierung erforderlich sein. Ziel dieser Studie war die Analyse der Erscheinungsbilder und Ergebnisse operativ behandelter Tr\u00e4nenwegstenosen bei Kindern in unserer Klinik.<\/jats:p><jats:p>\n          Patienten und Methoden In einer retrospektiven Analyse wurden elektronische Krankenakten von Patienten unter 18 Jahren ausgewertet, die zwischen 2011 und 2023 wegen einer kongenitalen Tr\u00e4nenwegstenose behandelt wurden. Erfasst wurden demografische Daten, Symptome, Lokalisation der Stenose, operative Therapie und Ergebnisse. Zudem wurden Eltern der Patienten zur postoperativen Situation und Symptomatik befragt. Die Studie wurde von der Kantonalen Ethikkommission Z\u00fcrich (BASEC2022-00830) genehmigt.<\/jats:p><jats:p>\n          Resultate Von insgesamt 147 identifizierten Patienten (39 weiblich, 62 m\u00e4nnlich) konnte bei 69% eine Analyse mit vorliegendem Einverst\u00e4ndnis erfolgen. Das Alter bei Erstuntersuchung lag zwischen 8 Monaten und 12 Jahren (median 27 Monate). Eine unilaterale Stenose wurde bei 69% und eine bilaterale bei 31% festgestellt. Die h\u00e4ufigsten Symptome waren Epiphora (95%), verklebte Zilien (68%), muk\u00f6ses Sekret (23%) und R\u00f6tung der Lider\/Konjunktiva (19%). Bei 11% wurde intraoperativ eine Malformation festgestellt. Eine 2. Sondierung war bei 10% notwendig, wobei das Alter zwischen 18 und 69 Monaten lag (Median 38 Monate). Eine Dakryozystorhinostomie wurde bei 4% durchgef\u00fchrt (Alter 92\u200a\u2013\u200a145 Monate, median 113 Monate). Nach der Operation berichteten 70,5% subjektiv und\/oder objektiv \u00fcber Beschwerdefreiheit, 22,7% \u00fcber anhaltende Epiphora und 6,8% \u00fcber verkrustete Zilien. Bei 77\/101 lag eine Beantwortung des Fragebogens vor. Hierbei berichteten 92%, dass das tr\u00e4nende Auge nicht\n          mehr vorhanden war und 96% ben\u00f6tigten keine Therapie mehr. 97% gaben an, dass die Operation ohne Komplikationen verlief, 17% erlebten erneut tr\u00e4nende Augen, und 6% ben\u00f6tigten zus\u00e4tzliche, nicht tr\u00e4nenwegbezogene Behandlungen.<\/jats:p><jats:p>\n          Fazit In den meisten F\u00e4llen ist eine alleinige Sondierung und Sp\u00fclung zur Heilung ausreichend. Eine tempor\u00e4re Sondeneinlage ist h\u00e4ufiger bei \u00e4lteren Kindern notwendig. Eine Intervention nach dem 18. Lebensmonat beeinflusst die Heilung nicht negativ.<\/jats:p>","DOI":"10.1055\/a-2511-6524","type":"journal-article","created":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T23:57:56Z","timestamp":1740700676000},"page":"310-315","source":"Crossref","is-referenced-by-count":0,"title":["Outcome bei kongenitaler Tr\u00e4nenwegstenose"],"prefix":"10.1055","volume":"242","author":[{"given":"Bardh","family":"Mulaj","sequence":"additional","affiliation":[{"name":"Medizinische Fakult\u00e4t, Universit\u00e4t Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Patzelt","sequence":"additional","affiliation":[{"name":"Augenklinik, Universit\u00e4tsSpital Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karla","family":"Chaloupka","sequence":"additional","affiliation":[{"name":"Augenklinik, Universit\u00e4tsSpital Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6298-615X","authenticated-orcid":false,"given":"Christina","family":"Gerth-Kahlert","sequence":"additional","affiliation":[{"name":"Augenklinik, Universit\u00e4tsSpital Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1136\/bjophthalmol-2018-312074","article-title":"Incidence and clinical characteristics of congenital nasolacrimal duct obstruction","volume":"103","author":"S Sathiamoorthi","year":"2019","journal-title":"Br J Ophthalmol"},{"volume-title":"Nasolacrimal Duct Obstruction","year":"2024","author":"Y Perez","key":"ref2"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s10792-016-0208-5","article-title":"The natural process of congenital nasolacrimal duct obstruction and 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