{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T04:14:06Z","timestamp":1749615246254,"version":"3.41.0"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1055\/a-2521-3214","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T22:34:11Z","timestamp":1749594851000},"page":"243-254","source":"Crossref","is-referenced-by-count":0,"title":["Subtypen der Parkinson-Krankheit"],"prefix":"10.1055","volume":"93","author":[{"given":"Georg","family":"Ebersbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1001\/archneur.65.6.705","article-title":"There is no Parkinson disease","volume":"65","author":"W J Weiner","year":"2008","journal-title":"Arch Neurol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1002\/mds.29708","article-title":"Transitioning from subtyping to precision medicine in parkinson\u02bcs disease: a\n                    purpose-driven approach","volume":"39","author":"C Marras","year":"2024","journal-title":"Mov Disord"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.parkreldis.2021.05.016","article-title":"The inconsistency and instability of Parkinson\u02bcs disease motor subtypes","volume":"88","author":"R von Coelln","year":"2021","journal-title":"Parkinsonism Relat Disord"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"395","DOI":"10.3233\/JPD-202472","article-title":"Parkinson\u02bcs disease subtypes: critical appraisal and recommendations","volume":"11","author":"T A Mestre","year":"2021","journal-title":"J Parkinsons Dis"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1002\/mds.27528","article-title":"Electroencephalography-based machine learning for cognitive profiling in\n                    Parkinson\u02bcs disease: preliminary results","volume":"34","author":"N Betrouni","year":"2019","journal-title":"Mov Disord"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1017\/S0033291715002196","article-title":"Anxiety and anxious-depression in Parkinson\u02bcs disease over a 4-year period: a\n                    latent transition analysis","volume":"46","author":"S Landau","year":"2016","journal-title":"Psychol Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1212\/wnl.40.10.1529","article-title":"Variable expression of Parkinson\u02bcs disease: a base-line analysis of the DATATOP\n                    cohort. The Parkinson Study Group","volume":"40","author":"J Jankovic","year":"1990","journal-title":"Neurology"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1212\/WNL.0000000000002768","article-title":"Postural instability and gait are associated with severity and prognosis of\n                    Parkinson disease","volume":"86","author":"J F van der Heeden","year":"2016","journal-title":"Neurology"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.parkreldis.2016.04.027","article-title":"How stable are Parkinson\u02bcs disease subtypes in de novo patients: analysis of the\n                    PPMI cohort?","volume":"28","author":"T Simuni","year":"2016","journal-title":"Parkinsonism Relat Disord"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.1212\/WNL.0000000000002461","article-title":"Age at onset and Parkinson disease phenotype","volume":"86","author":"G Pagano","year":"2016","journal-title":"Neurology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1002\/mdc3.13523","article-title":"Age cutoff for early-onset Parkinson\u02bcs disease: recommendations from the\n                    International Parkinson and Movement Disorder Society Task Force on Early Onset\n                    Parkinson\u02bcs Disease","volume":"9","author":"R Mehanna","year":"2022","journal-title":"Mov Disord Clin Pract"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1002\/mds.26510","article-title":"Nonmotor features of Parkinson\u02bcs disease subtypes","volume":"31","author":"C Marras","year":"2016","journal-title":"Mov Disord"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"105557","DOI":"10.1016\/j.nbd.2021.105557","article-title":"Neuropathological evidence of body-first vs. brain-first Lewy body disease","volume":"161","author":"P Borghammer","year":"2021","journal-title":"Neurobiol Dis"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.3233\/JPD-212761","article-title":"Asymmetric dopaminergic dysfunction in brain-first versus body-first Parkinson\u02bcs\n                    disease subtypes","volume":"11","author":"K Knudsen","year":"2021","journal-title":"J Parkinsons Dis"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1007\/s11910-017-0738-x","article-title":"Subtypes of Parkinson\u02bcs disease: what do they tell us about disease\n                    progression?","volume":"17","author":"S M Fereshtehnejad","year":"2017","journal-title":"Curr Neurol Neurosci Rep"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1001\/jamaneurol.2018.4377","article-title":"Prognosis and neuropathologic correlation of clinical subtypes of Parkinson\n                    disease","volume":"76","author":"E De Pablo-Fernandez","year":"2019","journal-title":"JAMA Neurol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1136\/jnnp-2018-318337","article-title":"Developing and validating Parkinson\u02bcs disease subtypes and their motor and\n                    cognitive progression","volume":"89","author":"M Lawton","year":"2018","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1002\/mds.27132","article-title":"Distinct metabolomic signature in cerebrospinal fluid in early parkinson\u02bcs\n                    disease","volume":"32","author":"J P Trezzi","year":"2017","journal-title":"Mov Disord"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"e348","DOI":"10.1212\/NXG.0000000000000348","article-title":"Genetic risk of Parkinson disease and progression: an analysis of 13\n                    longitudinal cohorts","volume":"5","author":"H Iwaki","year":"2019","journal-title":"Neurol Genet"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1056\/NEJMoa0901281","article-title":"Multicenter analysis of glucocerebrosidase mutations in Parkinson\u02bcs disease","volume":"361","author":"E Sidransky","year":"2009","journal-title":"N Engl J Med"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1002\/mds.26071","article-title":"GBA-associated Parkinson\u02bcs disease: reduced survival and more rapid progression\n                    in a prospective longitudinal study","volume":"30","author":"K Brockmann","year":"2015","journal-title":"Mov Disord"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/S1474-4422(08)70117-0","article-title":"Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated\n                    Parkinson\u02bcs disease: a case-control study","volume":"7","author":"D G Healy","year":"2008","journal-title":"Lancet Neurol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3233\/JPD-225060","article-title":"Pharmacological treatment of tremor in Parkinson\u02bcs disease revisited","volume":"13","author":"W Pirker","year":"2023","journal-title":"J Parkinsons Dis"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"8885386","DOI":"10.1155\/2021\/8885386","article-title":"Delirium after Deep Brain Stimulation in Parkinson\u02bcs Disease","volume":"2021","author":"H Li","year":"2021","journal-title":"Parkinsons Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/mds.27222","article-title":"Quality of life outcome after subthalamic stimulation in Parkinson\u02bcs disease\n                    depends on age","volume":"33","author":"H S Dafsari","year":"2018","journal-title":"Mov Disord"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1007\/s13311-020-00894-7","article-title":"Therapy of Parkinson\u02bcs disease subtypes","volume":"17","author":"C Marras","year":"2020","journal-title":"Neurotherapeutics"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"895430","DOI":"10.3389\/fnagi.2022.895430","article-title":"The role of genetic data in selecting device-aided therapies in patients with\n                    advanced Parkinson\u02bcs disease: a mini-review","volume":"14","author":"G H Chan","year":"2022","journal-title":"Front Aging Neurosci"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1056\/NEJMoa2202867","article-title":"Trial of prasinezumab in early-stage Parkinson\u02bcs disease","volume":"387","author":"G Pagano","year":"2022","journal-title":"N Engl J Med"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1002\/ana.25994","article-title":"Predictors of long-term outcome of subthalamic stimulation in Parkinson\n                    disease","volume":"89","author":"F Cavallieri","year":"2021","journal-title":"Ann Neurol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1159\/000351097","article-title":"Influence of single nucleotide polymorphisms in COMT, MAO-A and BDNF genes on\n                    dyskinesias and levodopa use in Parkinson\u02bcs disease","volume":"13","author":"P Cheshire","year":"2014","journal-title":"Neurodegener Dis"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1002\/acn3.51569","article-title":"Genetic prediction of impulse control disorders in Parkinson\u02bcs disease","volume":"9","author":"D Weintraub","year":"2022","journal-title":"Ann Clin Transl Neurol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1002\/mds.27027","article-title":"Personalized medicine in Parkinson\u02bcs disease: Time to be precise","volume":"32","author":"N Titova","year":"2017","journal-title":"Mov Disord"}],"container-title":["Fortschritte der Neurologie \u00b7 Psychiatrie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2521-3214.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T22:34:26Z","timestamp":1749594866000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2521-3214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":32,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2025,6,10]]},"published-print":{"date-parts":[[2025,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2521-3214","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0720-4299","1439-3522"],"issn-type":[{"value":"0720-4299","type":"print"},{"value":"1439-3522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}