{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T23:40:04Z","timestamp":1748475604043,"version":"3.41.0"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die initiale Diagnose und das Staging des Harnblasenkarzinoms birgt Herausforderungen.\n      TUR-B und CT-Diagnostik sind bei der Aussage einer Muskelinvasion und der Invasion des\n      perivesikalen Fetts limitiert. Die multiparametrische MRT (mpMRT) der Harnblase erlaubt eine\n      zuverl\u00e4ssige Aussage \u00fcber eine Muskelinvasion eines vorliegenden Harnblasentumors.\n      Mittlerweile liegen zahlreiche retro- und prospektive Studien vor, die eine sehr hohe\n      diagnostische Genauigkeit der mpMRT in dieser Fragestellung attestieren. Aktuelle Metaanalysen\n      zeigen Sensitivit\u00e4tswerte von bis zu 90% bei gleichzeitig hoher Spezifit\u00e4t von &gt;85%. Das\n      \u201eVesical Imaging-Reporting and Data System\u201c (VI-RADS) der mpMRT der Harnblase ist ein\n      standardisiertes und klinisch einfach anzuwendendes Befundsystem. Die EAU-Leitlinien sehen die\n      mpMRT und das VI-RADS-System zum lokalen Staging beim Harnblasenkarzinom vor. Auch ein\n      k\u00fcrzlich ver\u00f6ffentlichtes Consensus Statement auf Basis einer Delphi-Conference von 92\n      internationalen Experten empfiehlt den Einsatz der mpMRT in verschiedenen klinischen\n      Situationen, u.a. vor und nach einer TUR-B, wenn eine Muskelinvasion m\u00f6glich ist oder w\u00e4hrend\n      der neoadjuvanten Chemotherapie.Die mpMRT der Harnblase kann basierend auf einer guten Evidenzlage mittlerweile in verschiedenen klinischen Szenarien eine sinnvolle Erg\u00e4nzung zur bereits etablierten Diagnostik beim Harnblasenkarzinom darstellen. Die Kosten und die limitierte Erfahrung stehen einem breiten Einsatz aktuell noch im Weg.<\/jats:p>","DOI":"10.1055\/a-2528-0195","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T22:52:28Z","timestamp":1746658348000},"page":"248-257","source":"Crossref","is-referenced-by-count":0,"title":["mpMRT der Harnblase \u2013 Stellenwert und klinischer Einsatz"],"prefix":"10.1055","volume":"56","author":[{"given":"Kristina","family":"Tuchenhagen","sequence":"additional","affiliation":[{"name":"Urology, Urologische Klinik Planegg, Planegg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tibor","family":"Vag","sequence":"additional","affiliation":[{"name":"Radiology Planegg, Conradia Munich, Planegg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian Christian","family":"Kriegmair","sequence":"additional","affiliation":[{"name":"Urology, Urologische Klinik Planegg, Planegg, Germany"},{"name":"Urology, 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