{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T04:13:07Z","timestamp":1748491987856,"version":"3.41.0"},"reference-count":22,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p> Die multiparametrische Magnetresonanztomografie (mpMRT) ist die etablierte\n      Bildgebungsmodalit\u00e4t der Prostata. Multiparametrisch bedeutet in diesem Zusammenhang, dass neben den anatomischen (T1-\n      und T2-gewichtet) noch funktionelle (diffusionsgewichtet) und kontrastmittelverst\u00e4rkte Sequenzen\n      enthalten sind. Die anatomischen Sequenzen erm\u00f6glichen eine hohe Ortsaufl\u00f6sung. Die\n      diffusionsgewichteten Sequenzen (Diffusion-Weighted Imaging, DWI) misst die Bewegung von\n      Wassermolek\u00fclen im Gewebe (Brown\u2019sche Molekularbewegung) und trifft somit Aussagen \u00fcber die\n      Gewebezusammensetzung. Die Kontrastmittelsequenz (Dynamic Contrast-Enhanced, DCE) nutzt\n      hingegen die Gewebeperfusion zur Beurteilung einer m\u00f6glichen Tumorangiogenese. Durch diese\n      Kombination werden mit verschiedenen Sequenzen unterschiedliche Aspekte des Prostatagewebes\n      analysiert. Diese Kombination an Sequenzen hat sich gegen\u00fcber den initialen MRT-Untersuchungen\n      in den 1980er als zun\u00e4chst reine T1-\/T2-Untersuchung der Prostata durchgesetzt. Aufgrund des gro\u00dfen Bedarfs an Prostata-MRT stellt sich zunehmend die Frage, ob aus\n      \u00f6konomischen und versorgungstechnischen Gr\u00fcnden auf eine Sequenz im Rahmen der Untersuchung\n      verzichten werden kann und, falls ja, auf welche. <\/jats:p>","DOI":"10.1055\/a-2523-6010","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T22:53:41Z","timestamp":1746485621000},"page":"258-262","source":"Crossref","is-referenced-by-count":0,"title":["Wie viele MRT-Sequenzen der Prostata werden ben\u00f6tigt?"],"prefix":"10.1055","volume":"56","author":[{"given":"Fabian","family":"Falkenbach","sequence":"additional","affiliation":[{"name":"Martini-Klinik Prostatakarzinomzentrum, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Germany"},{"name":"Division of Urology, Research Center of the University of Montr\u00e9al, Montr\u00e9al, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Inderhees","sequence":"additional","affiliation":[{"name":"Martini-Klinik Prostatakarzinomzentrum, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Bud\u00e4us","sequence":"additional","affiliation":[{"name":"Martini-Klinik Prostatakarzinomzentrum, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Germany"},{"name":"Klinik und Poliklinik f\u00fcr Urologie, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.1056\/NEJMoa1801993","article-title":"MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis","volume":"378","author":"V Kasivisvanathan","year":"2018","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/s1470-2045(18)30569-2","article-title":"Use of prostate systematic and targeted biopsy on the basis of multiparametric MRI in biopsy-naive patients (MRI-FIRST): a prospective, multicentre, paired diagnostic study","volume":"20","author":"O Rouvi\u00e8re","year":"2019","journal-title":"Lancet Oncol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.eururo.2024.03.027","article-title":"EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer-2024 Update. 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